{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T15:04:06Z","timestamp":1761663846990},"reference-count":35,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. Dent. J."],"abstract":"<jats:p>Abstract This research aimed to determine the influence of fluoridated groundwater and 1,100 ppm fluoride dentifrice on biomarkers of exposure to fluoride in preschoolers. A cross-sectional study was performed on thirty preschoolers recruited from naturally fluoridated and non-fluoridated areas (n=15). Total Daily Fluoride Intake (TDFI) from diet and dentifrice, and Daily Urinary Fluoride Excretion (DUFE) was measured over 24 h. Nails samples were collected twice during 30 days. Fluoride analyses were performed using a fluoride-ion-specific electrode. Data were evaluated using the Student and paired t-test, Pearson correlation analysis, multiple linear regression analysis (\u03b1\u22640.05). Fluoridated groundwater and dentifrice were the dominant sources (r2 &gt; 0.83) of TDFI in children from a naturally fluoridated and a non-fluoridated area, respectively. A positive correlation between TDFI and DUFE (r=0.50), and between [F] in fingernails and toenails (r=0.60) were found in children from a naturally fluoridated area. The [F] in nails of finger and toe were not correlated to TDFI. The consumption of fluoridated groundwater influenced the fluoride concentration in urine. In addition, the use of 1,100 ppm fluoride dentifrice did not influence the fluoride concentration in urine and fingernails.<\/jats:p>","DOI":"10.1590\/0103-6440201801959","type":"journal-article","created":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T11:33:41Z","timestamp":1543577621000},"page":"475-482","source":"Crossref","is-referenced-by-count":6,"title":["Influence of Fluoridated Groundwater and 1,100 Ppm Fluoride Dentifrice on Biomarkers of Exposure to Fluoride"],"prefix":"10.1590","volume":"29","author":[{"given":"Emerson Tavares de","family":"Sousa","sequence":"first","affiliation":[{"name":"Universidade de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa Feitosa","family":"Alves","sequence":"additional","affiliation":[{"name":"Universidade Federal da Paraiba,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiana Barros Marinho","family":"Maia","sequence":"additional","affiliation":[{"name":"Universidade Federal da Paraiba,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marin\u00eas","family":"Nobre-dos-Santos","sequence":"additional","affiliation":[{"name":"Universidade de Campinas,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franklin Delano Soares","family":"Forte","sequence":"additional","affiliation":[{"name":"Universidade Federal da Paraiba,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F\u00e1bio Correia","family":"Sampaio","sequence":"additional","affiliation":[{"name":"Universidade Federal da Paraiba,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2018,9]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1007\/s10653-015-9769-x","article-title":"\u201cBorderline\u201d fluorotic region in Serbia: correlations among fluoride in drinking water, biomarkers of exposure and dental fluorosis in schoolchildren","volume":"38","author":"Antonijevic E","year":"2016","journal-title":"Environ Geochem Health"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1177\/00220345920710051601","article-title":"The changing patterns of systemic fluoride intake","volume":"71","author":"Burt BA","year":"1992","journal-title":"J Dent Res"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1159\/000279325","article-title":"Relationships between fluoride intake, urinary fluoride excretion and fluoride retention in children and adults: an analysis of available data","volume":"44","author":"Villa A","year":"2010","journal-title":"Caries Res"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.yrtph.2015.04.005","article-title":"Biomonitoring Equivalents for interpretation of urinary fluoride","volume":"72","author":"Aylward LL","year":"2015","journal-title":"Regul Toxicol Pharmacol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1038\/sj.bdj.2013.531","article-title":"Fluoride balance in infants and young children in the U.K. and its clinical relevance for the dental team","volume":"214","author":"Maguire A","year":"2013","journal-title":"Br Dent J"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/ipd.12108","article-title":"Total daily fluoride intake and the relative contributions of foods, drinks and toothpaste by 3- to 4-year-old children in the Gaza Strip - 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