{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:13:35Z","timestamp":1762899215505},"reference-count":27,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Col. Bras. Cir."],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:p>Objective: To correlate anatomical and functional changes of the oral cavity, pharynx and larynx to the severity of obstructive sleep apnea syndrome (OSAS). Methods : We conducted a cross-sectional study of 66 patients of both genders, aged between 21 and 59 years old with complaints of snoring and \/ or apnea. All underwent full clinical evaluation, including physical examination, nasolarybgoscopy and polisonography. We classified individuals into groups by the value of the apnea-hypopnea index (AHI), calculated measures of association and analyzed differences by the Kruskal-Wallis and chi-square tests. Results : all patients with obesity type 2 had OSAS. We found a relationship between the uvula projection during nasoendoscopy and OSAS (OR: 4.9; p-value: 0.008; CI: 1.25-22.9). In addition, there was a major strength of association between the circular shape of the pharynx and the presence of moderate or severe OSAS (OR: 9.4, p-value: 0.002), although the CI was wide (1.80-53.13). The septal deviation and lower turbinate hypertrophy were the most frequent nasal alterations, however unrelated to gravity. Nasal obstruction was four times more common in patients without daytime sleepiness. The other craniofacial anatomical changes were not predictors for the occurrence of OSAS. Conclusion : oral, pharyngeal and laryngeal disorders participate in the pathophysiology of OSAS. The completion of the endoscopic examination is of great value to the evaluation of these patients.<\/jats:p>","DOI":"10.1590\/0100-69912015005004","type":"journal-article","created":{"date-parts":[[2015,12,5]],"date-time":"2015-12-05T21:04:12Z","timestamp":1449349452000},"page":"289-294","source":"Crossref","is-referenced-by-count":2,"title":["Correlation between the oropharyngo-laryngoscopic findings and the severity of obstructive sleep apnea"],"prefix":"10.1590","volume":"42","author":[{"given":"Priscila Sequeira","family":"Dias","sequence":"first","affiliation":[{"name":"Universidade Federal do Estado do Rio de Janeiro, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Helena de","family":"Araujo-Melo","sequence":"additional","affiliation":[{"name":"Universidade Federal do Estado do Rio de Janeiro, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise Duprat","family":"Neves","sequence":"additional","affiliation":[{"name":"Universidade Federal do Estado do Rio de Janeiro, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas Neves de Andrade","family":"Lemes","sequence":"additional","affiliation":[{"name":"Universidade do Estado do Rio de Janeiro, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuela Salvador","family":"Mosciaro","sequence":"additional","affiliation":[{"name":"Universidade Federal do Estado do Rio de Janeiro, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandro","family":"Bedoya","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"issue":"6","key":"ref1","doi-asserted-by":"crossref","first-page":"549","DOI":"10.4065\/mcp.2010.0810","article-title":"Updates on definition, consequences, and management of obstructive sleep apnea","volume":"86","author":"Park JG","year":"2011","journal-title":"Mayo Clin Proc."},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0272-5231(05)70429-9","article-title":"Pathophysiology of upper airway obstruction during sleep","volume":"19","author":"Badr MS","year":"1998","journal-title":"Clin Chest Med."},{"issue":"4","key":"ref3","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1007\/s11325-013-0824-5","article-title":"The influence of nasal abnormalities in adherence to continuous positive airway pressure device therapy in obstructive sleep apneia patients","volume":"17","author":"Haddad FL","year":"2013","journal-title":"Sleep Breath."},{"issue":"3","key":"ref4","doi-asserted-by":"crossref","first-page":"263","DOI":"10.5664\/jcsm.27497","article-title":"Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults","volume":"5","author":"Epstein LJ","year":"2009","journal-title":"J Clin Sleep Med."},{"issue":"1","key":"ref5","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1378\/chest.125.1.127","article-title":"A community study of sleep-disordered breathing in middle-aged Chinese women in Hong Kong: prevalence and gender difference","volume":"125","author":"Ip MS","year":"2004","journal-title":"Chest."},{"issue":"2","key":"ref6","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1164\/rccm.200302-265OC","article-title":"Prevalence of sleep-disordered breathing and sleep apnea in middle-aged urban Indian men","volume":"169","author":"Udwadia ZF","year":"2004","journal-title":"Am J Respir Crit Care Med."},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.sleep.2009.10.005","article-title":"Obstructive sleep apnea syndrome in the S\u00e3o Paulo Epidemiologic Sleep Study","volume":"11","author":"Tufik S","year":"2010","journal-title":"Sleep Med."},{"issue":"17","key":"ref8","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1056\/NEJM199304293281704","article-title":"The occurrence of sleep-disordered breathing among middle-aged adults","volume":"328","author":"Young T","year":"1993","journal-title":"N Engl J Med."