{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T04:19:40Z","timestamp":1648959580763},"reference-count":12,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. Dent. J."],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:p>This paper presents a case of osteonecrosis of the jaw related to zoledronic acid (5                mg) administered once yearly to treat osteoporosis. A 79-year-old woman who has been                treated for osteoporosis for 5 years with 5 applications of zoledronic acid was                referred for evaluation. The patient had been submitted to dental implant placement                and there was no osseointegration. On clinical examination, suppuration and exposed                bone on the alveolar ridge were observed. Radiographic examination revealed an                osteolytic area and bone sequestration. Both clinical and radiological features were                suggestive of osteonecrosis. The treatment consisted of surgery to remove the                affected bone completely. The patient is asymptomatic at 9 months after surgery.                Dentists and oral surgeons should be alert to the possibility of osteonecrosis                related to the use of once-yearly injections of zoledronic acid for the treatment of                postmenopausal osteoporosis.<\/jats:p>","DOI":"10.1590\/0103-6440201300255","type":"journal-article","created":{"date-parts":[[2015,2,7]],"date-time":"2015-02-07T20:15:57Z","timestamp":1423340157000},"page":"86-88","source":"Crossref","is-referenced-by-count":2,"title":["Osteonecrosis Related to Once-Yearly Zoledronic Acid Treatment in an                Osteoporotic Patient after Dental Implant"],"prefix":"10.1590","volume":"26","author":[{"given":"Thais Gimenez","family":"Miniello","sequence":"first","affiliation":[{"name":"AC Camargo Cancer Center,  Brazil; USP - University of S\u00e3o Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliane Pir\u00e1gine","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"USP - University of S\u00e3o Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo Nascimento","family":"Lopes","sequence":"additional","affiliation":[{"name":"AC Camargo Cancer Center,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio Abreu","family":"Alves","sequence":"additional","affiliation":[{"name":"AC Camargo Cancer Center,  Brazil; USP - University of S\u00e3o Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1359\/jbmr.0707onj","article-title":"American Society for Bone and Mineral Research.                   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