{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T10:22:22Z","timestamp":1793182942050,"version":"4.5.0"},"reference-count":38,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiol Bras"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:p>Objetivo: Determinar taxas de defini\u00e7\u00e3o diagn\u00f3stica e complica\u00e7\u00f5es da bi\u00f3psia percut\u00e2nea guiada por tomografia computadorizada (TC) de les\u00f5es \u00f3sseas suspeitas de malignidade. Materiais e M\u00e9todos: Estudo retrospectivo que incluiu 186 casos de bi\u00f3psia percut\u00e2nea guiada por TC de les\u00f5es \u00f3sseas no per\u00edodo de janeiro de 2010 a dezembro de 2012. Todas as amostras foram obtidas usando agulhas de 8 a 10 gauge. Foram coletados dados demogr\u00e1ficos, hist\u00f3ria de neoplasia maligna pr\u00e9via, dados relacionados \u00e0 les\u00e3o, ao procedimento e ao resultado histol\u00f3gico. Resultados: A maioria dos pacientes era do sexo feminino (57%) e a idade m\u00e9dia foi 53,0 \u00b1 16,4 anos. Em 139 casos (74,6%) a suspeita diagn\u00f3stica era met\u00e1stase e os tumores prim\u00e1rios mais comuns foram de mama (32,1%) e pr\u00f3stata (11,8%). Os ossos mais envolvidos foram coluna vertebral (36,0%), bacia (32,8%) e ossos longos (18,3%). Houve complica\u00e7\u00f5es em apenas tr\u00eas pacientes (1,6%), incluindo uma fratura, um caso de parestesia com comprometimento funcional e uma quebra da agulha necessitando remo\u00e7\u00e3o cir\u00fargica. Amostras de 183 les\u00f5es (98,4%) foram consideradas adequadas para diagn\u00f3stico. Resultados malignos foram mais frequentes nos pacientes com suspeita de les\u00e3o secund\u00e1ria e hist\u00f3ria de neoplasia maligna conhecida (p &lt; 0,001) e nos procedimentos orientados pela PET\/CT (p = 0,011). Conclus\u00e3o: A bi\u00f3psia percut\u00e2nea guiada por TC \u00e9 segura e eficaz no diagn\u00f3stico de les\u00f5es \u00f3sseas suspeitas.<\/jats:p>","DOI":"10.1590\/0100-3984.2013.0004","type":"journal-article","created":{"date-parts":[[2014,10,25]],"date-time":"2014-10-25T14:01:36Z","timestamp":1414245696000},"page":"269-274","source":"Crossref","is-referenced-by-count":33,"title":["Bi\u00f3psia percut\u00e2nea de les\u00f5es \u00f3sseas guiada por tomografia computadorizada: taxas de defini\u00e7\u00e3o diagn\u00f3stica e complica\u00e7\u00f5es"],"prefix":"10.1590","volume":"47","author":[{"given":"Macello Jose Sampaio","family":"Maciel","sequence":"first","affiliation":[{"name":"A.C.Camargo Cancer Center,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiang Jeng","family":"Tyng","sequence":"additional","affiliation":[{"name":"A.C.Camargo Cancer Center,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula Nicole Vieira Pinto","family":"Barbosa","sequence":"additional","affiliation":[{"name":"A.C.Camargo Cancer Center,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Almir Galv\u00e3o Vieira","family":"Bitencourt","sequence":"additional","affiliation":[{"name":"A.C.Camargo Cancer Center,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Paulo Kawaoka","family":"Matushita Junior","sequence":"additional","affiliation":[{"name":"A.C.Camargo Cancer Center,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles Edouard","family":"Zurstrassen","sequence":"additional","affiliation":[{"name":"A.C.Camargo Cancer Center,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu Tu","family":"Chung","sequence":"additional","affiliation":[{"name":"A.C.Camargo Cancer Center,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubens","family":"Chojniak","sequence":"additional","affiliation":[{"name":"A.C.Camargo Cancer Center,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","first-page":"315","article-title":"Computed tomographyguided transthoracic needle biopsy of pulmonary nodules","volume":"44","author":"Chojniak R","year":"2011","journal-title":"Radiol Bras"},{"key":"ref2","first-page":"259","article-title":"Percutaneous computed tomography-guided core needle biopsy of soft tissue tumors: results and correlation with surgical specimen analysis","volume":"45","author":"Chojniak R","year":"2012","journal-title":"Radiol Bras"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1590\/S0100-39842012000300005","article-title":"Ultrasound-guided fineneedle aspiration of thyroid nodules: assessment of the ideal number of punctures","volume":"45","author":"Ceratti S","year":"2012","journal-title":"Radiol Bras"},{"key":"ref4","first-page":"75","article-title":"Computed tomography-guided core-needle biopsy of lung lesions: an oncology center experience","volume":"44","author":"Guimar\u00e3es MD","year":"2011","journal-title":"Radiol Bras"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1590\/S0100-39842012000100015","article-title":"Arterial embolization in the treatment