{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:42:43Z","timestamp":1777434163199,"version":"3.51.4"},"reference-count":30,"publisher":"FapUNIFESP (SciELO)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mem. Inst. Oswaldo Cruz"],"published-print":{"date-parts":[[2013,12,6]]},"DOI":"10.1590\/0074-0276130425","type":"journal-article","created":{"date-parts":[[2014,1,16]],"date-time":"2014-01-16T17:07:09Z","timestamp":1389892029000},"page":"1009-1013","source":"Crossref","is-referenced-by-count":11,"title":["Morbidity of Chagas heart disease in the microregion of Rio Negro, Amazonian Brazil: a case-control study"],"prefix":"10.1590","volume":"108","author":[{"given":"Jose Rodrigues","family":"Coura","sequence":"first","affiliation":[{"name":"Instituto Oswaldo Cruz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Albajar","family":"Vinas","sequence":"additional","affiliation":[{"name":"World Health Organization, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia Maria","family":"Brum-Soares","sequence":"additional","affiliation":[{"name":"Medicos sem Fronteiras, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea Silvestre de","family":"Sousa","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisa Clinica-Fiocruz, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio Salles","family":"Xavier","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisa Clinica-Fiocruz, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Emerg\u00eancia da infec\u00e7\u00e3o chag\u00e1sica humana em \u00e1reas do Rio Negro, estado do Amazonas","author":"Albajar PV","year":"2003"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1590\/S0037-86822003000300013","article-title":"Miocardiopatia dilatada em pacientes com infec\u00e7\u00e3o chag\u00e1sica cr\u00f4nica. Relato de dois casos fatais aut\u00f3ctones do Rio Negro, estado do Amazonas","volume":"36","author":"Albajar PV","year":"2003","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref3","series-title":"Estudo morfobiol\u00f3gico, histopatol\u00f3gico e isoenzim\u00e1tico de isolados de Trypanosoma cruzi (Chagas 1909) e Trypanosoma rangeli (Tejera 1920)","author":"Araujo IB","year":"2000"},{"key":"ref4","first-page":"170","volume":"43","author":"Brum-Soares LM","year":"2010","journal-title":"Morbidade da doen\u00e7a de Chagas em pacientes aut\u00f3ctones da microrregi\u00e3o do Rio Negro, estado do Amazonas"},{"key":"ref5","first-page":"873","article-title":"Infection naturelle d\u00eas singes du Par\u00e1 (Chrysotrix sciureus) par Trypanosoma cruzi","volume":"90","author":"Chagas C","year":"1924","journal-title":"Comp Rend S\u00e9anc Soc Biol Ses Fin"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1590\/S0074-02762012000200001","article-title":"Risks of endemicity, morbidity and perspectives regarding the control of Chagas disease in the Amazon Region","volume":"107","author":"Coura JR","year":"2012","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1590\/S0074-02761999000700074","article-title":"Chagas disease: from bush to huts and houses. Is it the case of the Brazilian Amazon?","volume":"94","author":"Coura JR","year":"1999","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S1471-4922(01)02200-0","article-title":"Emerging Chagas disease in Amazonian Brazil","volume":"18","author":"Coura JR","year":"2002","journal-title":"Trends Parasitol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1590\/S0036-46651994000400009","article-title":"Chagas disease in the Brazilian Amazon. I - A short review","volume":"36","author":"Coura JR","year":"1994","journal-title":"Rev Inst Med Trop S\u00e3o Paulo"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1590\/0074-0276130303","article-title":"A new survey of the serology of human Trypanosoma cruzi infection in the Rio Negro microregion, Brazilian Amazon: a critical analysis","volume":"108","author":"Coura JR","year":"2013","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"ref11","first-page":"15","article-title":"Doen\u00e7a de Chagas na Amaz\u00f4nia brasileira","volume":"26","author":"Coura JR","year":"1993","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1590\/S0036-46651995000200003","article-title":"Chagas disease in the Brazilian Amazon. II - A serological survey","volume":"37","author":"Coura JR","year":"1995","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1590\/S0036-46651995000500006","article-title":"Chagas disease in the Brazilian Amazon. III - A cross-sectional study","volume":"37","author":"Coura JR","year":"1995","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1590\/S0037-86822002000600021","article-title":"Doen\u00e7a de Chagas na Amaz\u00f4nia: esbo\u00e7o da situa\u00e7\u00e3o atual e perspectiva de preven\u00e7\u00e3o","volume":"35","author":"Dias JCP","year":"2002","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1590\/1809-43921977073438","article-title":"Mol\u00e9stia de Chagas na Amaz\u00f4nia. Ocorr\u00eancia de seis casos suspeitos, aut\u00f3ctones, sorologicamente positivos","volume":"7","author":"Ferraroni JJ","year":"1977","journal-title":"Acta Amaz"},{"key":"ref16","series-title":"Din\u00e2mica das doen\u00e7as infecciosas e parasit\u00e1rias","first-page":"642","volume-title":"Doen\u00e7a de Chagas na Amaz\u00f4nia brasileira","author":"Junqueira ACV","year":"2013","edition":"2nd ed."