{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:03:04Z","timestamp":1791306184164,"version":"4.3.1"},"reference-count":21,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T00:00:00Z","timestamp":1651449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T00:00:00Z","timestamp":1651449600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T00:00:00Z","timestamp":1651449600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiol Bras"],"abstract":"<jats:p>Abstract  Objective: To evaluate the safety and efficacy of using highly compressible calibrated microspheres in uterine artery embolization (UAE) for the treatment of uterine fibroids.  Materials and Methods: This was a prospective multicenter study. Thirty-two women with symptomatic uterine fibroids were selected for UAE between January 2019 and March 2020. The participants completed the Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire, underwent contrast-enhanced pelvic magnetic resonance imaging (MRI), and were submitted to anti-M\u00fcllerian hormone measurement, subsequently undergoing UAE with Embosoft microspheres. After six months, the patients again completed the UFS-QOL questionnaire and underwent pelvic MRI.  Results: The most common symptoms were abnormal uterine bleeding (in 81.3% of the cases), pelvic pain (in 81.3%), and compression (in 46.9%). Of the 32 patients evaluated, 12 (37.5%) had anemia due to abnormal uterine bleeding. Thirty patients completed the study. Among those patients, we observed median reductions of 21.4% in uterine volume and 15.9% in dominant fibroid volume. We identified no adverse events that could be attributed to the material itself, although there were events attributed to the UAE procedure in general.  Conclusion: For the treatment of uterine fibroids, UAE using Embosoft microspheres shows satisfactory results, providing reductions in uterine and dominant fibroid volumes, with a low rate of adverse events, and improving patient quality of life, as well as demonstrating safety and efficacy.<\/jats:p>","DOI":"10.1590\/0100-3984.2021.0123","type":"journal-article","created":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T19:57:21Z","timestamp":1651521441000},"source":"Crossref","is-referenced-by-count":2,"title":["Uterine artery embolization with highly compressible calibrated microspheres for the treatment of uterine fibroids"],"prefix":"10.1590","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8482-5955","authenticated-orcid":false,"given":"Denis","family":"Szejnfeld","sequence":"first","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8679-7369","authenticated-orcid":false,"given":"R\u00f4mulo Flor\u00eancio Trist\u00e3o","family":"Santos","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6551-1942","authenticated-orcid":false,"given":"Antonio Massamitsu","family":"Kambara","sequence":"additional","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6524-8176","authenticated-orcid":false,"given":"Marcelo Bueno de Oliveira","family":"Colli","sequence":"additional","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6682-2259","authenticated-orcid":false,"given":"Felipe","family":"Nasser","sequence":"additional","affiliation":[{"name":"Hospital Santa Marcelina,  Brazil; Hospital Israelita Albert Einstein,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8762-9204","authenticated-orcid":false,"given":"Mauricio de Sena","family":"Martins","sequence":"additional","affiliation":[{"name":"Hospital Maternidade Leonor Mendes de Barros,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3596-3419","authenticated-orcid":false,"given":"Suzan Menasce","family":"Goldman","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2022,5,2]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/S0140-6736(95)92282-2","article-title":"Arterial embolisation to treat uterine myomata","volume":"346","author":"Ravina JH","year":"1995","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.jvir.2010.01.042","article-title":"Bilateral versus unilateral femoral access for uterine artery embolization: results of a randomized comparative trial","volume":"21","author":"Costantino M","year":"2010","journal-title":"J Vasc Interv Radiol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1056\/NEJMoa1914735","article-title":"Uterine-artery embolization or myomectomy for uterine fibroids","volume":"383","author":"Manyonda I","year":"2020","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.2214\/AJR.05.1383","article-title":"Frequency and extent of uterine perfusion via ovarian arteries observed during uterine artery embolization for leiomyomas","volume":"188","author":"Abbara S","year":"2007","journal-title":"AJR Am J Roentgenol"},{"issue":"2 Pt 1","key":"ref5","first-page":"387","article-title":"ACOG practice bulletin","volume":"112","year":"2008","journal-title":"Alternatives to hysterectomy in the management of leiomyomas. 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