of hemobilia after hepatic trauma: a case report","volume":"45","author":"Queiroz HMC","year":"2012","journal-title":"Radiol Bras"},{"key":"ref6","first-page":"251","article-title":"Endovascular treatment of thoracic aortic diseases: a single center result analysis","volume":"45","author":"Novero ER","year":"2012","journal-title":"Radiol Bras"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1445-2197.2005.03332.x","article-title":"Accuracy of computed tomography guided core needle biopsy of musculoskeletal tumours","volume":"75","author":"Altuntas AO","year":"2005","journal-title":"ANZ J Surg"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1148\/radiol.2233011050","article-title":"Diagnosis of primary bone tumors with image-guided percutaneous biopsy: experience with 110 tumors","volume":"223","author":"Jelinek JS","year":"2002","journal-title":"Radiology"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.2214\/ajr.172.5.10227522","article-title":"CT-guided percutaneous biopsy of sclerotic bone lesions: diagnostic yield and accuracy","volume":"172","author":"Leffler SG","year":"1999","journal-title":"AJR Am J Roentgenol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1302\/0301-620X.88B9.17680","article-title":"Surgical biopsy with intraoperative frozen section. An accurate and cost-effective method for diagnosis of musculoskeletal sarcomas","volume":"88","author":"Ashford RU","year":"2006","journal-title":"J Bone Joint Surg Br"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"813","DOI":"10.2214\/ajr.158.4.1546598","article-title":"Percutaneous needle biopsy of musculoskeletal lesions. 2. Cost-effectiveness","volume":"158","author":"Fraser-Hill MA","year":"1992","journal-title":"AJR Am J Roentgenol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s00256-002-0474-3","article-title":"Accuracy of CT-guided biopsies in 359 patients with musculoskeletal lesions","volume":"31","author":"Hau A","year":"2002","journal-title":"Skeletal Radiol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1002\/1097-0142(20001215)89:12<2677::AID-CNCR22>3.0.CO;2-L","article-title":"The percutaneous needle biopsy is safe and recommended in the diagnosis of musculoskeletal masses","volume":"89","author":"Welker JA","year":"2000","journal-title":"Cancer"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"W283","DOI":"10.2214\/AJR.07.3138","article-title":"CT-guided biopsy of bone: a radiologist's perspective","volume":"190","author":"Espinosa LA","year":"2008","journal-title":"AJR Am J Roentgenol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"641","DOI":"10.2214\/ajr.130.4.641","article-title":"Percutaneous needle biopsy of bone in the cancer patient","volume":"130","author":"deSantos LA","year":"1978","journal-title":"AJR Am J Roentgenol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1097\/RCT.0b013e318123e841","article-title":"Musculoskeletal biopsies using computed tomography fluoroscopy","volume":"32","author":"Krause ND","year":"2008","journal-title":"J Comput Assist Tomogr"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"457","DOI":"10.2214\/AJR.10.6145","article-title":"Revisiting CT-guided percutaneous core needle biopsy of musculoskeletal lesions: contributors to biopsy success","volume":"197","author":"Omura MC","year":"2011","journal-title":"AJR Am J Roentgenol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"504","DOI":"10.2214\/AJR.08.1823","article-title":"Imaging-guided percutaneous biopsy of pathologic fractures: a retrospective analysis of 129 cases","volume":"193","author":"Datir A","year":"2009","journal-title":"AJR Am J Roentgenol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1007\/s00330-005-0127-8","article-title":"Image-guided percutaneous biopsy of intramedullary lytic bone lesions: utility of aspirated blood clots","volume":"16","author":"Harish S","year":"2006","journal-title":"Eur Radiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s002709900227","article-title":"Radiologically guided bone biopsy: results of 502 biopsies","volume":"21","author":"Ng CS","year":"1998","journal-title":"Cardiovasc Intervent Radiol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/s00256-005-0038-4","article-title":"CT-guided percutaneous core needle biopsy in deep seated musculoskeletal lesions: a prospective study of 128 cases","volume":"35","author":"Puri A","year":"2006","journal-title":"Skeletal Radiol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1148\/radiol.2483071742","article-title":"Bone and soft-tissue lesions: what factors affect diagnostic yield of image-guided coreneedle biopsy?","volume":"248","author":"Wu JS","year":"2008","journal-title":"Radiology"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"137","DOI":"10.2214\/ajr.166.1.8571862","article-title":"Image-guided