{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:47:29Z","timestamp":1787510849127,"version":"build-2736575974"},"reference-count":50,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Col. Bras. Cir."],"abstract":"<jats:p>ABSTRACT Objective: to evaluate esophageal dysmotility (ED) and the extent of Barrett\u2019s esophagus (BE) before and after laparoscopic Nissen fundoplication (LNF) in patients previously diagnosed with BE and ED. Methods: twenty-two patients with BE diagnosed by upper gastrointestinal (GI) endoscopy with biopsies and ED diagnosed by conventional esophageal manometry (CEM) were submitted to a LNF, and followed up with clinical evaluations, upper GI endoscopy with biopsies and CEM, for a minimum of 12 months after the surgical procedure. Results : sixteen patients were male (72.7%) and six were females (27.3%). The mean age was 55.14 (\u00b1 15.52) years old. and the mean postoperative follow-up was 26.2 months. The upper GI endoscopy showed that the mean length of BE was 4.09 cm preoperatively and 3.91cm postoperatively (p=0.042). The evaluation of esophageal dysmotility through conventional manometry showed that: the preoperative median of the lower esophageal sphincter resting pressure (LESRP) was 9.15 mmHg and 13.2 mmHg postoperatively (p=0.006). The preoperative median of the esophageal contraction amplitude was 47.85 mmHg, and 57.50 mmHg postoperatively (p=0.408). Preoperative evaluation of esophageal peristalsis showed that 13.6% of the sample presented diffuse esophageal spasm and 9.1% ineffective esophageal motility. In the postoperative, 4.5% of patients had diffuse esophageal spasm, 13.6% of aperistalsis and 22.7% of ineffective motor activity (p=0.133). Conclusion: LNF decreased the BE extension, increased the LES resting pressure, and increased the amplitude of the distal esophageal contraction; however, it was unable to improve ED.<\/jats:p>","DOI":"10.1590\/0100-6991e-20202637","type":"journal-article","created":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T09:04:34Z","timestamp":1606727074000},"source":"Crossref","is-referenced-by-count":2,"title":["Does the nissen fundoplication procedure improve esophageal dysmotility in patients with barrett\u2019s esophagus?"],"prefix":"10.1590","volume":"47","author":[{"given":"ANGELA M.","family":"FALC\u00c3O","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brazil; Universidade Federal de Pernambuco, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ARY","family":"NASI","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00c9RGIO","family":"SZACHNOWICZ","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FERNANDO","family":"SANTA-CRUZ","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pernambuco, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FRANCISCO C. B. C.","family":"SEGURO","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BRENA F.","family":"SENA","sequence":"additional","affiliation":[{"name":"Escola de Sa\u00fade P\u00fablica T.H. Chan de Harvard, EUA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANDR\u00c9","family":"DUARTE","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RUBENS A.","family":"SALLUM","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"IVAN","family":"CECCONELLO","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2020]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1159\/000486556","article-title":"Rabe SM, Niebisch S Before and after Esophageal Surgery: Which Information Is Needed from the Functional Laboratory. 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