{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T11:26:47Z","timestamp":1788953207812,"version":"build-2803163510"},"reference-count":33,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. Dent. J."],"abstract":"<jats:p>Abstract Dental implants have become the most effective treatment option for replacing missing teeth, worldwide. The popularity and demand for dental implants are continually increasing. Nevertheless, its complications are undeniable. Peri-implant diseases, including peri-implant mucositis and peri-implantitis, are a multifaceted clinical condition. Therefore, it is in the best interest to optimize the management of peri-implantitis, and there are still numerous methods to treat and manage infections in the vicinity of dental implants. The main goal of peri-implantitis treatment is to arrest disease progression, eliminate infection, and reconstruct damaged tissues around the implant. The clinical evidence on treating peri-implantitis that is available in PubMed was reviewed. Additionally, we presented the most comprehensive management strategies. As a result, numerous clinical trials recommended mechanical debridement and local administration of antimicrobial agents as well as topical oxygen therapy to mitigate bacterial biofilm and manage infection. The regenerative (bone grafting) approach for the treatment of peri-implantitis is another effective method. Finally, implant surface engineering can address high antibacterial efficacy and site-specific biofilm reduction.<\/jats:p>","DOI":"10.1590\/0103-6440202406160","type":"journal-article","created":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T10:43:36Z","timestamp":1729853016000},"source":"Crossref","is-referenced-by-count":5,"title":["Management of Infected Tissues Around Dental Implants: A Short Narrative Review"],"prefix":"10.1590","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8247-3367","authenticated-orcid":false,"given":"Hamdan","family":"Alghamdi","sequence":"first","affiliation":[{"name":"King Saud University,  Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0873-0767","authenticated-orcid":false,"given":"Minas","family":"Leventis","sequence":"additional","affiliation":[{"name":"Kapodistrian University of Athens,  Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4076-4905","authenticated-orcid":false,"given":"Tatiana","family":"Deliberador","sequence":"additional","affiliation":[{"name":"Latin American Institute of Dental Research and Education,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2024]]},"reference":[{"issue":"13","key":"ref1","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1177\/0022034518792567","article-title":"Trends in dental implant use in the US, 1999-2016, and projections to 2026","volume":"97","author":"Elani HW","year":"2018","journal-title":"Journal of dental research"},{"issue":"2","key":"ref2","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jhin.2009.02.010","article-title":"A review of dental implants and infection","volume":"72","author":"Pye AD","year":"2009","journal-title":"Journal of Hospital infection"},{"issue":"3","key":"ref3","first-page":"263","article-title":"Peri-implant diseases: Current understanding and management","volume":"14","author":"Barootchi S","year":"2021","journal-title":"Int J Oral Implantol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/j.1600-051X.2008.01275.x","article-title":"Peri\u2010implant diseases: diagnosis and risk indicators","volume":"35","author":"Heitz\u2010Mayfield LJ","year":"2008","journal-title":"Journal of clinical periodontology"},{"key":"ref5","first-page":"S237","article-title":"Peri\u2010implant mucositis","volume":"45","author":"Heitz\u2010Mayfield LJ","year":"2018","journal-title":"Journal of clinical periodontology"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"S246","DOI":"10.1111\/jcpe.12954","article-title":"Peri\u2010implantitis","volume":"45","author":"Schwarz F","year":"2018","journal-title":"Journal of clinical periodontology"},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.dental.2021.02.005","article-title":"Race to invade: Understanding soft tissue integration at the transmucosal region of titanium dental implants","volume":"37","author":"Guo T","year":"2021","journal-title":"Dental Materials"},{"issue":"7","key":"ref8","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/s41579-018-0019-y","article-title":"Implant infections: adhesion, biofilm formation and immune evasion","volume":"16","author":"Arciola CR","year":"2018","journal-title":"Nature reviews microbiology"},{"issue":"616","key":"ref9","article-title":"Biofilm on dental implants: a review of the literature","volume":"24","author":"H\u00e4mmerle CH","year":"2009","journal-title":"Int. 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