{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T22:43:49Z","timestamp":1773269029740,"version":"3.50.1"},"reference-count":36,"publisher":"FapUNIFESP (SciELO)","issue":"2","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ABCD, arq. bras. cir. dig."],"abstract":"<jats:p>ABSTRACT   Background:  Extended vertical gastrectomy is a variation of the vertical gastrectomy technique requiring studies to elucidate safety in relation to gastroesophageal reflux.   Aim:  To analyze comparatively vertical gastrectomy (VG) and extended vertical gastrectomy (EVG) in rats with obesity induced by cafeteria diet in relation to the presence of reflux esophagitis, weight loss and macroscopic changes related to the procedures.   Methods:  Thirty Wistar rats were randomized into three groups, and after the obesity induction period by means of a 28-day cafeteria diet, underwent a simulated surgery (CG), VG and VGA. The animals were followed up for 28 days in the post-operative period, and after euthanasia, the reflux esophagitis evaluation was histopathologically performed. Weight and macroscopy were the other variables; weight was measured weekly and the macroscopic evaluation was performed during euthanasia.  Results: All animals presented some degree of inflammation and the presence of at least one inflammation criterion; however, there was no statistically significant difference in the analysis among the groups. In relation to weight loss, the animals in CG showed a gradual increase during the whole experiment, evolving to super-obesity at the end of the study, while the ones with VG and EVG had weight regain after the first post-operative period; however, a less marked regain compared to CG, both for VG and EVG.   Conclusion:  There is no difference in relation to reflux esophagitis VG and EVG, as well as macroscopic alterations, and both techniques have the ability to control the evolution of weight during postoperative period in relation to CG.<\/jats:p>","DOI":"10.1590\/0102-672020190001e1513","type":"journal-article","created":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T20:34:48Z","timestamp":1598301288000},"source":"Crossref","is-referenced-by-count":5,"title":["VERTICAL GASTRECTOMY VS. EXTENDED VERTICAL GASTRECTOMY: WHAT IS THE IMPACT ON GASTROESOPHAGEAL REFLUX DISEASE IN OBESE RATS?"],"prefix":"10.1590","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9783-898X","authenticated-orcid":false,"given":"Jos\u00e9 Aparecido","family":"VALAD\u00c3O","sequence":"first","affiliation":[{"name":"Evangelic Mackenzie Faculty of Paran\u00e1,  Brazil; Federal University of Maranh\u00e3o,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1336-8528","authenticated-orcid":false,"given":"Plinio da Cunha","family":"LEAL","sequence":"additional","affiliation":[{"name":"Federal University of Maranh\u00e3o,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0883-4774","authenticated-orcid":false,"given":"Eduardo Jos\u00e9 Silva Gomes de","family":"OLIVEIRA","sequence":"additional","affiliation":[{"name":"Federal University of Maranh\u00e3o,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7398-5395","authenticated-orcid":false,"given":"Orlando Jorge Martins","family":"TORRES","sequence":"additional","affiliation":[{"name":"Federal University of Maranh\u00e3o,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5544-8641","authenticated-orcid":false,"given":"Luis Eduardo Veras","family":"PINTO","sequence":"additional","affiliation":[{"name":"Presidente Dutra University Hospital,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5577-2815","authenticated-orcid":false,"given":"Danilo Dallago De","family":"MARCHI","sequence":"additional","affiliation":[{"name":"Zilberstein Institute,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5669-4169","authenticated-orcid":false,"given":"Ozimo Pereira","family":"GAMA-FILHO","sequence":"additional","affiliation":[{"name":"Federal University of Maranh\u00e3o,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7813-6210","authenticated-orcid":false,"given":"Marco Aurelio","family":"SANTO","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1752-5837","authenticated-orcid":false,"given":"Paulo Afonso Nunes","family":"NASSIF","sequence":"additional","affiliation":[{"name":"Evangelic Mackenzie Faculty of Paran\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2020]]},"reference":[{"issue":"4","key":"ref1","doi-asserted-by":"crossref","DOI":"10.1590\/0102-672020190001e1474","article-title":"Weight loss comparison after sleeve and roux-en-y gastric bypass: systematic review","volume":"32","author":"Barros F","year":"2019","journal-title":"Arq Bras Cir Dig"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/s11695-011-0528-5","article-title":"Carbohydrate content of post-operative diet influences the effect of vertical sleeve gastrectomy on body weight reduction in obese rats","volume":"22","author":"Bielohuby M","year":"2012","journal-title":"Obes Surg"},{"issue":"3","key":"ref3","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.amjmed.2008.09.041","article-title":"Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis","volume":"122","author":"Buchwald H","year":"2009","journal-title":"Am J Med"},{"issue":"4","key":"ref4","doi-asserted-by":"crossref","first-page":"E424","DOI":"10.1152\/ajpendo.00469.2013","article-title":"Regulation of gastric emptying rate and its role in nutrient-induced GLP-1 secretion in rats after vertical sleeve 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