{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T09:51:22Z","timestamp":1778665882457,"version":"3.51.4"},"reference-count":21,"publisher":"FapUNIFESP (SciELO)","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz J Med Biol Res"],"DOI":"10.1590\/1414-431x20187952","type":"journal-article","created":{"date-parts":[[2018,11,24]],"date-time":"2018-11-24T18:11:18Z","timestamp":1543083078000},"source":"Crossref","is-referenced-by-count":17,"title":["NOP14 inhibits melanoma proliferation and metastasis by regulating Wnt\/\u03b2-catenin signaling pathway"],"prefix":"10.1590","volume":"52","author":[{"given":"Jingrong","family":"Li","sequence":"first","affiliation":[{"name":"Affiliated Hospital of Jinan University, China; Guangzhou First People's Hospital, School of Medicine, South China University of Technology, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruihua","family":"Fang","sequence":"additional","affiliation":[{"name":"Guangzhou First People's Hospital, School of Medicine, South China University of Technology, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianqin","family":"Wang","sequence":"additional","affiliation":[{"name":"Guangzhou Institute of Dermatology, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liehua","family":"Deng","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Jinan University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2019]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3322\/caac.21338","article-title":"Cancer statistics in China, 2015","volume":"66","author":"Chen W","year":"2016","journal-title":"CA Cancer J Clin"},{"key":"ref2","first-page":"18","article-title":"A global review of melanoma follow-up guidelines","volume":"6","author":"Trotter SC","year":"2013","journal-title":"J Clin Aesthet Dermatol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/ijc.27616","article-title":"International trends in the incidence of malignant melanoma 1953-2008--are recent generations at higher or lower risk?","volume":"132","author":"Erdmann F","year":"2013","journal-title":"Int J Cancer"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/cncr.22427","article-title":"Chemotherapy for metastatic melanoma: time for a change?","volume":"109","author":"Gogas HJ","year":"2007","journal-title":"Cancer"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.1056\/NEJMoa1103782","article-title":"Improved survival with vemurafenib in melanoma with BRAF V600E mutation","volume":"364","author":"Chapman PB","year":"2011","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1007\/s12325-014-0148-2","article-title":"Melanoma: diagnosis, staging, and treatment. Consensus group recommendations","volume":"31","author":"Berrocal A","year":"2014","journal-title":"Adv Ther"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"3644","DOI":"10.1091\/mbc.12.11.3644","article-title":"Novel stress-responsive genes EMG1 and NOP14 encode conserved, interacting proteins required for 40S ribosome biogenesis","volume":"12","author":"Liu PC","year":"2001","journal-title":"Mol Biol Cell"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1126\/science.1079447","article-title":"Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification","volume":"299","author":"Ruggero D","year":"2003","journal-title":"Science"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.canlet.2012.03.010","article-title":"NOP14 promotes proliferation and metastasis of pancreatic cancer cells","volume":"322","author":"Zhou B","year":"2012","journal-title":"Cancer Lett"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"25701","DOI":"10.18632\/oncotarget.4573","article-title":"NOP14 suppresses breast cancer progression by inhibiting NRIP1\/Wnt\/beta-catenin pathway","volume":"6","author":"Lei JJ","year":"2015","journal-title":"Oncotarget"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"7378","DOI":"10.1093\/nar\/gkt502","article-title":"DNA damage-induced inhibition of rRNA synthesis by DNA-PK and PARP-1","volume":"41","author":"Calkins AS","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"e8370","DOI":"10.1371\/journal.pone.0008370","article-title":"The Noc-domain containing C-terminus of Noc4p mediates both formation of the Noc4p-Nop14p submodule and its incorporation into the SSU processome","volume":"4","author":"Kuhn H","year":"2009","journal-title":"PLoS One"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"871","DOI":"10.4161\/cbt.20839","article-title":"Exome sequencing and digital PCR analyses reveal novel mutated genes related to the metastasis of pancreatic ductal adenocarcinoma","volume":"13","author":"Zhou B","year":"2012","journal-title":"Cancer Biol Ther"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1038\/ncomms4127","article-title":"The central role of EED in the orchestration of polycomb group complexes","volume":"5","author":"Cao Q","year":"2014","journal-title":"Nat Commun"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"rs6","DOI":"10.1126\/scisignal.2002255","article-title":"Charting the landscape of tandem BRCT domain-mediated protein interactions","volume":"5","author":"Woods NT","year":"2012","journal-title":"Sci Signal"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.molcel.2011.03.031","article-title":"Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation","volume":"42","author":"Merrick KA","year":"2011","journal-title":"Mol Cell"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"13941","DOI":"10.1007\/s13277-016-5271-z","article-title":"MicroRNA-15a inhibits the growth and invasiveness of malignant melanoma and directly targets on CDCA4 gene","volume":"37","author":"Alderman C","year":"2016","journal-title":"Tumour Biol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.cell.2012.05.012","article-title":"Wnt\/beta-catenin signaling and disease","volume":"149","author":"Clevers H","year":"2012","journal-title":"Cell"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7888\/juoeh.38.1","article-title":"Clinicopathological implications of Wingless\/int1 (WNT) signaling pathway in pancreatic ductal adenocarcinoma","volume":"38","author":"Nakamoto M","year":"2016","journal-title":"J Uoeh"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"5372","DOI":"10.1158\/1078-0432.CCR-13-2491","article-title":"Molecular pathways: epigenetic modulation of Wnt-glycogen synthase kinase-3 signaling to target human cancer stem cells","volume":"20","author":"Benoit YD","year":"2014","journal-title":"Clin Cancer Res"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1002\/jcb.24803","article-title":"Factors affecting the nuclear localization of beta-catenin in normal and malignant tissue","volume":"115","author":"Morgan RG","year":"2014","journal-title":"J Cell Biochem"}],"container-title":["Brazilian Journal of Medical and Biological Research"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/bjmbr\/v52n1\/1414-431X-bjmbr-52-1-e7952.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,15]],"date-time":"2020-11-15T23:28:30Z","timestamp":1605482910000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0100-879X2019000100604&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019]]}},"alternative-id":["S0100-879X2019000100604"],"URL":"https:\/\/doi.org\/10.1590\/1414-431x20187952","relation":{},"ISSN":["1414-431X","0100-879X"],"issn-type":[{"value":"1414-431X","type":"electronic"},{"value":"0100-879X","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]},"article-number":"e7952"}}