{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:54:58Z","timestamp":1790189698342,"version":"4.1.0"},"reference-count":61,"publisher":"FapUNIFESP (SciELO)","issue":"2","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cad. Sa\u00fade P\u00fablica"],"abstract":"<jats:p>Body fat distribution seems to have different effects in cardiovascular diseases (CVD). We aimed to estimate the associations between lower limbs and trunk fat ratio and the 10-year CVD risk, and isolated risk factors in men and women. A total of 10,917 participants from ELSA-Brasil were eligible for this cross-sectional study. Associations between lower limb\/trunk fat ratio with the percentage of 10-year CVD risk - according to the Framingham Risk Score - and its risk factors (systolic blood pressure, total cholesterol and HDL-cholesterol, diabetes, and use of antihypertensive medication) were performed using generalized linear models, linear and logistic regressions. All analyses were stratified by gender and adjustments were made by age, self-reported skin color, educational attainment, alcohol consumption, leisure physical activity, hypolipidemic drug use and, for women, menopausal status. In this study, 55.91% were women, with a mean age of 52.68 (SD = 6.57) years. A higher lower limb\/trunk fat ratio was related to lower 10-year CVD risk, as well as a reduction in systolic blood pressure, total cholesterol, and antihypertensive drug use, also an increasing HDL-cholesterol in both genders, but this relationship was stronger in women. Besides, a protective relationship to diabetes was observed in women. Higher fat accumulation in the lower body, when compared to the trunk, seems to have a lower risk of CVD and associated risk factors - even in the presence of fat in the abdominal region - with women presenting lower risks than men.<\/jats:p>","DOI":"10.1590\/0102-311x00346520","type":"journal-article","created":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T21:03:02Z","timestamp":1644613382000},"source":"Crossref","is-referenced-by-count":5,"title":["Body fat distribution and its risk for cardiovascular events in 10 years: Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)"],"prefix":"10.1590","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6726-9176","authenticated-orcid":false,"given":"B\u00e1rbara Bruna Rodrigues de","family":"Oliveira","sequence":"first","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7294-3724","authenticated-orcid":false,"given":"Carolina Gomes","family":"Coelho","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7383-7811","authenticated-orcid":false,"given":"Sandhi Maria","family":"Barreto","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5454-2460","authenticated-orcid":false,"given":"Luana","family":"Giatti","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6695-0365","authenticated-orcid":false,"given":"Larissa Fortunato","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2022]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/S0140-6736(18)32203-7","article-title":"Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017.","volume":"392","year":"2018","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"crossref","DOI":"10.1590\/0102-311x00067617","article-title":"Fen\u00f3tipo cintura hipertriglicerid\u00eamica: fatores associados e compara\u00e7\u00e3o com outros indicadores de risco cardiovascular e metab\u00f3lico no ELSA-Brasil.","volume":"34","author":"Freitas RS","year":"2018","journal-title":"Cad Sa\u00fade 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