{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:48:38Z","timestamp":1792190918970,"version":"4.4.0"},"reference-count":49,"publisher":"FapUNIFESP (SciELO)","issue":"2","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiol Bras"],"abstract":"<jats:p>Abstract The objective of this study was to determine the diagnostic accuracy of ultrasound and electromyography for the detection of fasciculation in patients with amyotrophic lateral sclerosis and to compare detection rates between the two methods. By searching the Cochrane Library, MEDLINE, Excerpta Medica, and Latin-American and Caribbean Health Sciences Literature databases, we identified studies evaluating the diagnostic accuracy and fasciculation detection rates of ultrasound and electromyography. The Quality Assessment of Diagnostic Accuracy Studies, version 2, and RTI item bank tools were used for the evaluation of methodological quality. Ultrasound, for 10 s or 30 s, had a higher detection rate than did electromyography in all muscles evaluated. The overall detection rate (in patients) did not differ significantly between ultrasound for 10 s and ultrasound for 30 s. The accuracy of ultrasound for 10 s was 70% in muscles and 85% in patients. The accuracy of ultrasound for 30 s was 82% in patients. Ultrasound provided detection rates superior to those achieved with electromyography, independent of the examination time and muscles evaluated.<\/jats:p>","DOI":"10.1590\/0100-3984.2019.0055","type":"journal-article","created":{"date-parts":[[2020,4,17]],"date-time":"2020-04-17T19:15:14Z","timestamp":1587150914000},"page":"116-121","source":"Crossref","is-referenced-by-count":22,"title":["Ultrasound versus electromyography for the detection of fasciculation in amyotrophic lateral sclerosis: systematic review and meta-analysis"],"prefix":"10.1590","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7874-9332","authenticated-orcid":false,"given":"M\u00e1rcio Lu\u00eds","family":"Duarte","sequence":"first","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6426-5636","authenticated-orcid":false,"given":"Wagner","family":"Iared","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6986-4937","authenticated-orcid":false,"given":"Acary Souza Bulle","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7897-1198","authenticated-orcid":false,"given":"Lucas Ribeiro dos","family":"Santos","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio Lus\u00edada,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0329-4588","authenticated-orcid":false,"given":"Maria Stella","family":"Peccin","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2020,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1109\/TBME.2015.2465168","article-title":"Ultrasound-based detection of fasciculations in healthy and diseased muscles","volume":"63","author":"Harding PJ","year":"2016","journal-title":"IEEE Trans Biomed Eng"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.34024\/rnc.2000.v8.8955","article-title":"Fascicula\u00e7\u00e3o","volume":"8","author":"Buainain R","year":"2000","journal-title":"Rev Neuroci\u00eancias"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1016\/j.clinph.2014.10.153","article-title":"Dynamic muscle ultrasound - another extension of the clinical examination","volume":"126","author":"Simon NG","year":"2015","journal-title":"Clin Neurophysiol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"49","DOI":"10.2152\/jmi.63.49","article-title":"Which muscle shows fasciculations by ultrasound in patients with ALS","volume":"63","author":"Takamatsu N","year":"2016","journal-title":"J Med Invest"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1055\/s-2008-1060136","article-title":"Faszikulationen - \u00dcberblick \u00fcber Pathophysiologic, klinische Bedeutung und Nachweis","volume":"29","author":"Wenzel S","year":"1998","journal-title":"Klin Neurophysiol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/jon199883148","article-title":"Surface EMG and myosonography in the detection of fasciculations: a comparative study","volume":"8","author":"Wenzel S","year":"1998","journal-title":"J Neuroimaging"},{"key":"ref7","first-page":"337","article-title":"Detection of fasciculations and other types of muscular hyperkinesias with ultrasound","volume":"25","author":"Scheel AK","year":"2004","journal-title":"Ultraschall Med"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00415-015-7965-3","article-title":"Atypical familial amyotrophic lateral sclerosis with initial symptoms of pain or tremor in a Chinese family harboring VAPB-P56S mutation","volume":"263","author":"Di L","year":"2016","journal-title":"J Neurol"},{"issue":"5 Suppl","key":"ref9","doi-asserted-by":"crossref","first-page":"S89","DOI":"10.1016\/j.pmrj.2013.03.020","article-title":"Electrodiagnosis in persons with amyotrophic lateral sclerosis","volume":"5","author":"Joyce NC","year":"2013","journal-title":"PMR"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1055\/s-0031-1271307","article-title":"The office evaluation of weakness","volume":"31","author":"Dimberg EL","year":"2011","journal-title":"Semin Neurol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1590\/S0004-282X2009000400040","article-title":"Amyotrophic lateral sclerosis (ALS): three letters that change the people's life. 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