{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T00:10:06Z","timestamp":1649117406107},"reference-count":28,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ABCD, arq. bras. cir. dig."],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:p>ABSTRACT  Background:  The influence of Helicobacter pylori (HP) in inflammatory disorders of the digestive mucosa has been the subject of several studies since socioeconomic, personal and environmental factors were implicated in the bacteria transmission.  Aim:  To correlate the inflammatory endoscopic findings with HP infection and the onset of mucosal diseases mucous of the upper digestive tract.  Method:  Comparative observational study, in which were collected data from 2247 patients who underwent upper endoscopy and biopsies for HP with urease test. The patients were divided into two groups: HP+ and HP- (control) in which endoscopic findings were observed for the following changes: esophagitis, esophageal ulcer, gastritis, erosive gastritis, gastric ulcer, bulboduodenitis, bulbar ulcer and without disease.  Results:  As for esophagitis, there was little disparity in the distribution favorable to HP+ group (HP+ =67.11% and HP- =69.89%) and esophageal ulcer (HP+ =0% and HP- =0, 21%). Gastritis was favorable to HP- group (HP+ =78.34% and HP- =73.63%), as well as erosive gastritis (HP+ = 67,11% and HP- = 64,55%), in bulboduodenitis (HP+ =1,87% and HP- 1,23%), in gastric ulcer (HP+ =2,14% and HP- =2,03%) and in the absence of alterations in the HP+ group (4.81%) with the HP- control group (6,30%), in which there was little disproportion in favor of HP- group, but without statistical significance. As for the bulbar ulcer (HP +=10.16% and HP- =4.48%), there was statistically significant (p=0.00001).  Conclusion:  There is no difference between HP+ and HP- groups in inflammatory changes in endoscopic gastroduodenal mucosa, except for the relationship between HP and bulbar ulcer.<\/jats:p>","DOI":"10.1590\/0102-6720201600030004","type":"journal-article","created":{"date-parts":[[2016,10,15]],"date-time":"2016-10-15T21:35:14Z","timestamp":1476567314000},"page":"142-145","source":"Crossref","is-referenced-by-count":0,"title":["RELATIONSHIP BETWEEN THE PRESENCE OF HELICOBACTER PYLORI WITH INFLAMMATORY ENDOSCOPIC CHANGES IN GASTRODUODENAL MUCOSA"],"prefix":"10.1590","volume":"29","author":[{"given":"Irma Cl\u00e1udia Saboya","family":"RIBEIRO","sequence":"first","affiliation":[{"name":"University Evangelic Hospital of Curitiba,  Brazil; 9 of July Hospital, S\u00e3o Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Fernandao","family":"KUBRUSLY","sequence":"additional","affiliation":[{"name":"University Evangelic Hospital of Curitiba,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Afonso Nunes","family":"NASSIF","sequence":"additional","affiliation":[{"name":"University Evangelic Hospital of Curitiba,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia Fernanda Saboya","family":"RIBEIRO","sequence":"additional","affiliation":[{"name":"9 of July Hospital, S\u00e3o Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo de Oliveira","family":"VERAS","sequence":"additional","affiliation":[{"name":"University Evangelic Hospital of Curitiba,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline","family":"NEPPEL","sequence":"additional","affiliation":[{"name":"University Evangelic Hospital of Curitiba,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"617","DOI":"10.3109\/07853899509002480","article-title":"What are the specific features of Helicobacter pylori gastritis in Children","volume":"27","author":"Ashorn M","year":"1995","journal-title":"Ann Med"},{"issue":"3","key":"ref2","first-page":"255","article-title":"Helicobacterpylori e doen\u00e7a p\u00e9ptica Estudo comparativo de m\u00e9todos diagn\u00f3sticos. Arq","volume":"45","author":"Caetano A","year":"2008","journal-title":"Gastroenterol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1046\/j.1365-2036.2003.01665.x","article-title":"Meta-analysis the relationship between Helicobacter pylori infection and gastrooesophageal reflux disease","volume":"18","author":"Cremonini F","year":"2003","journal-title":"Aliment PharmacolTher"},{"issue":"2","key":"ref4","first-page":"96","article-title":"Fatores associados com a gastrite cr\u00f4nica em pacientes com presen\u00e7a ou aus\u00eancia do Helicobacterpylori","volume":"25","author":"Ddine LC","year":"2012","journal-title":"ArqBrasCirDig"},{"issue":"1","key":"ref5","first-page":"3","article-title":"Altera\u00e7\u00f5es no teste ultra-r\u00e1pido da ur\u00e9ase e no exame anatomopatol\u00f3gico para Helicobacterpylori induzidas por drogas anti-secretoras","volume":"38","author":"Ferreira LEVVC","year":"2001","journal-title":"ArqGastroenterol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1016\/j.humpath.2010.04.010","article-title":"Gastric foveolar metaplasia and gastric heterotopia in the duodenum: no evidence of an etiologic role for Helicobacter pylori","volume":"41","author":"Genta RM","year":"2010","journal-title":"Hum Pathol"},{"issue":"suppl1","key":"ref7","first-page":"3","article-title":"Review article natural history and epidemology of Helicobacter pylori infection","volume":"16","author":"Go MF","year":"2002","journal-title":"AlimentPharmacolTher"},{"issue":"1","key":"ref8","first-page":"33","article-title":"Helicobacterpylori fatores relacionados a sua patog\u00eanese","volume":"22","author":"Guimaraes J","year":"2008","journal-title":"Revista Paraense de Medicina"},{"key":"ref9","first-page":"959","article-title":"Helicobacter pylori infection is the major risk factor for atrophic gastritis","volume":"51","author":"Kawaguchi