{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T04:59:24Z","timestamp":1788325164344,"version":"build-2803163510"},"reference-count":37,"publisher":"FapUNIFESP (SciELO)","issue":"3","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. Dent. J."],"abstract":"<jats:p>Abstract This study aimed to quantify the penetration of hydrogen peroxide, color change evaluation, surface morphology, and composition after application of desensitizing agents before in-office bleaching. Fifty premolars were sectioned, an acetate buffer was placed in the pulp chamber and divided into five groups (n=10). In the positive control group, only the in-office bleaching gel was used, and in the negative control group, no treatment was used. Three different desensitizing agents were applied: Desensibilize KF2%\u00ae group; Mi Paste\u00ae group, and Desensibilize Nano-P\u00ae group. The bleaching procedure was carried out with 35% HP. The absorbance of the resulting solution was determined in a spectrophotometer. Color change was assessed by using a digital spectrophotometer. Four additional premolars were assigned to the same groups above for analysis under scanning electron microscope, as well as to evaluate the elemental composition with X-ray dispersive energy spectrometry. Data were subjected to ANOVA and Tukey's test (\u03b1=0.05). All products reduced the penetration of HP in the pulp chamber. Mi Paste and Nano P were the products that yielded the lowest HP penetration, which was similar to the negative control group (p&lt;0.001). No significant difference was detected in color change (p&lt;0.001). Concerning enamel morphology, the groups that were analyzed after bleaching were observed a greater deposition of desensitizing agents on the surface. The use of desensitizing agents before tooth bleaching seems to be an alternative to reduce adverse effects of the tooth.<\/jats:p>","DOI":"10.1590\/0103-6440202003365","type":"journal-article","created":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T13:13:21Z","timestamp":1594646001000},"page":"236-243","source":"Crossref","is-referenced-by-count":20,"title":["Effect of Prior Application of Desensitizing Agent on the Teeth Submitted to In-Office Bleaching"],"prefix":"10.1590","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1545-7663","authenticated-orcid":false,"given":"Sibelli Olivieri","family":"Parreiras","sequence":"first","affiliation":[{"name":"Universidade Estadual do Norte do Paran\u00e1,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0800-7915","authenticated-orcid":false,"given":"Michael Willian","family":"Favoreto","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Ponta Grossa,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8634-8088","authenticated-orcid":false,"given":"Rubia Elisa","family":"Lenz","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Ponta Grossa,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3867-0814","authenticated-orcid":false,"given":"Maria Eduarda","family":"Serra","sequence":"additional","affiliation":[{"name":"UniversidadeEstadual de Ponta Grossa,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7041-3084","authenticated-orcid":false,"given":"Christiane Philippini Ferreira","family":"Borges","sequence":"additional","affiliation":[{"name":"UniversidadeEstadual de Ponta Grossa,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9880-4856","authenticated-orcid":false,"given":"Alessandro D","family":"Loguercio","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Ponta Grossa,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6798-2094","authenticated-orcid":false,"given":"Alessandra","family":"Reis","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Ponta Grossa,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2020,6]]},"reference":[{"key":"ref1","series-title":"Bleaching and related agents. 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