{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T16:43:31Z","timestamp":1775666611153,"version":"3.50.1"},"reference-count":40,"publisher":"FapUNIFESP (SciELO)","issue":"3","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cad. Sa\u00fade P\u00fablica"],"abstract":"<jats:p>El objetivo fue describir las caracter\u00edsticas de la infecci\u00f3n por SARS-CoV-2 entre miembros de hogares, con un caso confirmado primario de COVID-19, en distritos de baja carga de casos en Lima, Per\u00fa, en comparaci\u00f3n con un distrito de alta carga. Estudio retrospectivo de revisi\u00f3n de base de datos secundaria. Se recolect\u00f3 informaci\u00f3n proveniente de una actividad de vigilancia epidemiol\u00f3gica en contactos cercanos (cohabitantes), en 52 hogares de Lima, con un solo miembro con COVID-19. En 10 hogares se realiz\u00f3 una reevaluaci\u00f3n. Se evaluaron variables epidemiol\u00f3gicas y cl\u00ednicas; y su asociaci\u00f3n con el resultado a la prueba serol\u00f3gica r\u00e1pida (presencia de IgG, IgM o ambas). En 40 hogares se encontraron casos secundarios, lo que representa un 49,9% de identificaci\u00f3n en promedio por hogar. Se encontr\u00f3 una tasa de ataque secundaria entre cohabitantes de 53% (125 casos), siendo sintom\u00e1ticos un 77,6% de casos (raz\u00f3n sintom\u00e1ticos\/asintom\u00e1ticos: 3,5). La presencia de fiebre y\/o escalofr\u00edos se encontr\u00f3 en el 40% de las personas con resultado positivo, seguido del dolor de garganta en el 39,2%. La ageusia y anosmia estuvieron presentes en el 22,4% y 20,8% de los casos, respectivamente. Al tener un caso primario de COVID-19 en el hogar, la tasa de ataque secundaria de esta infecci\u00f3n es de 53%; sin embargo, en una proporci\u00f3n importante de hogares evaluados no hubo un caso positivo, m\u00e1s all\u00e1 del caso primario. Las caracter\u00edsticas epidemiol\u00f3gicas y cl\u00ednicas encontradas en este caso estuvieron acorde a lo ya reportado en otras series internacionales.<\/jats:p>","DOI":"10.1590\/0102-311x00238720","type":"journal-article","created":{"date-parts":[[2021,3,12]],"date-time":"2021-03-12T18:54:05Z","timestamp":1615575245000},"source":"Crossref","is-referenced-by-count":13,"title":["Transmisi\u00f3n intra-hogar en personas infectadas por SARS-CoV-2 (COVID-19) en Lima, Per\u00fa"],"prefix":"10.1590","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7280-170X","authenticated-orcid":false,"given":"Yolanda","family":"Angulo-Baz\u00e1n","sequence":"first","affiliation":[{"name":"Instituto Nacional de Salud,  Paraguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7084-088X","authenticated-orcid":false,"given":"Gilmer","family":"Solis-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Salud,  Paraguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4541-275X","authenticated-orcid":false,"given":"Fany","family":"Cardenas","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Salud,  Paraguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0570-4640","authenticated-orcid":false,"given":"Ana","family":"Jorge","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Salud,  Paraguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5745-3383","authenticated-orcid":false,"given":"Joshi","family":"Acosta","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Salud,  Paraguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5120-0713","authenticated-orcid":false,"given":"C\u00e9sar","family":"Cabezas","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Salud,  Paraguay"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2021]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"102433","DOI":"10.1016\/j.jaut.2020.102433","article-title":"The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak","volume":"109","author":"Rothan HA","year":"2020","journal-title":"J Autoimmun"},{"key":"ref2","series-title":"Presidente Vizcarra dio a conocer primer caso de infecci\u00f3n por coronavirus en el Per\u00fa e hizo un llamado a la poblaci\u00f3n a mantener la calma."},{"key":"ref3","series-title":"Minsa lamenta el sensible fallecimiento de dos personas por infecci\u00f3n por COVID-19."},{"key":"ref4","doi-asserted-by":"crossref","first-page":"124","DOI":"10.7861\/clinmed.2019-coron","article-title":"What we know so far COVID-19 current clinical knowledge and research","volume":"20","author":"Lake MA","year":"2020","journal-title":"Clin Med (Lond)"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"taaa021","DOI":"10.1093\/jtm\/taaa021","article-title":"The reproductive number of COVID-19 is higher compared to SARS coronavirus","volume":"27","author":"Liu Y","year":"2020","journal-title":"J Travel Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"2000058","DOI":"10.2807\/1560-7917.ES.2020.25.4.2000058","article-title":"Pattern of early human-to-human transmission of Wuhan 2019 novel coronavirus (2019-nCoV), December 2019 to January 2020","volume":"25","author":"Riou J","year":"2020","journal-title":"Eurosurveillance"},{"key":"ref7","first-page":"11","article-title":"The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - 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