{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T09:24:00Z","timestamp":1780046640558,"version":"3.53.1"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. Dent. J."],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:p>Abstract The aim of this study was to evaluate the demographic and clinical profile of the oral squamous cells carcinoma (OSCC) cases registered in a center of oral diagnosis in southern Brazil. Eight hundred and six individuals with OSCC from 1959 to 2012 were included in this study. The variables recorded were: sex, age, occupation according to workplace, alcohol and tobacco consumption, skin color, tumor location, histological type, clinical appearance, size, evolution time, presence of pain and lymph node metastasis. Descriptive analysis was performed and the associations between variables were assessed using the chi-square and Fisher\u2019s exact test, with a confidence level of 5%. OSSC was more common in males (76.6%) aged between 51 to 70 years (53.9%). The most frequent sites were lower lip vermilion (23.3%), tongue (20.2%) and gingiva\/alveolar ridge (18.1%). There was a strong association between outdoor occupation and white skin color with lip squamous cell carcinoma (LSCC). OSCC intraoral lesions were commonly more painful, larger than 2 cm and presented lymphatic metastasis. In conclusion, most of the results confirm the data from literature about sex, age, tumor location and occupation. Moreover, the positive correlations between LSCC and occupation, between LSCC and white skin color, and between bigger lesions and presence of pain\/cervical metastasis also corroborate the literature data.<\/jats:p>","DOI":"10.1590\/0103-6440201601257","type":"journal-article","created":{"date-parts":[[2017,8,2]],"date-time":"2017-08-02T18:21:00Z","timestamp":1501698060000},"page":"301-306","source":"Crossref","is-referenced-by-count":27,"title":["Demographic and Clinical Profile of Oral Squamous Cell Carcinoma from a Service-Based Population"],"prefix":"10.1590","volume":"28","author":[{"given":"Alessandro Menna","family":"Alves","sequence":"first","affiliation":[{"name":"Universidade Federal de Pelotas,  Brazil; Universidade Federal de Pelotas,  Brazil; UNIVATES - Unidade Integrada Vale do Taquari de Ensino Superior,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos Britto","family":"Correa","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pelotas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karine Duarte da","family":"Silva","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pelotas,  Brazil; Universidade Federal de Pelotas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenita Maria Aver de","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pelotas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Carolina Uchoa","family":"Vasconcelos","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pelotas,  Brazil; Universidade Federal de Pelotas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Paula Neutzling","family":"Gomes","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pelotas,  Brazil; Universidade Federal de Pelotas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Etges","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pelotas,  Brazil; Universidade Federal de Pelotas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra Beatriz Chaves","family":"Tarquinio","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pelotas,  Brazil; Universidade Federal de Pelotas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1002\/hed.20573","article-title":"Current topics in the epidemiology of oral cavity and oropharyngeal cancers","volume":"29","author":"Gillison ML","year":"2007","journal-title":"Head Neck"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.oraloncology.2008.06.002","article-title":"Global epidemiology of oral and oropharyngeal cancer","volume":"45","author":"Warnakulasuriya S","year":"2009","journal-title":"Oral Oncol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1600-0757.2011.00401.x","article-title":"Squamous cell carcinoma and precursor lesions of the oral cavity: epidemiology and aetiology","volume":"57","author":"Johnson NW","year":"2000","journal-title":"Periodontol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1007\/s10552-011-9779-7","article-title":"Alcohol and tobacco, and the risk of cancers of the upper aerodigestive tract in Latin America: a case-control study","volume":"22","author":"Szymanska K","year":"2011","journal-title":"Cancer Causes Control"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1038\/sj.bjc.6606091","article-title":"Head and neck cancer in Australia between 1982 and 2005 show increasing incidence of potentially HPV-associated oropharyngeal cancers","volume":"104","author":"Hocking JS","year":"2011","journal-title":"Br J Cancer"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1200\/JCO.2010.31.7883","article-title":"Increasing incidence of oral tongue squamous cell carcinoma in young white women, age 18 to 44 years","volume":"29","author":"Patel SC","year":"2011","journal-title":"J Clin Oncol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1093\/aje\/kwr468","article-title":"Associations between dietary patterns and head and neck cancer: the Carolina head and neck cancer epidemiology study","volume":"175","author":"Bradshaw PT","year":"2012","journal-title":"Am J Epidemiol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1590\/1679-775720130317","article-title":"Oral squamous cell carcinoma: clinicopathological features from 346 cases from a single oral pathology service during an 8-year period","volume":"21","author":"Pires FR","year":"2013","journal-title":"J Appl Oral Sci"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"267","DOI":"10.2334\/josnusd.52.267","article-title":"Oral squamous cell carcinoma: an analysis of 1,564 cases showing advances in early detection","volume":"52","author":"Marocchio LS","year":"2010","journal-title":"J Oral Sci"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"e757","DOI":"10.4317\/medoral.16954","article-title":"Lip squamous cell carcinoma in a Brazilian population: epidemiological study and clinicopathological associations","volume":"16","author":"Souza RL","year":"2011","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"ref11","first-page":"30","article-title":"The effectiveness of the oral cancer prevention and early diagnosis program in Sao Paulo, Brazil","volume":"21","author":"Antunes JL","year":"2007","journal-title":"Rev Panam Salud Publica"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"S73","DOI":"10.1038\/sj.bjc.6605395","article-title":"Development and evaluation of an early detection intervention for mouth cancer using a mass media approach","volume":"101","author":"Eadie D","year":"2009","journal-title":"Br J Cancer"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1590\/S1806-83242010000500007","article-title":"Oral cancer public policies: is there any evidence of impact?","volume":"24","author":"Torres-Pereira C","year":"2010","journal-title":"Braz Oral Res"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1002\/ijc.2910100118","article-title":"An epidemiologic study of oral cancer and precancerous conditions among 101,761 villagers in Maharashtra, India","volume":"10","author":"Mehta FS","year":"1972","journal-title":"Int J Cancer"},{"key":"ref15","first-page":"155","article-title":"Factors associated with prevalence of oral lesions and oral self-examination in young adults from a birth cohort in Southern Brazil","volume":"29","author":"Correa MB","year":"2013","journal-title":"Cad Sa\u00fade 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