{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T12:58:50Z","timestamp":1740142730351,"version":"3.37.3"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"2","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiol Bras"],"abstract":"<jats:p>Abstract The temporal lobes are vulnerable to several diseases, including infectious, immune-mediated, degenerative, vascular, metabolic, and neoplastic processes. Therefore, lesions in the temporal lobes can pose a diagnostic challenge for the radiologist. The temporal lobes are connected by structures such as the anterior commissure, corpus callosum, and hippocampal commissure. That interconnectedness favors bilateral involvement in various clinical contexts. This pictorial essay is based on a retrospective analysis of case files from a tertiary university hospital and aims to illustrate some of the conditions that simultaneously affect the temporal lobes, as well as to define some neuroimaging elements that may be useful for the differential diagnosis of these diseases. Using computed tomography and magnetic resonance imaging scans, we illustrate the neuroradiological findings in confirmed cases of human herpesvirus 1, central nervous system tuberculosis, autoimmune encephalitis, Alzheimer's disease, frontotemporal dementia, mesial temporal sclerosis, stroke, kernicterus, megalencephalic leukoencephalopathy with subcortical cysts, low-grade glioma, and secondary lymphoma, the objective being to emphasize the importance of these imaging methods for making the differential diagnosis.<\/jats:p>","DOI":"10.1590\/0100-3984.2019.0134","type":"journal-article","created":{"date-parts":[[2021,3,26]],"date-time":"2021-03-26T11:34:57Z","timestamp":1616758497000},"page":"115-122","source":"Crossref","is-referenced-by-count":3,"title":["Clinical and radiological aspects of bilateral temporal abnormalities: pictorial essay"],"prefix":"10.1590","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1191-4396","authenticated-orcid":false,"given":"Heloisa Sisconeto","family":"Bisinotto","sequence":"first","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7391-1193","authenticated-orcid":false,"given":"Vinicius Menezes","family":"Jarry","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2256-4379","authenticated-orcid":false,"given":"Fabiano","family":"Reis","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2021,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s13244-016-0481-x","article-title":"Bilateral temporal lobe disease: looking beyond herpes encephalitis","volume":"7","author":"Eran A","year":"2016","journal-title":"Insights Imaging"},{"key":"ref2","first-page":"839","article-title":"Proton MR spectroscopy findings in herpes simplex encephalitis","volume":"36","author":"Hitosugi M","year":"1996","journal-title":"Rinsho Shinkeigaku"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1007\/BF00598957","article-title":"MRI of herpes simplex encephalitis","volume":"34","author":"Demaerel P","year":"1992","journal-title":"Neuroradiology"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"e524","DOI":"10.5114\/pjr.2018.81408","article-title":"Magnetic resonance imaging spectrum of intracranial tuberculous lesions: one disease, many faces","volume":"83","author":"Khatri GD","year":"2018","journal-title":"Pol J Radiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.ejrad.2008.02.033","article-title":"(1)H MR spectroscopy of inflammation, infection and ischemia of the brain","volume":"67","author":"Mader I","year":"2008","journal-title":"Eur J Radiol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejrex.2003.12.005","article-title":"Serial cranial MR imaging and single voxel proton MR spectroscopy in paraneoplastic limbic encephalitis","volume":"50","author":"Isik N","year":"2004","journal-title":"Eur J Radiol Extra"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.nic.2012.10.004","article-title":"Magnetic resonance spectroscopy in common dementias","volume":"23","author":"Kantarci K","year":"2013","journal-title":"Neuroimaging Clin N Am"},{"key":"ref8","first-page":"1359","article-title":"Multisection proton MR spectroscopy for mesial temporal lobe epilepsy","volume":"23","author":"Capizzano AA","year":"2002","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1590\/S0004-282X2004000300010","article-title":"The pattern of proton magnetic resonance spectroscopy in non-neoplastic encephalic lesions","volume":"62","author":"Faria AV","year":"2004","journal-title":"Arq Neuropsiquiatr"},{"key":"ref10","first-page":"1571","article-title":"1H MR spectroscopic characteristics of kernicterus: a possible metabolic signature","volume":"26","author":"Oakden WK","year":"2005","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1590\/0004-282X20140206","article-title":"Megalencephalic leukoencephalopathy with subcortical cysts (MLC) - 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