{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T21:40:34Z","timestamp":1788212434454,"version":"build-2803163510"},"reference-count":34,"publisher":"FapUNIFESP (SciELO)","issue":"8","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cad. Sa\u00fade P\u00fablica"],"abstract":"<jats:p>Este estudo analisou as a\u00e7\u00f5es judiciais de pacientes que solicitaram ao Sistema \u00danico de Sa\u00fade produtos \u00e0 base de canabidiol (CBD) durante o per\u00edodo de 2019 a 2022, descrevendo caracter\u00edsticas sociodemogr\u00e1ficas, cl\u00ednicas e jur\u00eddicas. Trata-se de um estudo transversal composto pela avalia\u00e7\u00e3o das notas t\u00e9cnicas emitidas pelos N\u00facleos de Apoio T\u00e9cnico do Judici\u00e1rio (NatJus), que embasaram as decis\u00f5es judiciais. Os dados foram obtidos do sistema e-NatJus, do Minist\u00e9rio da Justi\u00e7a, utilizando t\u00e9cnicas de web scraping. Regress\u00e3o log\u00edstica foi empregada para estimar raz\u00f5es de chances com intervalos de 95% de confian\u00e7a. Foram analisadas 1.115 notas t\u00e9cnicas das a\u00e7\u00f5es demandantes de CBD, das quais 54,7% dos pacientes eram do sexo masculino, com idade m\u00e9dia de 18,4 anos, em sua maioria da Regi\u00e3o Sul do pa\u00eds (38,8%), e 49,6% buscavam tratamento para epilepsia. Das a\u00e7\u00f5es com pareceres favor\u00e1veis, 28,8% n\u00e3o tinham evid\u00eancias cient\u00edficas, 26,5% pleitearam produtos sem registro na Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria e 25,3% dos que tinham registro n\u00e3o estavam em conformidade com a indica\u00e7\u00e3o terap\u00eautica. Os pacientes da Regi\u00e3o Nordeste tiveram a chance de parecer favor\u00e1vel aumentada em 3 vezes; e os que tinham diagn\u00f3stico de epilepsia, em 2,3 vezes. Os pareceres t\u00e9cnicos que deram suporte aos magistrados para as decis\u00f5es judiciais das demandas de pacientes por produtos \u00e0 base de canabidiol no Brasil estavam, em sua maioria, em conformidade com evid\u00eancias cient\u00edficas, denotando a import\u00e2ncia dos NatJus na qualifica\u00e7\u00e3o do acesso a produtos medicinais no pa\u00eds.<\/jats:p>","DOI":"10.1590\/0102-311xpt024723","type":"journal-article","created":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T11:35:48Z","timestamp":1696851348000},"source":"Crossref","is-referenced-by-count":15,"title":["Judicializa\u00e7\u00e3o de produtos \u00e0 base de canabidiol no Brasil: uma an\u00e1lise de 2019 a 2022"],"prefix":"10.1590","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6267-1278","authenticated-orcid":false,"given":"Ronaldo","family":"Portela","sequence":"first","affiliation":[{"name":"Universidade Federal de Minas Gerais,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4156-0138","authenticated-orcid":false,"given":"Daniel Marques","family":"Mota","sequence":"additional","affiliation":[{"name":"Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5042-4213","authenticated-orcid":false,"given":"Paulo Jos\u00e9 Gon\u00e7alves","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0760-4424","authenticated-orcid":false,"given":"Mariana Dias","family":"Lula","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4836-671X","authenticated-orcid":false,"given":"Bruno Barcala","family":"Reis","sequence":"additional","affiliation":[{"name":"Defensoria P\u00fablica do Estado de Minas Gerais,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1635-5175","authenticated-orcid":false,"given":"Helian Nunes de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0275-8416","authenticated-orcid":false,"given":"Cristina Mariano","family":"Ruas","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2023]]},"reference":[{"key":"ref1","first-page":"103","article-title":"Molecular targets of the phytocannabinoids a complex picture","volume":"103","author":"Morales P","year":"2017","journal-title":"Prog Chem Org Nat Prod"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s00213-020-05712-8","article-title":"Cannabidiol pharmacology and therapeutic targets","volume":"238","author":"Britch SC","year":"2021","journal-title":"Psychopharmacology (Berl)"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"4876","DOI":"10.3390\/ijms22094876","article-title":"The (poly)pharmacology of cannabidiol in neurological and neuropsychiatric disorders molecular mechanisms and targets","volume":"22","author":"Vitale RM","year":"2021","journal-title":"Int J Mol 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