{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T12:06:35Z","timestamp":1789128395168,"version":"build-2803163510"},"reference-count":24,"publisher":"FapUNIFESP (SciELO)","issue":"4","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. Dent. J."],"abstract":"<jats:p>Abstract Orthodontics patients usual develop demineralization and present cavity caries lesions after six months. Minimally invasive procedures have been the goal in modern dental practice. The aim of this study was to evaluate the effect of ClinproTMXT Varnish, on the enamel surface roughness and severity of white spot lesions. Twenty premolars were submitted to bond brackets and experimental induction of demineralization and randomly divided into 2 groups: GI - fluoride varnish (Colgate Duraphat\u00ae); GII - Ionomeric Sealant (ClinproTMXT Varnish). The treatment was applied around the brackets. The surface roughness of specimens was analyzed, before treatment and 12 weeks after treatment by laser confocal microscopy, and the severity of the white spot lesion was by laser fluorescence device. The data were analyzed by non-parametric Wilcoxon and Mann-Whitney Test, at 5% significance, roughness percentage reduction was performed. The severity of demineralization decreased in both, GI (p = 0.005) and GII (p = 0.019). Enamel superficial roughness levels decreased in GI and GII. As well as the roughness percentage, being more expressive in the ClinproTMXT Varnish group (85,09%). Colgate Duraphat\u00ae or Clinpro\u2122 XT Varnish reduced the severity of the demineralization and decreased the superficial roughness on the enamel. The Clinpro\u2122 XT Varnish was superior to superficial roughness on enamel.<\/jats:p>","DOI":"10.1590\/0103-6440202305405","type":"journal-article","created":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T11:16:33Z","timestamp":1698059793000},"page":"143-149","source":"Crossref","is-referenced-by-count":4,"title":["Efficacy of ClinproTMXT Varnish surrounding brackets on the enamel surface of white spot lesion."],"prefix":"10.1590","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3313-2152","authenticated-orcid":false,"given":"Ana Zilda Nazar","family":"Bergamo","sequence":"first","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5368-3947","authenticated-orcid":false,"given":"Lucas Portilho","family":"Miguel","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0885-0056","authenticated-orcid":false,"given":"Renata Zoraida Rizental","family":"Delgado","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3247-0248","authenticated-orcid":false,"given":"Regina Guenka","family":"Palma-Dibb","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0945-4028","authenticated-orcid":false,"given":"Juliana Jendiroba","family":"Faraoni","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9785-5766","authenticated-orcid":false,"given":"Patricia","family":"Gat\u00f3n-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"University of Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0230-1347","authenticated-orcid":false,"given":"Raquel Assed Bezerra da","family":"Silva","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7118-6859","authenticated-orcid":false,"given":"L\u00e9a Assed Bezerra da","family":"Silva","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8802-6480","authenticated-orcid":false,"given":"Paulo","family":"Nelson-Filho","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2023,8]]},"reference":[{"issue":"12","key":"ref1","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3390\/dj9120147","article-title":"Minimally Invasive Therapies for the Management of Dental Caries-A Literature Review","volume":"9","author":"Desai H","year":"2021","journal-title":"Dent J"},{"issue":"5","key":"ref2","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.pcl.2018.05.004","article-title":"Early Childhood Caries","volume":"65","author":"Seow WK","year":"2018","journal-title":"Pediatr. 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