{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T00:10:21Z","timestamp":1783210221148,"version":"3.54.6"},"reference-count":30,"publisher":"FapUNIFESP (SciELO)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cad. Sa\u00fade P\u00fablica"],"abstract":"<jats:p>Abstract: The cascade of care for people living with HIV infection (PLHIV) describes steps in diagnosis, linkage and retention in care, as well as the provision and success of combination antiretroviral therapy (cART). The aim of this study was to evaluate the rates regarding the retention in care, on cART, and suppressed viral load for PLHIV attended at a Brazilian public health network. Data on PLHIV from 116 cities of Paran\u00e1, Southern Brazil, attended from 2012 to 2015, were retrospectively collected through the Laboratory Tests Control System (SISCEL). The number of PLHIV related to care increased about 22.5% from 2012 to 2015 (4,106 to 5,030 individuals). The proportion of PLHIV retained in care showed a trend toward stabilization around 81.7-86.9%. Every year, the use of cART increased up to 90.3% for PLHIV retained in care. Viral load suppression was achieved by 72.8% of patients on cART and 57.1% by those linked to care. Retention in care and HIV viral suppression were more likely to occur in older PLHIV than younger ones; similarly, patients living in medium-sized cities were more susceptible to these factors than in large- or small-sized cities. In conclusion, the study showed a high level of retention in care and HIV suppression on cART, as well as emphasized that current efforts for treating already-infected PLHIV remain a challenge for our health public institutions and may contribute to highlight steps for improvement of the HIV cascade of care in our population.<\/jats:p>","DOI":"10.1590\/0102-311x00009718","type":"journal-article","created":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T11:55:15Z","timestamp":1543578915000},"source":"Crossref","is-referenced-by-count":6,"title":["Cascade of care for people living with HIV infection in Southern Brazil: results from a public health network"],"prefix":"10.1590","volume":"34","author":[{"given":"Ingridt Hildegard","family":"Vogler","sequence":"first","affiliation":[{"name":"Universidade Estadual de Londrina,  Brazil; Universidade Estadual de Londrina,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela Frizon","family":"Alfieri","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Londrina,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heloisa Damazio Bruna","family":"Gianjacomo","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Londrina,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine Regina Delicato de","family":"Almeida","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Londrina,  Brazil; Universidade Estadual de Londrina,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edna Maria Vissoci","family":"Reiche","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Londrina,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2018,11,29]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1056\/NEJMoa1506816","article-title":"Initiation of antiretroviral therapy in early asymptomatic HIV infection","volume":"373","year":"2015","journal-title":"N Engl J Med"},{"key":"ref2","series-title":"Understanding the HIV care continuum"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1089\/apc.2015.0139","article-title":"The HIV care cascade measured over time and by age, sex, and race in a large national integrated care system","volume":"29","author":"Horberg MA","year":"2015","journal-title":"AIDS Patient Care STDS"},{"key":"ref4","doi-asserted-by":"crossref","DOI":"10.7448\/IAS.18.1.19395","article-title":"The HIV care cascade models, measures and moving forward","volume":"18","author":"MacCarthy S","year":"2015","journal-title":"J Int AIDS Soc"},{"key":"ref5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0129376","article-title":"The HIV care continuum changes over time in retention in care and viral suppression","volume":"10","author":"Yehia BR","year":"2015","journal-title":"PLoS One"},{"key":"ref6","series-title":"90-90-90: an ambitious treatment target to help end the AIDS epidemic"},{"key":"ref7","series-title":"Manual t\u00e9cnico de elabora\u00e7\u00e3o da cascata de cuidado cont\u00ednuo do HIV","year":"2017"},{"key":"ref8","first-page":"1389","article-title":"The Family Health Strategy primary health care and the challenge of Brazilian metropolises","volume":"21","author":"Costa NR","year":"2016","journal-title":"Ci\u00eanc Sa\u00fade Coletiva"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"325","DOI":"10.7326\/0003-4819-157-5-201209040-00005","article-title":"US trends in antiretroviral therapy use, HIV RNA plasma viral loads, and CD4 T-lymphocyte cell counts among HIV-infected persons, 2000 to 2008","volume":"157","author":"Althoff KN","year":"2012","journal-title":"Ann Intern Med"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"e24","DOI":"10.2105\/AJPH.2014.302080","article-title":"Retention in care and viral suppression among persons living with HIV\/AIDS in New York City, 2006-2010","volume":"104","author":"Torian LV","year":"2014","journal-title":"Am J Public Health"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"ofu011","DOI":"10.1093\/ofid\/ofu011","article-title":"High mortality among human immunodeficiency virus (HIV)-infected individuals before accessing or linking to HIV care a missing outcome in the cascade of care?","volume":"1","author":"Krentz HB","year":"2014","journal-title":"Open Forum Infect Dis"},{"key":"ref12","first-page":"1618","article-title":"Vital signs HIV prevention through care and treatment - 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