{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:05:08Z","timestamp":1791979508814,"version":"4.4.0"},"reference-count":20,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Col. Bras. Cir."],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:p>ABSTRACT Objective: to evaluate the profile of morbidity and mortality and its predictors related to extensive pelvic resections, including pelvic exenteration, to optimize the selection of patients and achieve better surgical results. Methods: we performed 24 major resections for anorectal pelvic malignancy from 2008 to 2015 in the Instituto do C\u00e2ncer do Cear\u00e1. The factors analyzed included age, weight loss, resected organs, total versus posterior exenteration, angiolymphatic and perineural invasion, lymph node metastasis and overall and disease-free survival. Results: the median age was 57 years and the mean follow-up was ten months. Overall morbidity was 45.8%, with five (20.8%) serious complications. There were no deaths in the first 30 postoperative days. The median overall survival was 39.5 months, and disease-free survival, 30.7 months. Concomitant resection of the bladder was an isolated prognostic factor for higher risk of complications (87.5% vs. 26.7%, p = 0.009). Angiolymphatic invasion and lymph node metastasis did not reach significance with respect to disease-free survival. Conclusion: treatment of advanced anorectal tumors is challenging, often requiring combined resections, such as cystectomy and sacrectomy, and complex reconstructions. The magnitude of the operation still carries a high morbidity rate, but is a procedure considered safe and feasible, with a low mortality and adequate locoregional tumor control when performed in referral centers.<\/jats:p>","DOI":"10.1590\/0100-69912016002005","type":"journal-article","created":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T22:12:54Z","timestamp":1464819174000},"page":"93-101","source":"Crossref","is-referenced-by-count":2,"title":["Extended pelvic resections for the treatment of locally advanced and recurrent anal canal and colorectal cancer: technical aspects and morbimortality predictors aftet 24 consecutive cases"],"prefix":"10.1590","volume":"43","author":[{"given":"Jos\u00e9 Wilson Benevides de","family":"Mesquita Neto","sequence":"first","affiliation":[{"name":"Hospital Haroldo Jua\u00e7aba, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davy Bruno","family":"Machado","sequence":"additional","affiliation":[{"name":"Hospital Haroldo Jua\u00e7aba, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e1rcio J\u00e2nio","family":"Macedo","sequence":"additional","affiliation":[{"name":"Hospital Haroldo Jua\u00e7aba, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego Fonseca","family":"Cordeiro","sequence":"additional","affiliation":[{"name":"Hospital Haroldo Jua\u00e7aba, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eurivaldo Valente de","family":"Brito","sequence":"additional","affiliation":[{"name":"Hospital Haroldo Jua\u00e7aba, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Leite Vieira","family":"Costa","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"issue":"12","key":"ref1","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1002\/ijc.25516","article-title":"Estimates 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