{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T04:46:30Z","timestamp":1777005990228,"version":"3.51.4"},"reference-count":27,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Col. Bras. Cir."],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:p>RESUMO  Objetivo: estudar a preval\u00eancia do c\u00e2ncer de ves\u00edcula biliar em pacientes submetidos \u00e0 colecistectomia no Hospital de Cl\u00ednicas da Universidade Estadual de Campinas.  M\u00e9todos: estudo de preval\u00eancia retrospectivo a partir da an\u00e1lise de laudos de esp\u00e9cimes histopatol\u00f3gicos de pacientes submetidos \u00e0 colecistectomia, no per\u00edodo de janeiro de 2010 a maio de 2015.  Resultados: foram analisados 893 laudos de pacientes submetidos \u00e0 colecistectomia, dos quais 144 de urg\u00eancia e 749 eletivas (16,2% e 83,8%, respectivamente). Segundo o sexo, 72,8% correspondiam ao feminino e 27,2%, ao masculino. Em 12 pacientes (1,3%) foi evidenciado o diagn\u00f3stico de adenocarcinoma de ves\u00edcula biliar e, em um (0,1%), o diagn\u00f3stico de linfoma n\u00e3o Hodgkin. Dos 13 pacientes com neoplasia, sete (53,8%) apresentaram colecistolit\u00edase associada. Em dois doentes (15,3%) foi constatado p\u00f3lipo de ves\u00edcula biliar. Sete (53,8%) doentes foram operados com a hip\u00f3tese diagn\u00f3stica de neoplasia de ves\u00edcula biliar.  Conclus\u00e3o: a preval\u00eancia do adenocarcinoma de ves\u00edcula biliar no presente estudo foi semelhante \u00e0 dos estudos ocidentais e o principal fator de risco foi a colecistolit\u00edase, seguido pela presen\u00e7a de p\u00f3lipos de ves\u00edcula biliar.<\/jats:p>","DOI":"10.1590\/0100-69912017003005","type":"journal-article","created":{"date-parts":[[2017,7,29]],"date-time":"2017-07-29T23:14:15Z","timestamp":1501370055000},"page":"252-256","source":"Crossref","is-referenced-by-count":10,"title":["Preval\u00eancia do c\u00e2ncer de ves\u00edcula biliar em pacientes submetidos \u00e0 colecistectomia: experi\u00eancia do Hospital de Cl\u00ednicas da Faculdade de Ci\u00eancias M\u00e9dicas da Universidade Estadual de Campinas \u2013 UNICAMP"],"prefix":"10.1590","volume":"44","author":[{"given":"M\u00e1rcio","family":"Apodaca-Rueda","sequence":"first","affiliation":[{"name":"Pontif\u00edcia Universidade Cat\u00f3lica de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Everton","family":"Cazzo","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita Barbosa","family":"De-Carvalho","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elinton Adami","family":"Chaim","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3322\/caac.21166","article-title":"Cancer statistics, 2013","volume":"63","author":"Siegel R","year":"2013","journal-title":"CA Cancer J Clin"},{"key":"ref2","series-title":"AJCC Cancer staging manual","first-page":"211","volume-title":"Gallbladder","author":"Edge S","year":"2010","edition":"7th ed"},{"issue":"7","key":"ref3","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1002\/ijc.28161","article-title":"Biliary tract cancer incidence in the United States - Demographic and temporal variations by anatomic site","volume":"133","author":"Castro FA","year":"2013","journal-title":"Int J Cancer"},{"issue":"7","key":"ref4","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1002\/1097-0142(19800401)45:7<1705::AID-CNCR2820450731>3.0.CO;2-S","article-title":"Gallbladder cancer in Hispanic New Mexicans: I. General population, 1957-1977","volume":"45","author":"Devor EJ","year":"1980","journal-title":"Cancer"},{"issue":"10","key":"ref5","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1002\/1097-0142(19951115)76:10<1747::AID-CNCR2820761011>3.0.CO;2-L","article-title":"Risk factors for gallbladder cancer and international collaborative case-control study","volume":"76","author":"Strom BL","year":"1995","journal-title":"Cancer"},{"issue":"5","key":"ref6","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1002\/1097-0142(19800301)45:5<919::AID-CNCR2820450514>3.0.CO;2-4","article-title":"The precursor lesions of invasive gallbladder carcinoma. Hyperplasia, atypical hyperplasia and carcinoma in situ","volume":"45","author":"Albores-Saavedra J","year":"1980","journal-title":"Cancer"},{"issue":"2","key":"ref7","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.suc.2014.01.009","article-title":"Gallbladder cancer","volume":"94","author":"Wernberg JA","year":"2014","journal-title":"Surg Clin N Am"},{"issue":"7","key":"ref8","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1002\/(SICI)1097-0142(19961001)78:7<1515::AID-CNCR21>3.0.CO;2-1","article-title":"Risk factors for gallbladder cancer. An in-ternational collaborative case control study","volume":"78","author":"Serra I","year":"1996","journal-title":"Cancer"},{"issue":"7","key":"ref9","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1002\/ijc.21683","article-title":"Gallbladder cancer worldwide: geographical distribution and risk factors","volume":"118","author":"Randi G","year":"2006","journal-title":"Int J Cancer"},{"issue":"6","key":"ref10","first-page":"419","article-title":"Curative