H","year":"1996","journal-title":"Am JGastroenterol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1136\/gut.45.4.499","article-title":"Heterogeneity in the Helicobacter pylorivacA and cagA genes association with gastroduodenal disease in south Africa?","volume":"45","author":"Kidd M","year":"1999","journal-title":"Gut"},{"issue":"3","key":"ref11","first-page":"356","article-title":"Aspectos epidemiol\u00f3gicos do Helicobacterpylori na inf\u00e2ncia e adolesc\u00eancia Rev Sa\u00fade","volume":"36","author":"Kodaira MS","year":"2002","journal-title":"P\u00fablica"},{"key":"ref12","series-title":"Preval\u00eancia de infec\u00e7\u00e3o pelo Helicobacterpylori associada \u00e0s afec\u00e7\u00f5es diagnosticadas por endoscopia digestiva alta: an\u00e1lise retrospectiva de 1478 casos","author":"Marques SB","year":"2009"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s10620-014-3285-1","article-title":"Impact of Microscopic Duodenitis on Symptomatic Response to Helicobacter pylori Eradication in Functional Dyspepsia","volume":"60","author":"Mirbagheri SS","year":"2015","journal-title":"Dig Dis Sci"},{"key":"ref14","first-page":"1406","article-title":"Increased gastric epithelial cell apoptosis associated with colonization with CagA+ Helicobacter pylori strains","volume":"61","author":"Moss SF","year":"2001","journal-title":"Cancer Res"},{"issue":"2","key":"ref15","first-page":"93","article-title":"Preval\u00eancia da infec\u00e7\u00e3o por Helicobacterpylori e das les\u00f5es precursoras do c\u00e2ncer g\u00e1strico em pacientes disp\u00e9pticos","volume":"44","author":"Muller LB","year":"2007","journal-title":"ArqGastroenterol"},{"key":"ref16","first-page":"647","article-title":"Helicobacterpylorigenotypesmay determine gastrichistopathology","volume":"158","author":"Nogueira C","year":"2001","journal-title":"Am J Pathol"},{"key":"ref17","first-page":"7","article-title":"High degree of duodenal inflammation in Nigerians with functional dyspepsia","volume":"7","author":"Nwokediuko SC","year":"2013","journal-title":"ClinExpGastroenterol"},{"issue":"1","key":"ref18","first-page":"20","article-title":"Minimal endoscopic changes in non-erosive reflux disease","volume":"28","author":"Ratin ACF","year":"2015","journal-title":"ArqBrasCirDig,"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1016\/0140-6736(90)91301-P","article-title":"Cure of duodenal ulcer associated with eradication of Helicobacter pylori","volume":"335","author":"Rauws EAJ","year":"1990","journal-title":"Lancet"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0002-9343(01)00723-9","article-title":"The association between CagA status and the development of esophagitis after the eradication of Helicobacter pylori","volume":"110","author":"Rokkas T","year":"2001","journal-title":"Am J Med"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1046\/j.1365-2036.2003.01428.x","article-title":"Review article Helicobacter pylori and reflux disease","volume":"17","author":"Sharma P","year":"2003","journal-title":"Aliment PharmacolTher"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nrgastro.2013.9","article-title":"Helicobacter pylori infection in functional dyspepsia","volume":"10","author":"Suzuki H","year":"2013","journal-title":"Nat Rev GastroenterolHepatol"},{"key":"ref23","first-page":"107","article-title":"Helicobacter pylori eradication may induce de novo, but transient and mild, reflux esophagitis: prospective endoscopic evaluation","volume":"24","author":"Take S","year":"2009","journal-title":"J GastroenterolHepatol"},{"issue":"9","key":"ref24","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1111\/j.1572-0241.2000.02305.x","article-title":"CagApositive strains of Helicobacter pylori may protect against Barrett's esophagus","volume":"95","author":"Vaezi MF","year":"2000","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"ref25","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S0016-5085(98)70364-6","article-title":"The seroprevalence of cagApositiveHelicobacter pylori strains in the spectrum of gastroesophageal reflux disease","volume":"115","author":"Vicari JJ","year":"1998","journal-title":"Gastroenterology"},{"issue":"4","key":"ref26","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1590\/S0102-67202014000400017","article-title":"Nutritional care in peptic ulcer","volume":"27","author":"Vomero ND","year":"2014","journal-title":"Arq Bras Cir Dig,"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1093\/trstmh\/tru029","article-title":"Helicobacter pylori status and associated gastroscopic diagnoses in a tertiary hospital endoscopy population in Rwanda","volume":"108","author":"Walker TD","year":"2014","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"1","key":"ref28","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1023\/A:1018841222856","article-title":"Helicobacterpylori infection has no role in the pathogenesis of reflux esophagitis","volume":"42","author":"Werdmuller BF","year":"1997","journal-title":"Dig Dis Sci"}],"container-title":["ABCD. Arquivos Brasileiros de Cirurgia Digestiva (S\u00e3o Paulo)"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/abcd\/v29n3\/0102-6720-abcd-29-03-00142.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,24]],"date-time":"2017-05-24T01:15:46Z","timestamp":1495588546000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0102-67202016000300142&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S0102-67202016000300142"],"URL":"https:\/\/doi.org\/10.1590\/0102-6720201600030004","relation":{},"ISSN":["0102-6720"],"issn-type":[{"value":"0102-6720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9]]}}}