{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T12:25:47Z","timestamp":1774355147848,"version":"3.50.1"},"reference-count":18,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ABCD, arq. bras. cir. dig."],"abstract":"<jats:p>ABSTRACT  Background: It is important but difficult to treat complex fistula-in-ano due to the high recurrent rate and following incontinence. Ligation of the intersphincteric fistula tract (LIFT), a novel surgical procedure with the advantage of avoiding anal incontinence, has a variable success rate of 57-94.4 %.  Aim: To evaluate the long-term outcomes of modified LIFT operative procedure - ligation of intersphincteric fistula tract - to treat complex fistula-in-ano.  Methods: Retrospective analysis of 62 cases of complex fistula-in-ano. The group was treated with the modified approach of LIFT (curved incision was made in the anal canal skin; purse-string suture was performed around the fistula; the residual fistulas were removed in a tunnel-based way) and had a follow-up time of more than one year. Patient\u00b4s preoperative general condition, postoperative efficacy and their anal function were compared.  Results: The median age of the participants was 34, and 43 (69.4%) cases were male. Forty-one (66.1%) cases were of high transsphincteric fistula, four (6.5%) cases of high intrasphincter fistula, and 17 (27.4%) cases of anterior anal fistula in female. The median follow-up duration was 24.5 (range, 12-51) months. The success rate in the end of follow-up was 83.9% (52\/62). The anorectal pressure and Cleveland Clinic Florida Fecal Incontinence (CCF-FI) evaluated three months before and after the operation did not find apparent changes.  Conclusions:  Compared with LIFT, the modified LIFT remarkably reduces postoperative failure and the recurrence rate of complex fistula with acceptable long-term outcomes.<\/jats:p>","DOI":"10.1590\/0102-672020180001e1404","type":"journal-article","created":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T19:46:58Z","timestamp":1544125618000},"source":"Crossref","is-referenced-by-count":12,"title":["LONG-TERM OUTCOMES OF LIGATION OF INTERSPHINCTERIC FISTULA TRACT FOR COMPLEX FISTULA-IN-ANO: MODIFIED OPERATIVE PROCEDURE EXPERIENCE"],"prefix":"10.1590","volume":"31","author":[{"given":"Ke","family":"WEN","sequence":"first","affiliation":[{"name":"Nanjing University of Chinese Medicine,  China; Nanjing University of Chinese Medicine,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun-Fei","family":"GU","sequence":"additional","affiliation":[{"name":"Nanjing University of Chinese Medicine,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue-Liang","family":"SUN","sequence":"additional","affiliation":[{"name":"Nanjing University of Chinese Medicine,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Peng","family":"WANG","sequence":"additional","affiliation":[{"name":"Nanjing University of Chinese Medicine,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuai","family":"YAN","sequence":"additional","affiliation":[{"name":"Nanjing University of Chinese Medicine,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zong-Qi","family":"HE","sequence":"additional","affiliation":[{"name":"Nanjing University of Chinese Medicine,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu-Guang","family":"ZHEN","sequence":"additional","affiliation":[{"name":"Nanjing University of Chinese Medicine,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2018,12,6]]},"reference":[{"issue":"5","key":"ref1","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.amjsurg.2015.01.002","article-title":"Results from a novel modification to the ligation intersphincteric fistula tract","volume":"209","author":"Bastawrous A","year":"2015","journal-title":"Am J Surg"},{"issue":"53","key":"ref2","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1007\/DCR.0b013e3181ec4470","article-title":"Outcomes with the use of bioprosthetic grafts to reinforce the ligation of the intersphincteric fistula tract (BioLIFT procedure) for the management of complex anal fistulas","volume":"10","author":"Ellis CN","year":"2010","journal-title":"Dis Colon Rectum"},{"issue":"8","key":"ref3","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1007\/s00384-012-1437-3","article-title":"Quantifying the extent of fistulotomy How much sphincter can we safely divide? A three-dimensional endosonographic study","volume":"27","author":"Garc\u00eda-Botello SA","year":"2012","journal-title":"Int J Colorectal Dis"},{"key":"ref4","series-title":"The ASCRS Textbook of Colonand Rectal Surgery,","first-page":"245","volume-title":"Maher AA. Complex Anorectal Fistulas","author":"Giulio AS","year":"2016","edition":"3"},{"issue":"5","key":"ref5","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s00384-014-2091-8","article-title":"Systematic