resection in potentially resectable tumours of the gallbladder","volume":"163","author":"De Aretxabala X","year":"1997","journal-title":"Eur J Surg"},{"issue":"1","key":"ref11","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1002\/1097-0142(197807)42:1<330::AID-CNCR2820420150>3.0.CO;2-F","article-title":"Natural history study of gallbladder cancer: a review of 36 years experience at M.D. Anderson Hospital and Tumor Institute","volume":"42","author":"Perpetuo MD","year":"1978","journal-title":"Cancer"},{"issue":"3","key":"ref12","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1245\/ASO.2004.03.011","article-title":"Jaundice predicts advanced disease and early mortality in patients with gallbladder cancer","volume":"11","author":"Hawkins WG","year":"2004","journal-title":"Ann Surg Oncol"},{"issue":"2","key":"ref13","first-page":"133","article-title":"Carcinoma de ves\u00edcula biliar: incid\u00eancia em 10 anos","volume":"2","author":"Conci FM","year":"1993","journal-title":"Rev Cient AMECS"},{"issue":"2","key":"ref14","first-page":"87","article-title":"Colelit\u00edase e c\u00e2ncer prim\u00e1rio da ves\u00edcula biliar","volume":"40","author":"Carneiro PCA","year":"1994","journal-title":"Rev Bras Cancerol"},{"issue":"1\/2","key":"ref15","first-page":"10","article-title":"Frequency of inci-dental gallbladder carcinoma in Brazil","volume":"12","author":"Jukemura J","year":"1997","journal-title":"Arq Bras Cir Dig"},{"issue":"4","key":"ref16","first-page":"269","article-title":"Achado ocasional de carcinoma de ves\u00edcula biliar","volume":"43","author":"Weston AC","year":"1997","journal-title":"Rev Bras Cancerol"},{"issue":"2","key":"ref17","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1590\/S0100-69912002000200006","article-title":"Colelit\u00edase e c\u00e2ncer de ves\u00edcula biliar","volume":"29","author":"Torres OJM","year":"2002","journal-title":"Rev Col Bras Cir"},{"issue":"2","key":"ref18","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1590\/S0100-69912011000200006","article-title":"C\u00e2ncer de ves\u00edcula biliar: experi\u00eancia de 10 anos em um hospital de refer\u00eancia da Amaz\u00f4nia","volume":"38","author":"Ishak G","year":"2011","journal-title":"Rev Col Bras Cir"},{"issue":"1","key":"ref19","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1093\/annonc\/mdn533","article-title":"Epidemiology of biliary tract cancers: an update","volume":"20","author":"Randi G","year":"2009","journal-title":"Ann Oncol"},{"key":"ref20","first-page":"13","author":"Pais-Costa SR"},{"issue":"4","key":"ref21","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/00000658-200010000-00011","article-title":"Gallbladder cancer: comparison of patients presenting initially for definitive operation with those presenting after prior noncurative intervention","volume":"232","author":"Fong Y","year":"2000","journal-title":"Ann Surg"},{"issue":"8","key":"ref22","first-page":"1049","article-title":"Gallbladder and biliary tract carcinoma: a com-prehensive update. Part 2","volume":"18","author":"Daines WP","year":"2004","journal-title":"Oncology (Williston Park)"},{"issue":"1","key":"ref23","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1053\/ejso.2001.1175","article-title":"Incidental carcinoma of the gallbladder","volume":"28","author":"Varshney S","year":"2002","journal-title":"Eur J Surg Oncol"},{"issue":"12","key":"ref24","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1007\/s00268-009-0218-9","article-title":"Incidental gallbladder carcinoma diagno-sed during or after laparoscopic cholecystectomy","volume":"33","author":"Zhang WJ","year":"2009","journal-title":"World J Surg"},{"issue":"3","key":"ref25","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/jso.20944","article-title":"Unsuspected gallbladder cancer diagnosed during or after laparoscopic cholecystectomy","volume":"97","author":"Kwon AH","year":"2008","journal-title":"J Surg Oncol"},{"issue":"3","key":"ref26","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1590\/S0004-28032015000300017","article-title":"Prevalence of incidental gallbladder cancer in a tertiary-care hospital from Pernambuco, Brazil","volume":"52","author":"Martins-Filho ED","year":"2015","journal-title":"Arq Gastroenterol"},{"issue":"2","key":"ref27","first-page":"103","article-title":"Carcinoma prim\u00e1rio de ves\u00edcula biliar","volume":"31","author":"Ziliotto Jr A","year":"1985","journal-title":"Rev Bras Cancerol"}],"container-title":["Revista do Col\u00e9gio Brasileiro de Cirurgi\u00f5es"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/rcbc\/v44n3\/0100-6991-rcbc-44-03-0252.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,9]],"date-time":"2017-08-09T16:06:52Z","timestamp":1502294812000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0100-69912017000300252&lng=pt&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["S0100-69912017000300252"],"URL":"https:\/\/doi.org\/10.1590\/0100-69912017003005","relation":{},"ISSN":["0100-6991"],"issn-type":[{"value":"0100-6991","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6]]}}}