{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T02:56:22Z","timestamp":1774580182027,"version":"3.50.1"},"reference-count":33,"publisher":"FapUNIFESP (SciELO)","issue":"7","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz J Med Biol Res"],"DOI":"10.1590\/1414-431x20176783","type":"journal-article","created":{"date-parts":[[2018,5,28]],"date-time":"2018-05-28T14:22:09Z","timestamp":1527517329000},"source":"Crossref","is-referenced-by-count":37,"title":["Comparison of serum PCT and CRP levels in patients infected by different pathogenic microorganisms: a systematic review and meta-analysis"],"prefix":"10.1590","volume":"51","author":[{"given":"Jun-Hua","family":"Tang","sequence":"first","affiliation":[{"name":"The First People\u2019s Hospital of Fuyang Hangzhou,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Ping","family":"Gao","sequence":"additional","affiliation":[{"name":"Hangzhou Cancer Hospital,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng-Fei","family":"Zou","sequence":"additional","affiliation":[{"name":"Zhejiang University International Hospital,  China; Shulan (Hangzhou) Hospital,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2018]]},"reference":[{"issue":"(Suppl 2)","key":"ref1","first-page":"ii41","article-title":"Management of pleural infection in adults: British Thoracic Society Pleural Disease Guideline 2010","volume":"65","author":"Davies HE","year":"2010","journal-title":"Thorax"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1086\/322627","article-title":"Excessive antibiotic use for acute respiratory infections in the United States","volume":"33","author":"Gonzales R","year":"2001","journal-title":"Clin infect Dis"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1378\/chest.111.3.676","article-title":"Impact of BAL data on the therapy and outcome of ventilator-associated pneumonia","volume":"111","author":"Luna CM","year":"1997","journal-title":"Chest"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1164\/ajrccm.156.1.9607030","article-title":"The value of routine microbial investigation in ventilator-associated pneumonia","volume":"156","author":"Rello J","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1378\/chest.115.2.462","article-title":"Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients","volume":"115","author":"Kollef MH","year":"1999","journal-title":"Chest"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1136\/bmj.315.7104.350","article-title":"Reattendance and complications in a randomised trial of prescribing strategies for sore throat: the medicalising effect of prescribing antibiotics","volume":"315","author":"Little P","year":"1997","journal-title":"BMJ"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1001\/archfami.7.1.45","article-title":"The cost of antibiotics in treating upper respiratory tract infections in a medicaid population","volume":"7","author":"Mainous 3rd AG","year":"1998","journal-title":"Arch Fam Med"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1164\/rccm.200601-074OC","article-title":"The bacteriology of pleural infection by genetic and standard methods and its mortality significance","volume":"174","author":"Maskell NA","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1093\/qjmed\/89.4.285","article-title":"The clinical course and management of thoracic empyema","volume":"89","author":"Ferguson AD","year":"1996","journal-title":"QJM"},{"key":"ref10","first-page":"321","article-title":"Pleural infection: what we need to know but don't","volume":"18","author":"Tobin CL","year":"2012","journal-title":"Curr"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"e49894","DOI":"10.1371\/journal.pone.0049894","article-title":"Ability of procalcitonin to discriminate infection from non-infective inflammation using two pleural disease settings","volume":"7","author":"McCann FJ","year":"2012","journal-title":"PloS One"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1097\/00003246-200004000-00011","article-title":"Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit","volume":"28","author":"Muller B","year":"2000","journal-title":"Crit Care Med"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1183\/09031936.00197208","article-title":"Biomarkers of infection for the differential diagnosis of pleural effusions","volume":"34","author":"Porcel JM","year":"2009","journal-title":"Eur Respir J"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/j.clinbiochem.2013.03.018","article-title":"Procalcitonin as a diagnostic marker in differentiating parapneumonic effusion from tuberculous pleurisy or malignant effusion","volume":"46","author":"Lee SH","year":"2013","journal-title":"Clin Biochem"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1097\/00003246-199903000-00024","article-title":"Procalcitonin used as a marker of infection in the intensive care unit","volume":"27","author":"Ugarte H","year":"1999","journal-title":"Crit Care Med"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1097\/00006454-199708000-00003","article-title":"Clinical