{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T14:26:15Z","timestamp":1770906375744,"version":"3.50.1"},"reference-count":19,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Col. Bras. Cir."],"abstract":"<jats:p>ABSTRACT  Objectives:  to analyze the survival in juvenile melanoma.  Methods:  retrospective study conducted by hospital record review and cancer records of patients aged 0 to 19 years, with histologically proven melanoma and treated between 1997 and 2017 at the Erasto Gaertner Hospital in Curitiba-PR.  Results:  the sample comprised 24 patients, female (62.5%), mean 14.14 \u00b1 4.72 years old, with head and neck melanoma (37.5%), chest (25%) and extremities. (20.8%). Signs and symptoms at diagnosis were increased lesion size (25%), bleeding (20.8%) and pruritus (16.6%). There was a Breslow II and IV index and Clark IV level, with a statistical tendency between Breslow IV and death (p = 0.127), and significance between Clark V and death (p = 0.067). Nine (37.5%) patients had metastases, six (25%) with distant metastases died (p = 0.001), five were girls (20.8%). Surgery was the standard treatment and chemotherapy the most used adjuvant (37.5%). The average time between diagnosis and death was 1.3 \u00b1 1.2 years and survival were 3.7 \u00b1 3.2 years.  Conclusion: there was a delay in diagnosis, high morbidity and mortality and average survival less than five years.<\/jats:p>","DOI":"10.1590\/0100-6991e-20202460","type":"journal-article","created":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T13:54:14Z","timestamp":1606744454000},"source":"Crossref","is-referenced-by-count":3,"title":["Survival analysis of children and adolescents with melanoma"],"prefix":"10.1590","volume":"47","author":[{"given":"K\u00c1TIA SHEYLLA MALTA","family":"PURIM","sequence":"first","affiliation":[{"name":"Universidade Positivo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MURILO VALANDRO","family":"DE-PR\u00c1","sequence":"additional","affiliation":[{"name":"Universidade Positivo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DEBORA CAVASIN","family":"BAHR","sequence":"additional","affiliation":[{"name":"Universidade Positivo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GABRIEL SEIJI","family":"HAYAKAWA","sequence":"additional","affiliation":[{"name":"Universidade Positivo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GIULIA HEREK","family":"ROSSI","sequence":"additional","affiliation":[{"name":"Universidade Positivo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LUCAS DE PAULA","family":"SOARES","sequence":"additional","affiliation":[{"name":"Universidade Positivo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2020]]},"reference":[{"issue":"18","key":"ref1","doi-asserted-by":"crossref","first-page":"4334","DOI":"10.1002\/cncr.25222","article-title":"Prognostic factors for melanoma in children and adolescents a clinicopathologic, single-center study of 137 Patients","volume":"116","author":"Paradela S","year":"2010","journal-title":"Cancer"},{"key":"ref2","year":"2018"},{"issue":"6","key":"ref3","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.jaad.2012.12.953","article-title":"Pediatric melanoma results of a large cohort study and proposal for modified ABCD detection criteria for children","volume":"68","author":"Cordoro KM","year":"2013","journal-title":"J Am Acad Dermatol"},{"issue":"4","key":"ref4","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/ajd.12661","article-title":"Juvenile melanomas Western Australian Melanoma Advisory Service experience","volume":"58","author":"Xu JX","year":"2017","journal-title":"Australas J Dermatol"},{"issue":"22","key":"ref5","doi-asserted-by":"crossref","first-page":"4012","DOI":"10.1002\/cncr.28289","article-title":"Pediatric melanoma Analysis of an international registry","volume":"119","author":"Averbook BJ","year":"2013","journal-title":"Cancer"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"39","DOI":"10.2147\/PHMT.S115534","article-title":"Pediatric melanoma incidence, treatment, and prognosis","volume":"8","author":"Saiyed FK","year":"2017","journal-title":"Pediatric Health Med Ther"},{"issue":"21","key":"ref7","doi-asserted-by":"crossref","first-page":"4735","DOI":"10.1200\/JCO.2005.02.899","article-title":"Pediatric melanoma risk factor and survival analysis of the surveillance, epidemiology and end results database","volume":"23","author":"Strouse JJ","year":"2005","journal-title":"J Clin Oncol"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1002\/(SICI)1097-0142(19990201)85:3<750::AID-CNCR26>3.0.CO;2-5","article-title":"Childhood melanoma survival","volume":"85","author":"Saenz N","year":"1999","journal-title":"Cancer"},{"issue":"5","key":"ref9","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1542\/peds.2012-2520","article-title":"Incidence of childhood and adolescent melanoma in the United States 1973-2009","volume":"131","author":"Wong JR","year":"2013","journal-title":"Pediatrics"},{"issue":"6","key":"ref10","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.26974","article-title":"Pediatric patients with cutaneous melanoma A European study","volume":"65","author":"Brecht IB","year":"2018","journal-title":"Pediatr Blood Cancer"},{"issue":"2","key":"ref11","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.jpeds.2013.10.012","article-title":"Cutaneous melanoma in children and adolescents the Italian rare tumors in pediatric age project experience","volume":"164","author":"Ferrari A","year":"2014","journal-title":"J. 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