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Sa\u00fade P\u00fablica"],"abstract":"<jats:p>Buscando compreender como as epidemias de zika e chikungunya incitaram o desenvolvimento tecnol\u00f3gico, este estudo realizou levantamento de dados epidemiol\u00f3gicos e prospec\u00e7\u00e3o tecnol\u00f3gica, utilizando dados do Instituto Nacional da Propriedade Industrial (INPI) e do Orbit Intelligence. Ainda, analisou produtos desenvolvidos e em desenvolvimento a n\u00edvel mundial e aqueles registrados no Brasil por meio da Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria (Anvisa). No ano de 2016, observou-se o maior n\u00famero de casos totais para ambas as doen\u00e7as. A prospec\u00e7\u00e3o tecnol\u00f3gica nacional revelou que h\u00e1 interesse global em desenvolver tecnologias para essas doen\u00e7as e depositar suas patentes no Brasil, tendo as empresas como principais depositantes. Por sua vez, a prospec\u00e7\u00e3o tecnol\u00f3gica global mostrou que o ano de 2016 configura-se como importante marco na evolu\u00e7\u00e3o do n\u00famero de patentes para zika e chikungunya, sugerindo que as epidemias brasileiras estimularam o mundo no desenvolvimento de novos insumos para a sa\u00fade. Os Estados Unidos e a China s\u00e3o as principais jurisdi\u00e7\u00f5es, tendo as universidades como maiores depositantes. A an\u00e1lise de produtos a n\u00edvel global revelou que apenas dois chegaram ao mercado para zika e um para chikungunya, e as vacinas est\u00e3o na categoria principal. A busca na Anvisa revelou que h\u00e1 mais produtos registrados para zika do que em compara\u00e7\u00e3o \u00e0 chikungunya. Os principais fabricantes legais s\u00e3o empresas brasileiras, com pedidos de registro realizados principalmente pelas empresas DiaSorin S.p.A., ECO Diagn\u00f3stica Ltda. e Chembio Diagnostics Brazil Ltda. Apesar do vis\u00edvel est\u00edmulo \u00e0 pesquisa, desenvolvimento e patenteamento gerado pelas epidemias de zika e chikungunya no Brasil, isso n\u00e3o garantiu a chegada de novos produtos ao mercado nem acesso da popula\u00e7\u00e3o a eles.<\/jats:p>","DOI":"10.1590\/0102-311xpt090022","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T09:44:30Z","timestamp":1680515070000},"source":"Crossref","is-referenced-by-count":3,"title":["Avalia\u00e7\u00e3o do desenvolvimento tecnol\u00f3gico em sa\u00fade a partir da ocorr\u00eancia das epidemias de zika e chikungunya no Brasil"],"prefix":"10.1590","volume":"39","author":[{"given":"Maria da Concei\u00e7\u00e3o Rodrigues","family":"Fernandes","sequence":"first","affiliation":[{"name":"Universidade Federal Rural do Semi-\u00c1rido,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Washington Sales do","family":"Monte","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural do Semi-\u00c1rido,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Silvestre Brilhante","family":"Bezerra","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural do Semi-\u00c1rido,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2023]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"e101","DOI":"10.1016\/S1473-3099(16)30518-7","article-title":"Epidemic arboviral diseases priorities for research and public health","volume":"17","author":"Wilder-Smith A","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.meegid.2018.11.009","article-title":"Aedes aegypti vector competence studies a review","volume":"67","author":"Souza-Neto JA","year":"2019","journal-title":"Infect Genet Evol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1139\/cjm-2019-0331","article-title":"Zika virus an emerging challenge to public health worldwide","volume":"66","author":"Sharma V","year":"2020","journal-title":"Can J Microbiol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"e119","DOI":"10.1016\/S1473-3099(16)30010-X","article-title":"Zika virus history of a newly emerging arbovirus","volume":"16","author":"Wikan N","year":"2016","journal-title":"Lancet Infect Dis"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/0035-9203(55)90080-8","article-title":"An epidemic of virus disease in Southern Province, Tanganyika territory, in 1952-1953","volume":"49","author":"Robinson MC","year":"1955","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1146\/annurev-virology-091919-102021","article-title":"New insights into chikungunya virus infection and pathogenesis","volume":"8","author":"Kril V","year":"2021","journal-title":"Annu Rev Virol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"4090","DOI":"10.1002\/jmv.26952","article-title":"Chikungunya and COVID-19 in Brazil the danger of an overlapping crises","volume":"93","author":"Jain S","year":"2021","journal-title":"J Med Virol"},{"key":"ref8","series-title":"Chikungunya worldwide overview 2022."},{"key":"ref9","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1097\/QCO.0000000000000775","article-title":"Global health security as it pertains to Zika, Ebola, and COVID-19","volume":"34","author":"Pannu J","year":"2021","journal-title":"Curr Opin Infect Dis"},{"key":"ref10","first-page":"1200","article-title":"IP preparedness for outbreak diseases","volume":"5","author":"Rutschman AS","year":"2018","journal-title":"UCLA Law Review"},{"key":"ref11","series-title":"Integrated risk of pandemic: Covid-19 impacts, resilience and recommendations","first-page":"345","volume-title":"Technological advancement and pandemic","author":"Kumar N","year":"2020"},{"key":"ref12","first-page":"145","article-title":"Propriedade intelectual em um mundo globalizado","volume":"5","author":"Buainain AM","year":"2010","journal-title":"Parcerias Estrat\u00e9gicas"},{"key":"ref13","first-page":"529","article-title":"Patents as surrogates for inimitable and non-substitutable resources","volume":"30","author":"Markman GD","year":"2004","journal-title":"J Manage"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"44","DOI":"10.7748\/ns.29.31.44.e8681","article-title":"Quantitative research","volume":"29","author":"Watson R","year":"2015","journal-title":"Nurs Stand"},{"key":"ref15","series-title":"Cortellis Drug Discovery Intelligence."},{"key":"ref16","series-title":"Consultas."},{"key":"ref17","series-title":"V\u00edrus Zika no Brasil. 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