applications of C-reactive protein in pediatrics","volume":"16","author":"Jaye DL","year":"1997","journal-title":"Pediatr Infect Dis J"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"274","DOI":"10.3109\/07853890009011772","article-title":"Function of C-reactive protein","volume":"32","author":"Du Clos TW","year":"2000","journal-title":"Ann Med"},{"key":"ref18","first-page":"112","article-title":"Clinical value of combined detection of PCT and CRP in patients with pulmonary infection","volume":"36","author":"Chen YJ","year":"2016","journal-title":"Clin Med"},{"key":"ref19","first-page":"23","article-title":"The value of the C-reactive protein and procalcitonin detection in patients with pulmonary infection","volume":"22","author":"Du HS","year":"2015","journal-title":"Lab Immunoassay Clin Med"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"574","DOI":"10.4187\/respcare.02741","article-title":"C-reactive protein, procalcitonin, clinical pulmonary infection score, and pneumonia severity scores in nursing home acquired pneumonia","volume":"59","author":"Porfyridis I","year":"2014","journal-title":"Respir Care"},{"key":"ref21","first-page":"940","article-title":"Clinical difference and value of serum procalcitonin in peripheral blood of patients with different pathogens pulmonary infection","volume":"10","author":"Sun WF","year":"2011","journal-title":"Chin J Diffic Compl Cas"},{"key":"ref22","first-page":"2621","article-title":"Value of procalcitonin detection in diagnosis and treatment of severe pulmonary infection","volume":"37","author":"Wang XD","year":"2016","journal-title":"Int J Lab Med"},{"key":"ref23","first-page":"150","article-title":"Analysis and value evaluation of C reactive protein and procalcitonin in patients with pulmonary infection","volume":"22","author":"Xiao L","year":"2015","journal-title":"Cap Med"},{"key":"ref24","first-page":"2824","article-title":"Diagnostic value of serum procalcitonin detection in patients with pneumonia","volume":"23","author":"Yang AL","year":"2014","journal-title":"Modern J Integr Trad Chinese Western Med"},{"key":"ref25","first-page":"186","article-title":"Clinical significance of C reactive protein and calcitonin proto detection in patients with pulmonary infection","volume":"26","author":"Zhang JY","year":"2015","journal-title":"China Foreign Med Treat"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta4100","article-title":"Publication and related biases","volume":"4","author":"Song F","year":"2000","journal-title":"Health Technol Assess"},{"key":"ref27","first-page":"248","article-title":"Prevalence and influence of diagnostic tests for acute respiratory tract infections in primary care","volume":"136","author":"Briel M","year":"2006","journal-title":"Swiss Med Weekly"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1136\/bmj.324.7340.783","article-title":"Evidence base of clinical diagnosis: Rational, cost effective use of investigations in clinical practice","volume":"324","author":"Winkens R","year":"2002","journal-title":"BMJ"},{"key":"ref29","first-page":"118","article-title":"Early markers of infection and sepsis in newborns and children","volume":"5","author":"Carcillo JA","year":"2006","journal-title":"Adv Sepsis"},{"key":"ref30","first-page":"e854","article-title":"Procalcitonin measurement at 24 hours of age may be helpful in the prompt diagnosis of early-onset neonatal sepsis. International journal of infectious diseases","volume":"15","author":"Altunhan H","year":"2011","journal-title":"IJID"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1378\/chest.06-1500","article-title":"Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy","volume":"131","author":"Stolz D","year":"2007","journal-title":"Chest"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/S0140-6736(04)15591-8","article-title":"Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial","volume":"363","author":"Christ-Crain M","year":"2004","journal-title":"Lancet"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1086\/421997","article-title":"Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis","volume":"39","author":"Simon L","year":"2004","journal-title":"Clin Infect Dis"}],"container-title":["Brazilian Journal of Medical and Biological Research"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/bjmbr\/v51n7\/1414-431X-bjmbr-51-7-e6783.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T13:02:04Z","timestamp":1581426124000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0100-879X2018000700610&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":33,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2018]]}},"alternative-id":["S0100-879X2018000700610"],"URL":"https:\/\/doi.org\/10.1590\/1414-431x20176783","relation":{},"ISSN":["1414-431X","0100-879X"],"issn-type":[{"value":"1414-431X","type":"electronic"},{"value":"0100-879X","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]},"article-number":"e6783"}}