percutaneous biopsy of musculoskeletal tumors: an algorithm for selection of specific biopsy techniques","volume":"166","author":"Logan PM","year":"1996","journal-title":"AJR Am J Roentgenol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1148\/radiology.212.3.r99se19682","article-title":"Primary musculoskeletal neoplasms: effectiveness of core-needle biopsy","volume":"212","author":"Yao L","year":"1999","journal-title":"Radiology"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1302\/0301-620X.82B5.9992","article-title":"Cytological diagnosis of skeletal lesions. Fine-needle aspiration biopsy in 110 tumours","volume":"82","author":"Wedin R","year":"2000","journal-title":"J Bone Joint Surg Br"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"809","DOI":"10.2214\/ajr.158.4.1546597","article-title":"Percutaneous needle biopsy of musculoskeletal lesions. 1. Effective accuracy and diagnostic utility","volume":"158","author":"Fraser-Hill MA","year":"1992","journal-title":"AJR Am J Roentgenol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jbspin.2004.03.008","article-title":"Contribution of percutaneous biopsy to definite diagnosis in patients with suspected bone tumor","volume":"72","author":"Vieilleard MH","year":"2005","journal-title":"Joint Bone Spine"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1148\/radiology.149.3.6580673","article-title":"Primary bone tumors: percutaneous needle biopsy. Radiologic-pathologic study of 222 biopsies","volume":"149","author":"Ayala AG","year":"1983","journal-title":"Radiology"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"759","DOI":"10.2214\/ajr.171.3.ajronline_171_3_001","article-title":"Accuracy of CT-guided needle biopsy of musculoskeletal neoplasms","volume":"171","author":"Dupuy DE","year":"1998","journal-title":"AJR Am J Roentgenol"},{"key":"ref30","first-page":"28","article-title":"Computed tomographyguided core needle biopsy for bone and soft tissue tumors","volume":"5","author":"Issakov J","year":"2003","journal-title":"Isr Med Assoc J"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/jso.20504","article-title":"Accurate diagnosis of musculoskeletal lesions by core needle biopsy","volume":"94","author":"Mitsuyoshi G","year":"2006","journal-title":"J Surg Oncol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"644","DOI":"10.2106\/00004623-199605000-00002","article-title":"Diagnostic accuracy and charge-savings of outpatient core needle biopsy compared with open biopsy of musculoskeletal tumors","volume":"78","author":"Skrzynski MC","year":"1996","journal-title":"J Bone Joint Surg Am"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s00776-003-0754-3","article-title":"Application and utility of computed tomography-guided needle biopsy with musculoskeletal lesions","volume":"9","author":"Tsukushi S","year":"2004","journal-title":"J Orthop Sci"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1007\/s00402-009-1030-6","article-title":"CT-guided needle biopsy for musculoskeletal lesions","volume":"130","author":"Tsukushi S","year":"2009","journal-title":"Arch Orthop Trauma Surg"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"e65","DOI":"10.1259\/bjr\/26998246","article-title":"FDG-PET\/CT-guided biopsy of bone metastases sets a new course in patient management after extensive imaging and multiple futile biopsies","volume":"84","author":"Werner MK","year":"2011","journal-title":"Br J Radiol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"e95","DOI":"10.1097\/RLU.0b013e3182443b78","article-title":"Percutaneous biopsy based on PET\/CT findings in cancer patients: technique, indications, and results","volume":"37","author":"Bitencourt AG","year":"2012","journal-title":"Clin Nucl Med"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1102\/1470-7330.2003.0029","article-title":"MRI of bone metastases: the choice of the sequence","volume":"4","author":"Vanel D","year":"2004","journal-title":"Cancer Imaging"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ejrad.2010.06.055","article-title":"Percutaneous CT-guided biopsy of the musculoskeletal system: results of 2027 cases","volume":"77","author":"Rimondi E","year":"2011","journal-title":"Eur J Radiol"}],"container-title":["Radiologia Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/rb\/v47n5\/0100-3984-rb-47-05-0269.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,22]],"date-time":"2017-05-22T19:09:30Z","timestamp":1495480170000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0100-39842014000500269&lng=pt&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["S0100-39842014000500269"],"URL":"https:\/\/doi.org\/10.1590\/0100-3984.2013.0004","relation":{},"ISSN":["0100-3984"],"issn-type":[{"value":"0100-3984","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10]]}}}