{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T12:19:14Z","timestamp":1773922754295,"version":"3.50.1"},"reference-count":24,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ABCD, arq. bras. cir. dig."],"abstract":"<jats:p>ABSTRACT Background: Tissue diagnosis is required for gastric subepithelial lesions for differential diagnosis of GISTs. However, there has not been consensus about the best needle for EUS-guided sampling of these lesions. Aim: To evaluate the diagnostic yield of EUS-FNA for gastric subepithelial lesions of the proper muscle layer with large-bore 19 gauge needles. Methods: A prospectively maintained database was retrospectively reviewed to identify consecutive patients who underwent EUS-FNA with 19 and 22 gauge needles for gastric subepithelial lesions of the fourth endosonographic layer in a tertiary care referral center. EUS-FNA was performed by the same endosonographer, using the fanning technique, without on-site cytopathologist. Specimens were analysed through cell blocks by the same pathologist. Procedure results were categorized into diagnostic, defined as enough material for histopathology and immunohistochemistry, or nondiagnostic. Results: Eighty-nine patients (mean age: 59 years, 77% women) underwent 92 EUS-FNA with 19 (75) or 22 (17) gauge needles. Mean lesion size was 22.6 mm. Overall diagnostic yield was 88%. The diagnostic yield of 19 gauge was higher than that of 22 gauge needle (92%x70.6%; p=0.0410), and similar for lesions &gt;2 cm and &lt;2 cm (93.7%x90.7%; p=0.9563). The best performance for 19 gauge needles was obtained performing &lt;3 needle passes. Complication rate was 2.8%. Conclusions: Diagnostic yield of EUS-FNA with 19 gauge needles is 92% for gastric subepithelial lesions of the proper muscle layer. It is safe and highly valuable for differentiation between GIST and leiomyoma, no matter the size of the lesion.<\/jats:p>","DOI":"10.1590\/0102-672020180001e1350","type":"journal-article","created":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T19:46:28Z","timestamp":1530128788000},"source":"Crossref","is-referenced-by-count":12,"title":["EUS-FNA WITH 19 OR 22 GAUGES NEEDLES FOR GASTRIC SUBEPITHELIAL LESIONS OF THE MUSCLE LAYER"],"prefix":"10.1590","volume":"31","author":[{"given":"C\u00e9sar Vivian","family":"LOPES","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Digestive Endoscopy, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Atal\u00edbio","family":"HARTMANN","sequence":"additional","affiliation":[{"name":"Santa Casa Hospital, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Everson Luiz de Almeida","family":"ARTIFON","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2018,6,21]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.15403\/jgld.2014.1121.234.eug","article-title":"Clinical usefulness of endoscopic ultra-soundguided fine needle aspiration for gastric subepithelial lesions smaller than 2 cm","volume":"23","author":"Akahoshi K","year":"2014","journal-title":"J Gastrointestin Liver Dis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.7863\/jum.2004.23.9.1141","article-title":"Endoscopic sonographically guided fine-needle aspiration yield in submucosal tumors of the gastrointestinal tract","volume":"23","author":"Arantes V","year":"2004","journal-title":"J Ultrasound Med"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"AB 423","DOI":"10.1016\/j.gie.2014.02.576","article-title":"Gastrointestinal Stromal Tumors: a Sys-tematic Review of Diagnostic 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patients with gastric submucosal tumors a prospective study","volume":"41","author":"Polkowski M","year":"2009","journal-title":"Endoscopy"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1055\/s-0031-1291543","article-title":"Learning, techniques, and complica-tions of endoscopic ultrasound (EUS)-guided sampling in gastroenterology European Society of Gastrointestinal Endoscopy (ESGE) Technical Guideline","volume":"44","author":"Polkowski M","year":"2012","journal-title":"Endoscopy"},{"key":"ref21","first-page":"619128","article-title":"Factors associated with inadequate tissue yield in EUS-FNA for gastric SMT","author":"Suzuki T","year":"2011","journal-title":"ISRN Gastroenterol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1007\/s10620-011-1646-6","article-title":"Yield and performance characteris-tics of endoscopic ultrasound-guided fine needle aspiration for diagnosing upper GI tract stromal 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Arquivos Brasileiros de Cirurgia Digestiva (S\u00e3o Paulo)"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/abcd\/v31n1\/2317-6326-abcd-31-01-e1350.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,4]],"date-time":"2020-11-04T13:17:37Z","timestamp":1604495857000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0102-67202018000100311&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,21]]},"references-count":24,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018]]}},"alternative-id":["S0102-67202018000100311"],"URL":"https:\/\/doi.org\/10.1590\/0102-672020180001e1350","relation":{},"ISSN":["2317-6326","0102-6720"],"issn-type":[{"value":"2317-6326","type":"electronic"},{"value":"0102-6720","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6,21]]}}}