{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:20:44Z","timestamp":1761744044287},"reference-count":28,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Col. Bras. Cir."],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:p>Objective: To evaluate the characteristics of thyroid carcinoma cases treated at a reference hospital for cancer between 2008 and 2010.Methods: we studied 807 cases and analyzed the following clinicopathologic variables: symptoms, risk factors, diagnostic tests, staging, histological type, treatment performed and complications.Results: Females were more affected, with 660 cases (82%). The average age at diagnosis was 44.5 years. Prior exposure to ionizing radiation was reported by 22 (3%) patients, a family history of thyroid cancer by 89 (11%), and 289 (36%) individuals reported other types of cancer in the family. The fine needle aspiration biopsy was the main parameter for surgical indication and was suggestive of carcinoma in 463 patients (57%). Papillary carcinoma was the most common histological type, with 780 cases (96.6%). There were 728 (90%) total thyroidectomies, 43 (5.3%) reoperations or partial thyroidectomies followed by totalization, 23 (2.8%) extended thyroidectomies and only 13 (1.6%) partial thyroidectomies (lobectomy with isthmectomy). Neck dissection associated with thyroidectomy was done in 158 patients (19.5%). We observed a predominance of tumors classified as T1 in 602 (74.6%) patients. Transient hypocalcemia was the most frequent complication.Conclusion: The results show that the worldwide increase in the incidence of thyroid cancer has changed the profile of patients seen at a referral service. In addition, there were changes in the type of surgical treatment used, with increased use of total thyroidectomy in relation to partial and subtotal ones, and decreased use of elective neck dissections.<\/jats:p>","DOI":"10.1590\/0100-69912014005004","type":"journal-article","created":{"date-parts":[[2014,12,3]],"date-time":"2014-12-03T19:42:42Z","timestamp":1417635762000},"page":"320-324","source":"Crossref","is-referenced-by-count":5,"title":["Evolution in the profile of thyroid cancer cases treated in an oncology reference service: what changed in the last 20 years"],"prefix":"10.1590","volume":"41","author":[{"given":"Renan Bezerra","family":"Lira","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery and Otorhinolaryngology, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genival Barbosa de","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Otorhinolaryngology, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o","family":"Gon\u00e7alves Filho","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Otorhinolaryngology, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Paulo","family":"Kowalski","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Otorhinolaryngology, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"issue":"6","key":"ref1","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/j.surg.2010.10.016","article-title":"Analysis of the rising incidence of thyroid cancer using the Surveillance, Epidemiology and End Results national cancer data registry","volume":"148","author":"Cramer JD","year":"2010","journal-title":"Surgery."},{"key":"ref2","series-title":"Estimativa 2012: Incid\u00eancia do c\u00e2ncer no Brasil 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