{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:21:03Z","timestamp":1783693263695,"version":"3.55.0"},"reference-count":66,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006506","name":"Minist\u00e9rio da Sa\u00fade","doi-asserted-by":"crossref","award":["TED 1.2022"],"award-info":[{"award-number":["TED 1.2022"]}],"id":[{"id":"10.13039\/501100006506","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100006507","name":"Funda\u00e7\u00e3o Oswaldo Cruz","doi-asserted-by":"crossref","award":["TED 1.2022"],"award-info":[{"award-number":["TED 1.2022"]}],"id":[{"id":"10.13039\/501100006507","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cad. Sa\u00fade P\u00fablica"],"abstract":"<jats:p>Nos \u00faltimos anos, a acelerada expans\u00e3o do mercado de produtos de Cannabis medicinal (PCM) levou ao aumento do consumo e das demandas judiciais pleiteando PCM no Brasil. O objetivo do estudo foi analisar as indica\u00e7\u00f5es terap\u00eauticas presentes nas demandas judiciais que pleiteiam PCM, ajuizadas contra a Uni\u00e3o, e frente \u00e0s evid\u00eancias cient\u00edficas presentes na literatura. Foi realizado um estudo transversal, analisando-se processos referentes aos pleitos depositados entre 2020 e 2023, e executada uma s\u00edntese qualitativa r\u00e1pida de evid\u00eancias (SQRE) relacionada \u00e0s indica\u00e7\u00f5es da Cannabis medicinal apontadas nos processos. Nas 2.024 demandas, foram identificados 1.962 diagn\u00f3sticos prim\u00e1rios, sendo epilepsias (36,24%), transtorno do espectro autista (TEA) (25,54%) e dor (8,92%) as condi\u00e7\u00f5es mais frequentes. Observou-se alta frequ\u00eancia de demandantes no intervalo et\u00e1rio de 1 a 19 anos para epilepsia, TEA, paralisias e defici\u00eancia intelectual. Na SQRE, foram resgatadas 115 revis\u00f5es com emprego de ferramentas de avalia\u00e7\u00e3o de qualidade, que traziam informa\u00e7\u00f5es sobre a efetividade de PCM, apontando dor (40,86%), neoplasia (10,43%) e epilepsia (9,56%) como condi\u00e7\u00f5es mais estudadas. Para apenas cinco diagn\u00f3sticos - epilepsia, esclerose m\u00faltipla, ansiedade, neoplasia e dor - houve algum suporte na literatura, em graus diferentes, e com frequ\u00eancia baixa de revis\u00f5es de alta qualidade. A grande press\u00e3o da judicializa\u00e7\u00e3o e a quantidade de indica\u00e7\u00f5es sem evid\u00eancias destacam um risco sanit\u00e1rio consider\u00e1vel que n\u00e3o tem tido abordagem tempestiva no pa\u00eds. \u00c9 urgente a regulamenta\u00e7\u00e3o dos PCM e sua prescri\u00e7\u00e3o apropriada, resguardando o fornecimento p\u00fablico apenas \u00e0quelas baseadas em evid\u00eancias robustas.<\/jats:p>","DOI":"10.1590\/0102-311xpt220525","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:11:42Z","timestamp":1783692702000},"source":"Crossref","is-referenced-by-count":0,"title":["Indica\u00e7\u00f5es terap\u00eauticas em demandas judiciais por Cannabis medicinal no Brasil: um estudo transversal perante as evid\u00eancias cient\u00edficas"],"prefix":"10.1590","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5478-4977","authenticated-orcid":false,"given":"Cl\u00e1udia Du Bocage Santos","family":"Pinto","sequence":"first","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9857-9852","authenticated-orcid":false,"given":"Tatiana De Jesus Nascimento","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0464-1476","authenticated-orcid":false,"given":"Catia Veronica dos Santos","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7473-8636","authenticated-orcid":false,"given":"\u00c2ngela","family":"Esher","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9907-0619","authenticated-orcid":false,"given":"Marina Fajardo Villela Martins Pompilho da","family":"Hora","sequence":"additional","affiliation":[{"name":"Universidade do Estado do Rio de Janeiro,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4875-7216","authenticated-orcid":false,"given":"Claudia Garcia Serpa","family":"Osorio-de-Castro","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2026]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"11258","DOI":"10.3390\/ijms252011258","article-title":"Cannabis-based phytocannabinoids overview, mechanism of action, therapeutic application, production, and affecting environmental factors","volume":"25","author":"Jurga 