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Sa\u00fade P\u00fablica"],"abstract":"<jats:p>Durante o per\u00edodo de p\u00f3s-comercializa\u00e7\u00e3o, quando medicamentos s\u00e3o usados por grandes popula\u00e7\u00f5es e por per\u00edodos de tempo maiores, eventos adversos (EA) inesperados podem ocorrer, o que pode alterar a rela\u00e7\u00e3o risco-benef\u00edcio dos medicamentos o suficiente para exigir uma a\u00e7\u00e3o regulat\u00f3ria. Eventos adversos s\u00e3o agravos \u00e0 sa\u00fade que podem surgir durante o tratamento com um produto farmac\u00eautico, os quais, no per\u00edodo de p\u00f3s-comercializa\u00e7\u00e3o do medicamento, podem requerer um aumento significativo de cuidados de sa\u00fade e resultar em danos desnecess\u00e1rios aos pacientes, muitas vezes fatais. Portanto, o quanto antes, a descoberta de EA no per\u00edodo de p\u00f3s-comercializa\u00e7\u00e3o \u00e9 um objetivo principal do sistema de sa\u00fade. Alguns pa\u00edses possuem sistemas de vigil\u00e2ncia farmacol\u00f3gica respons\u00e1veis pela coleta de relat\u00f3rios volunt\u00e1rios de EA na p\u00f3s-comercializa\u00e7\u00e3o, mas estudos j\u00e1 demonstraram que, com a utiliza\u00e7\u00e3o de redes sociais, pode-se conseguir um n\u00famero maior e mais r\u00e1pido de relat\u00f3rios. O objetivo principal deste projeto \u00e9 construir um sistema totalmente automatizado que utilize o Twitter como fonte para encontrar EA novos e j\u00e1 conhecidos e fazer a an\u00e1lise estat\u00edstica dos dados obtidos. Para isso, foi constru\u00eddo um sistema que coleta, processa, analisa e avalia tweets em busca de EA, comparando-os com dados da Ag\u00eancia Americana de Controle de Alimentos e Medicamentos (FDA) e do padr\u00e3o de refer\u00eancia constru\u00eddo. Nos resultados obtidos, conseguimos encontrar EA novos e j\u00e1 existentes relacionados ao medicamento doxiciclina, o que demonstra que o Twitter, quando utilizado em conjunto com outras fontes de dados, pode ser \u00fatil para a farmacovigil\u00e2ncia.<\/jats:p>","DOI":"10.1590\/0102-311x00033417","type":"journal-article","created":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T23:18:15Z","timestamp":1558567095000},"source":"Crossref","is-referenced-by-count":4,"title":["O uso do Twitter como minerador de eventos adversos de medicamentos de combate \u00e0 mal\u00e1ria: o caso da doxiciclina"],"prefix":"10.1590","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4476-1277","authenticated-orcid":false,"given":"Felipe Vieira","family":"Duval","sequence":"first","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz,  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