review and meta-analysis of surgical interventions for high cryptoglandular perianal fistula","volume":"30","author":"G\u00f6ttgens KW","year":"2015","journal-title":"Int J Colorectal Dis"},{"issue":"5","key":"ref6","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1111\/codi.12062","article-title":"Ligation of the intersphincteric fistula tract plus a bioprosthetic anal fistula plug (LIFT-Plug): a new technique for fistula-in-ano","volume":"15","author":"Han JG","year":"2013","journal-title":"Colorectal Dis"},{"issue":"8","key":"ref7","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s10151-014-1183-3","article-title":"Ligation of intersphincteric fistula tract (LIFT) to treat anal fistula systematic review and meta-analysis","volume":"18","author":"Hong KD","year":"2014","journal-title":"Tech Coloproctol"},{"issue":"1","key":"ref8","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/BF02050307","article-title":"Etiology and management of fecal incontinence","volume":"36","author":"Jorge JM","year":"1993","journal-title":"Dis Colon Rectum"},{"issue":"1","key":"ref9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/1117-6806.169818","article-title":"Management of Fistula-In-Ano with Special Reference to Ligation of Intersphincteric Fistula Tract","volume":"22","author":"Khadia M","year":"2016","journal-title":"Niger J Surg"},{"issue":"5","key":"ref10","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1111\/codi.12104","article-title":"Efficacy of LIFT for recurrent anal fistula","volume":"15","author":"Lehmann JP","year":"2013","journal-title":"Colorectal Dis"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1097\/DCR.0b013e318278164c","article-title":"long-term results of ligation of intersphincteric fistula tract (lift) for fistula-in-ano","volume":"56","author":"Liu WY","year":"2013","journal-title":"Dis Colon Rectum"},{"issue":"8","key":"ref12","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1002\/bjs.1800800853","article-title":"Histological and microbiological assessment of the role of microorganisms in chronic anal fistula","volume":"80","author":"Lunniss PJ","year":"1993","journal-title":"Br J Surg"},{"issue":"10","key":"ref13","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1097\/DCR.0000000000000880","article-title":"Ligation of Intersphincteric Fistula Tract for Fistula in Ano: Lessons Learned from a Decade of Experience","volume":"60","author":"Malakorn S","year":"2017","journal-title":"Dis Colon Rectum"},{"issue":"90","key":"ref14","first-page":"581","article-title":"Total anal sphincter saving technique for fistula-in-ano: the ligation of intersphincteric fistula tract","volume":"3","author":"Rojanasakul A","year":"2007","journal-title":"J Med Assoc Thai"},{"issue":"1","key":"ref15","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/DCR.0b013e3181c160c4","article-title":"Ligation of the intersphincteric fistula tract (LIFT) a sphincter-saving technique for fistula-in-ano","volume":"53","author":"Shanwani A","year":"2010","journal-title":"Dis Colon Rectum"},{"issue":"11","key":"ref16","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1097\/DCR.0b013e31822bb55e","article-title":"The anatomy of failures following the ligation of intersphincteric tract technique for anal fistula a review of 93 patients over 4 years","volume":"54","author":"Tan KK","year":"2011","journal-title":"Dis Colon Rectum"},{"issue":"5","key":"ref17","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/codi.12030","article-title":"Ligation of the intersphincteric fistula tract in low transsphincteric fistulae a new technique to avoid fistulotomy","volume":"15","author":"Van Onkelen RS","year":"2013","journal-title":"Colorectal Dis"},{"issue":"11","key":"ref18","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1097\/DCR.0b013e318266edf3","article-title":"Does ligation of the intersphincteric fistula tract raise the bar in fistula surgery","volume":"55","author":"Wallin UG","year":"2012","journal-title":"Dis Colon Rectum"}],"container-title":["ABCD. Arquivos Brasileiros de Cirurgia Digestiva (S\u00e3o Paulo)"],"original-title":[],"deposited":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T18:53:50Z","timestamp":1545418430000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0102-67202018000400304&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,6]]},"references-count":18,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018]]}},"alternative-id":["S0102-67202018000400304"],"URL":"https:\/\/doi.org\/10.1590\/0102-672020180001e1404","relation":{},"ISSN":["2317-6326","0102-6720"],"issn-type":[{"value":"2317-6326","type":"electronic"},{"value":"0102-6720","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12,6]]}}}