},{"key":"ref17","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1590\/S0037-86822011000600009","article-title":"Serological survey for Chagas disease in rural areas of Manaus, Coar\u00ed and Tef\u00e9, in the Western Brazilian Amazon","volume":"44","author":"Magalh\u00e3es BML","year":"2011","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref18","first-page":"413","article-title":"Cardiac attacks in patients with acute Chagas disease in a family micro-outbreak, in Abaetetuba, Brazilian Amazon","volume":"34","author":"Pinto AYN","year":"2001","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref19","article-title":"Ocorr\u00eancia de tripanosom\u00edase aguda familiar no munic\u00edpio de Igarap\u00e9-Miri, Par\u00e1: gravidade de apresenta\u00e7\u00e3o cl\u00ednica em idosos","volume":"36","author":"Pinto AYN","year":"2003","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref20","first-page":"454","article-title":"Emerging acute Chagas disease in Amazonian Brazil: case reports with serious cardiac involvement","volume":"8","author":"Pinto AYN","year":"2004","journal-title":"Braz J Infect Dis"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1590\/S0037-86822008000600011","article-title":"Fase aguda da doen\u00e7a de Chagas na Amaz\u00f4nia brasileira. Estudo de 233 casos do Par\u00e1, Amap\u00e1 e Maranh\u00e3o observados entre 1988 e 2005","volume":"41","author":"Pinto AYN","year":"2008","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref22","article-title":"Clinical follow-up of response to treatment with benznidazol in Amazon: a cohort study of acute Chagas disease","volume":"8","author":"Pinto AYN","year":"2013","journal-title":"PLoS ONE"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1590\/S0034-89101969000200005","article-title":"Considera\u00e7\u00f5es sobre a epidemiologia dos primeiros casos aut\u00f3ctones de doen\u00e7a de Chagas registrados em Bel\u00e9m, Par\u00e1, Brasil","volume":"3","author":"Shaw J","year":"1969","journal-title":"Rev Saude Publica"},{"key":"ref24","author":"Souza-Lima MZ","year":"1985"},{"key":"ref25","first-page":"515","article-title":"Outbreak of acute Chagas disease associated with oral transmission in the Rio Negro region, Brazilian Amazon","volume":"46","author":"Souza-Lima RC","year":"2013","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.trstmh.2008.10.047","article-title":"Analysis of an acute Chagas disease outbreak in the Brazilian Amazon: human cases, triatomines, reservoir mammals and parasites","volume":"103","author":"Valente SAS","year":"2009","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref27","first-page":"68","article-title":"Situa\u00e7\u00e3o atual da doen\u00e7a de Chagas na Amaz\u00f4nia","volume":"26","author":"Valente SAS","year":"1993","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref28","article-title":"Registro de doen\u00e7a de Chagas aguda em Sena Madureira, estado do Acre","volume":"27","author":"Valente SAS","year":"1994","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1590\/S0074-02761999000700077","article-title":"Considerations on the epidemiology and transmission of Chagas disease in the Brazilian Amazon","volume":"94","author":"Valente SAS","year":"1999","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1590\/S0037-86822006000200015","article-title":"Cardiopatia chag\u00e1sica cr\u00f4nica no Rio Negro, estado do Amazonas. Relato de tr\u00eas novos casos aut\u00f3ctones comprovados por exames sorol\u00f3gicos, cl\u00ednicos, radiogr\u00e1ficos do t\u00f3rax, eletro e ecocardiogr\u00e1ficos","volume":"39","author":"Xavier SS","year":"2006","journal-title":"Rev Soc Bras Med Trop"}],"container-title":["Mem\u00f3rias do Instituto Oswaldo Cruz"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/mioc\/v108n8\/0074-0276-mioc-108-8-1009.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,6]],"date-time":"2019-08-06T18:16:55Z","timestamp":1565115415000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0074-02762013000801009&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,6]]},"references-count":30,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,12,6]]}},"alternative-id":["S0074-02762013000801009"],"URL":"https:\/\/doi.org\/10.1590\/0074-0276130425","relation":{},"ISSN":["0074-0276"],"issn-type":[{"value":"0074-0276","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,6]]}}}