{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T04:33:22Z","timestamp":1766810002009},"reference-count":15,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. Dent. J."],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:p>Periodontal disease is ranked among the 10 most prevalent chronic diseases worldwide, and is considered a major public health problem. Its etiology has been associated with local and general conditions that could interfere in the host immune response. Obesity, like periodontal disease, has emerged as a prevalent chronic disease in high-, low- and medium-income countries, recognized as risk factor for cardiovascular disease and cancer. A relationship between periodontal health and obesity may exist, but the mechanism that would explain this association remains unclear. Life-course epidemiology could be a useful instrument to investigate a casual association between early exposures and later outcomes, being appropriate for understanding the establishment of chronic conditions. This approach comprehends different theories, considering the time, the duration and the intensity of early exposition, and its impact on the development of chronic diseases in later life. Thus, the aim of this study is to hypothesize the different life-course epidemiology theories to explain the possible association between periodontal health and nutritional status in adulthood.<\/jats:p>","DOI":"10.1590\/0103-6440201300019","type":"journal-article","created":{"date-parts":[[2014,8,16]],"date-time":"2014-08-16T14:54:50Z","timestamp":1408200890000},"page":"87-89","source":"Crossref","is-referenced-by-count":19,"title":["Relationship Between Periodontal Disease and Obesity: The Role of Life-Course Events"],"prefix":"10.1590","volume":"25","author":[{"given":"Gustavo G.","family":"Nascimento","sequence":"first","affiliation":[{"name":"Federal University of Pelotas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F\u00e1bio R.","family":"Leite","sequence":"additional","affiliation":[{"name":"Federal University of Pelotas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos B.","family":"Correa","sequence":"additional","affiliation":[{"name":"Federal University of Pelotas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernardo L.","family":"Horta","sequence":"additional","affiliation":[{"name":"Federal University of Pelotas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco A.","family":"Peres","sequence":"additional","affiliation":[{"name":"The University of Adelaide,  Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fl\u00e1vio F.","family":"Demarco","sequence":"additional","affiliation":[{"name":"Federal University of Pelotas,  Brazil; Federal University of Pelotas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1600-0757.2012.00457.x","article-title":"Risk factors for periodontal disease","volume":"62","author":"Genco RJ","year":"2013","journal-title":"Periodontol 2000"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1600-0757.2011.00425.x","article-title":"The global burden of periodontal disease: towards integration with chronic disease prevention and control","volume":"60","author":"Petersen PE","year":"2012","journal-title":"Periodontol 2000"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1600-0757.2012.00452.x","article-title":"Periodontal health and global public health","volume":"60","author":"Petersen PE","year":"2012","journal-title":"Periodontol 2000"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1111\/jcpe.12088","article-title":"Infection and inflammatory mechanisms","volume":"40","author":"Van Dyke TE","year":"2013","journal-title":"J Clin Periodontol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1111\/jcpe.12163","article-title":"Are obesity and overweight associated with gingivitis occurrence in Brazilian schoolchildren?","volume":"40","author":"Nascimento GG","year":"2013","journal-title":"J Clin Periodontol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1111\/jcpe.12146","article-title":"Metabolic syndrome and gingival inflammation in Caucasian children with a family history of obesity","volume":"40","author":"Ka K","year":"2013","journal-title":"J Clin Periodontol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1111\/j.1600-051X.2012.01906.x","article-title":"Association between obesity and periodontal disease in young adults: a population-based birth cohort","volume":"39","author":"Dickie de Castilhos E","year":"2012","journal-title":"J Clin Periodontol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1600-051X.2009.01515.x","article-title":"Visceral fat area-defined obesity and periodontitis among Koreans","volume":"37","author":"Han DH","year":"2010","journal-title":"J Clin Periodontol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1111\/j.1471-0528.2006.01004.x","article-title":"Is obesity an inflammatory illness? 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