{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T22:56:53Z","timestamp":1785884213711,"version":"3.56.0"},"reference-count":28,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"crossref","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. Dent. J."],"abstract":"<jats:p>Abstract We aimed to evaluate the effect of varying the tube current and the Metal Artifact Reduction (MAR) tool on the detection of the missing second mesiobuccal (MB2) canal. Forty maxillary molars (20 with and 20 without MB2) were selected and confirmed by micro-CT. The teeth underwent endodontic preparation, with the canals filled using gutta-percha and a silver-palladium metal post. CBCT scans were acquired using the OP300 Maxio system (voxel size: 0.085 mm, FOV: 50 x 50 mm) at 4 mA, 6.3 mA, and 12.5 mA, with and without MAR activation. The areas under the receiver operating characteristic curves (AUCs), sensitivities, and specificities were calculated for five examiners and compared using two-way ANOVA (p &lt; 0.05). Intra- and interexaminer agreements were assessed using the weighted Kappa test. The AUC values ranged from 0.90 to 0.94, sensitivity from 0.75 to 0.78, and specificity from 0.89 to 0.95. Intra- and interexaminer indices ranged from moderate to substancial. Based on the tube current settings or MAR activation, there were no significant differences in the MB2 canal detection. Therefore, varying the tube current and MAR tool activation did not affect MB2 canal detection, with values close to 4 mA without MAR activation recommended in this scenario to reflect a better dose-benefit ratio.<\/jats:p>","DOI":"10.1590\/0103-644020256491","type":"journal-article","created":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T15:02:47Z","timestamp":1761318167000},"source":"Crossref","is-referenced-by-count":2,"title":["Role of tube current variation and metal artifact reduction tool in CBCT for detection of missing MB2 canal"],"prefix":"10.1590","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1856-793X","authenticated-orcid":false,"given":"Caio","family":"Alencar-Palha","sequence":"first","affiliation":[{"name":"University of Campinas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5278-540X","authenticated-orcid":false,"given":"Marcyele Natane da Silva","family":"Morais","sequence":"additional","affiliation":[{"name":"University of Campinas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9777-4197","authenticated-orcid":false,"given":"Fernanda Bulh\u00f5es","family":"Fagundes","sequence":"additional","affiliation":[{"name":"University of Campinas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1327-4724","authenticated-orcid":false,"given":"Lucas P. Lopes","family":"Rosado","sequence":"additional","affiliation":[{"name":"University Center of Esp\u00edrito Santo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1425-5966","authenticated-orcid":false,"given":"Deborah Queiroz","family":"Freitas","sequence":"additional","affiliation":[{"name":"University of Campinas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9178-707X","authenticated-orcid":false,"given":"Frederico Sampaio","family":"Neves","sequence":"additional","affiliation":[{"name":"Federal University of Bahia,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2025]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1007\/s00784-020-03554-4","article-title":"Missed canals in endodontically treated maxillary molars of a Brazilian subpopulation: prevalence and association with periapical lesion using cone-beam computed tomography","volume":"25","author":"Duarte Do Carmo W","year":"2021","journal-title":"Clin Oral Investig"},{"issue":"9","key":"ref2","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.joen.2006.04.014","article-title":"Root and Root Canal Morphology of the Human Permanent Maxillary First Molar: A Literature Review","volume":"32","author":"Cleghorn BM","year":"2006","journal-title":"J Endod"},{"issue":"113","key":"ref3","article-title":"Second mesiobuccal root canal in maxillary molars-A systematic review and meta-analysis of prevalence studies using cone beam computed tomography","volume":"1","author":"Martins JNR","year":"2020","journal-title":"Arch Oral Biol"},{"issue":"5","key":"ref4","first-page":"39","article-title":"Efficacy of digital radiography for detecting a second mesiobuccal canal adjacent to unfilled or filled canals","volume":"69","author":"Rosado L de PL","year":"2021","journal-title":"Academy of General Dentistry"},{"key":"ref5","article-title":"Artefacts in CBCT: A review","author":"Schulze R","year":"2011","journal-title":"Dentomaxillofacial Radiology"},{"issue":"6","key":"ref6","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.11607\/jomi.3524","article-title":"Influence of the Milliamperage Settings on Cone Beam Computed Tomography Imaging for Implant Planning","volume":"29","author":"Vasconcelos T","year":"2014","journal-title":"Int J Oral Maxillofac Implants"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1259\/dmfr\/80899839","article-title":"Metal artefact reduction with cone beam CT: An in vitro study","volume":"41","author":"Bechara B","year":"2012","journal-title":"Dentomaxillofacial Radiology"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1007\/s00784-018-2558-z","article-title":"Diagnosis of vertical root fracture in teeth close and distant to implant: an in vitro study to assess the influence of artifacts produced in cone beam computed tomography","volume":"23","author":"Freitas DQ","year":"2019","journal-title":"Clin Oral Investig"},{"issue":"4","key":"ref9","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1007\/s00784-020-03538-4","article-title":"Freitas DQ. Do the tube current and metal artifact reduction influence the diagnosis of vertical root fracture in a tooth positioned in the vicinity of a zirconium implant? A CBCT study","volume":"25","author":"Fontenele RC","year":"2021","journal-title":"Clin Oral Investig"},{"issue":"5","key":"ref10","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1259\/dmfr\/43691321","article-title":"Evaluation of a cone beam CT artefact reduction algorithm","volume":"41","author":"Bechara B","year":"2012","journal-title":"Dentomaxillofacial Radiology"},{"key":"ref11","first-page":"676","article-title":"ALADAIP, beyond ALARA and towards personalized optimization for paediatric cone-beam CT. 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