},{"issue":"10","key":"ref9","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1164\/rccm.200404-519OC","article-title":"Prevalence of sleep-disordered breathing in middle-aged Korean men and women","volume":"170","author":"Kim J","year":"2004","journal-title":"Am J Respir Crit Care Med."},{"issue":"21","key":"ref10","first-page":"2445","article-title":"The gender bias in sleep apnea diagnosis","volume":"156","author":"Young T","year":"1996","journal-title":"Are women missed because they have different symptoms? Arch Intern Med."},{"issue":"1","key":"ref11","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1164\/ajrccm.157.1.9706079","article-title":"Effects of age on sleep apnea in men: I","volume":"157","author":"Bixler EO","year":"1998","journal-title":"Prevalence and severity. Am J Respir Crit Care Med."},{"issue":"2","key":"ref12","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1136\/thx.47.2.101","article-title":"Neck circumference and other clinical features in the diagnosis of the obstructive sleep apnea syndrome","volume":"47","author":"Davies RJ","year":"1992","journal-title":"Thorax."},{"issue":"2","key":"ref13","first-page":"118","article-title":"Preditive value of clinical features in diagnosing obstructive sleep apnea","volume":"16","author":"Hoffstein V","year":"1993","journal-title":"Sleep."},{"issue":"8","key":"ref14","doi-asserted-by":"crossref","first-page":"581","DOI":"10.7326\/0003-4819-127-8_Part_1-199710150-00001","article-title":"A predictive morphometric model for the obstructive sleep apnea syndrome","volume":"127","author":"Kushida CA","year":"1997","journal-title":"Ann intern Med."},{"issue":"10","key":"ref15","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1164\/rccm.200112-110OC","article-title":"A decision rule for diagnosis testing in obstructive sleep apnea","volume":"167","author":"Tsai WH","year":"2003","journal-title":"Am J Respir Crit Care Med."},{"issue":"9","key":"ref16","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1288\/00005537-199209000-00017","article-title":"Nasal airway dilation and obstructed breathing in sleep","volume":"102","author":"Metes A","year":"1992","journal-title":"Laryngoscope."},{"issue":"6","key":"ref17","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.rmed.2003.11.017","article-title":"Risk factors associated with habitual snoring and sleep-disordered breathing in a multi-ethnic Asian population: a population-besed study","volume":"98","author":"Khoo SM","year":"2004","journal-title":"Respir Med."},{"issue":"6","key":"ref18","doi-asserted-by":"crossref","first-page":"e258","DOI":"10.1111\/j.1365-2982.2012.01920.x","article-title":"Gastroesophageal and laryngopharyngeal reflux profiles in patients with obstructive sleep apnea\/hipopnea syndrome as determined by combined multichannel intraluminal impedance-pH monitoring","volume":"24","author":"Xiao YL","year":"2012","journal-title":"Neurogastroenterol Motil."},{"issue":"3","key":"ref19","first-page":"429","article-title":"Quantifying the burden of disease: the technical basis for disability-adjusted life years","volume":"72","author":"Murray CJ","year":"1994","journal-title":"Bull World Health Organ."},{"issue":"4","key":"ref20","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1152\/jappl.1997.82.4.1319","article-title":"Anatomy of pharynx in patients with obstructive sleep apnea and in normal subjects","volume":"82","author":"Isono S","year":"1997","journal-title":"J Appl Physiol."},{"issue":"4","key":"ref21","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1177\/0308275X04047841","article-title":"Race, genomics, identities and politics in contemporary Brazil","volume":"24","author":"Santos RV","year":"2004","journal-title":"Crit Anthropol."},{"issue":"7","key":"ref22","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1136\/thx.2003.015867","article-title":"Sleep. 4: Sleepiness, cognitive function, and quality of life in obstructive sleep apnoea\/hypopnoea syndrome","volume":"59","author":"Engleman HM","year":"2004","journal-title":"Thorax."},{"issue":"1","key":"ref23","first-page":"43","article-title":"Deficits of cognitive executive functions in patients with sleep apnea syndrome","volume":"18","author":"Na\u00ebgel\u00e9 B","year":"1995","journal-title":"Sleep."},{"issue":"11","key":"ref24","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1164\/rccm.200505-702OC","article-title":"Association of sleep-disordered breathing and the occurrence of stroke","volume":"172","author":"Arzt M","year":"2005","journal-title":"Am J Respir Crit Care Med."},{"issue":"6","key":"ref25","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1093\/sleep\/14.6.486","article-title":"Sleep-disordered breathing in community-dwelling elderly","volume":"14","author":"Ancoli-Israel S","year":"1991","journal-title":"Sleep."},{"issue":"6","key":"ref26","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1378\/chest.120.6.1930","article-title":"Prevalence of obstructive sleep apnea in a cohort of 1,207 children of southern Italy","volume":"120","author":"Brunetti L","year":"2001","journal-title":"Chest."},{"issue":"4","key":"ref27","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1055\/s-2004-860894","article-title":"Racial differences in clinical presentation of patients with sleep-disordered breathing","volume":"8","author":"Scharf SM","year":"2004","journal-title":"Sleep Breath."}],"container-title":["Revista do Col\u00e9gio Brasileiro de 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