{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T22:33:32Z","timestamp":1793226812934,"version":"4.5.0"},"reference-count":45,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIH","award":["R01 AI110112"],"award-info":[{"award-number":["R01 AI110112"]}]},{"name":"NIH","award":["303382\/2022-8"],"award-info":[{"award-number":["303382\/2022-8"]}]},{"name":"NIH","award":["RPG-2024-342"],"award-info":[{"award-number":["RPG-2024-342"]}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"crossref","award":["R01 AI110112"],"award-info":[{"award-number":["R01 AI110112"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"crossref","award":["303382\/2022-8"],"award-info":[{"award-number":["303382\/2022-8"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"crossref","award":["RPG-2024-342"],"award-info":[{"award-number":["RPG-2024-342"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000275","name":"Leverhulme Trust","doi-asserted-by":"crossref","award":["R01 AI110112"],"award-info":[{"award-number":["R01 AI110112"]}],"id":[{"id":"10.13039\/501100000275","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000275","name":"Leverhulme Trust","doi-asserted-by":"crossref","award":["303382\/2022-8"],"award-info":[{"award-number":["303382\/2022-8"]}],"id":[{"id":"10.13039\/501100000275","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000275","name":"Leverhulme Trust","doi-asserted-by":"crossref","award":["RPG-2024-342"],"award-info":[{"award-number":["RPG-2024-342"]}],"id":[{"id":"10.13039\/501100000275","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mem. Inst. Oswaldo Cruz"],"abstract":"<jats:p>BACKGROUND Malaria remains a major public health challenge in the Brazilian Amazon, where ecological heterogeneity and socio-economic vulnerability hinder the effectiveness of vector elimination. The primary vector, Nyssorhynchus darlingi, shows substantial spatiotemporal variation influenced by land-use changes and local microclimates.  OBJECTIVES Investigate how land cover and microclimatic factors affect Ny. darlingi human biting rate (HBR) across different Amazonian ecoregions.  METHODS HBR was measured through human landing catches at 70 sites in four ecoregions, with simultaneous temperature and humidity recordings. Landscape composition was quantified within 100-, 250-, and 500-m buffers. Data were analyzed using linear regressions, mixed-effects models, and principal component analysis.  FINDINGS We recorded 14,689 mosquito bites across 384 events. HBR was highest in areas with intermediate forest degradation and was positively associated with temperature and negatively with humidity. Floodable vegetation was the strongest land cover predictor, especially at the 500-m scale. Intrazonal variation exceeded interzonal differences.  MAIN CONCLUSIONS Local environmental conditions, particularly floodable vegetation near human settlements, strongly influence Ny. darlingi activity. Vector elimination in the Amazon should adopt climate-sensitive, spatially targeted strategies informed by land cover and microclimate data.<\/jats:p>","DOI":"10.1590\/0074-02760250171","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T11:17:27Z","timestamp":1773659847000},"source":"Crossref","is-referenced-by-count":1,"title":["Reframing vector control: land use and climate shape malaria risk in Amazonian communities"],"prefix":"10.1590","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4244-9637","authenticated-orcid":false,"given":"Andr\u00e9 Luis","family":"Acosta","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil; University of Oxford,  United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo Sterlino","family":"Bergo","sequence":"additional","affiliation":[{"name":"Instituto Pasteur de S\u00e3o Paulo,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elder Augusto G","family":"Figueira","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o de Vigil\u00e2ncia em Sa\u00fade do Amazonas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan E","family":"Conn","sequence":"additional","affiliation":[{"name":"New York State Department of Health,  USA; State University of New York-Albany,  USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Anice Mureb","family":"Sallum","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2026]]},"reference":[{"key":"ref1","series-title":"World malaria report 2024. 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