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pain","volume":"7","author":"Barnes MP","year":"2006","journal-title":"Expert Opin Pharmacother"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1001\/jamapsychiatry.2018.2503","article-title":"Association of cannabinoid administration with experimental pain in healthy adults a systematic review and meta-analysis","volume":"75","author":"De Vita MJ","year":"2018","journal-title":"JAMA Psychiatry"},{"key":"ref42","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.43848","article-title":"Placebo response and media attention in randomized clinical trials assessing cannabis-based therapies for pain a systematic review and meta-analysis","volume":"5","author":"Gedin F","year":"2022","journal-title":"JAMA Netw Open"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"107559","DOI":"10.1016\/j.eplepsyres.2025.107559","article-title":"Cannabis derivatives and their synthetic analogs for treatment-resistant epilepsy a systematic review and meta-analysis","volume":"214","author":"Martimbianco ALC","year":"2025","journal-title":"Epilepsy Res"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1080\/08039488.2024.2381541","article-title":"Cannabinoids as alleviating treatment for core symptoms of autism spectrum disorder in children and adolescents a systematic review","volume":"78","author":"Ibsen EWD","year":"2024","journal-title":"Nord J Psychiatry"},{"key":"ref45","first-page":"20552173241282379","article-title":"Cannabinoids for spasticity in patients with multiple sclerosis A systematic review and meta-analysis","volume":"10","author":"Azadvari M","year":"2024","journal-title":"Mult Scler J Exp Transl Clin"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.clinthera.2025.07.009","article-title":"Assessing the role of cannabis in managing spasticity in multiple sclerosis a systematic review and meta-analysis","volume":"48","author":"AlHabil Y","year":"2026","journal-title":"Clin Ther"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"1521792","DOI":"10.3389\/fphar.2025.1521792","article-title":"Therapeutic potential of cannabinoids in neurological conditions a systematic review of clinical trials","volume":"16","author":"Hakami AY","year":"2025","journal-title":"Front Pharmacol"},{"key":"ref48","series-title":"Living systematic review on cannabis and other plant-based treatments for chronic pain: 2025 update","author":"Chou R","year":"2025"},{"key":"ref49","article-title":"Cannabinoids for the prevention of chemotherapy-induced nausea and vomiting in oncological therapy: a systematic review.","author":"Kemmner SF","year":"2025","journal-title":"J Cancer Surviv"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1055\/a-2262-7837","article-title":"Cannabinoids for behavioral symptoms in dementia an overview","volume":"57","author":"Broers 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review","volume":"15","author":"Leen NA","year":"2024","journal-title":"Front Pharmacol"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/s43441-021-00346-0","article-title":"Real world evidence in medical cannabis research","volume":"56","author":"Banerjee R","year":"2022","journal-title":"Ther Innov Regul Sci"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1467-9566.2012.01476.x","article-title":"The medicalisation of revolt a sociological analysis of medical cannabis users","volume":"35","author":"Pedersen W","year":"2013","journal-title":"Sociol Health Illn"},{"key":"ref56","first-page":"627","article-title":"Cannabinoids in pain management and palliative medicine","volume":"114","author":"H\u00e4user W","year":"2017","journal-title":"Dtsch \u00c4rztebl Int"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1001\/jama.2025.19433","article-title":"Therapeutic use of cannabis and cannabinoids a 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Dever do Estado de fornecer medicamento de alto custo a portador de doen\u00e7a grave que n\u00e3o possui condi\u00e7\u00f5es financeiras para compr\u00e1-lo."},{"key":"ref60","series-title":"Nota Informativa SMS\/SEABEVS n\u00ba 01\/2025. Orienta\u00e7\u00f5es para os servi\u00e7os de sa\u00fade e para os profissionais de sa\u00fade da rede municipal especializada do munic\u00edpio de S\u00e3o Paulo."},{"key":"ref61","article-title":"Lei n\u00ba 10.201, de 5 de dezembro de 2023. 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