{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:17:48Z","timestamp":1787023068224,"version":"build-2736575974"},"reference-count":40,"publisher":"FapUNIFESP (SciELO)","issue":"3","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz J Med Biol Res"],"DOI":"10.1590\/1414-431x20199102","type":"journal-article","created":{"date-parts":[[2020,3,2]],"date-time":"2020-03-02T09:01:17Z","timestamp":1583139677000},"source":"Crossref","is-referenced-by-count":11,"title":["The APOB rs693 polymorphism impacts the lipid profile of Brazilian older adults"],"prefix":"10.1590","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8960-6356","authenticated-orcid":false,"given":"E.S.","family":"Alves","sequence":"first","affiliation":[{"name":"Universidade de Bras\u00edlia, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6247-1700","authenticated-orcid":false,"given":"A.D.","family":"Henriques","sequence":"additional","affiliation":[{"name":"Universidade de Bras\u00edlia, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2820-2101","authenticated-orcid":false,"given":"A.C.","family":"Tonet-Furioso","sequence":"additional","affiliation":[{"name":"Universidade de Bras\u00edlia, Brasil; Universidade Cat\u00f3lica de Bras\u00edlia, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4471-4665","authenticated-orcid":false,"given":"R.S.","family":"Paula","sequence":"additional","affiliation":[{"name":"Universidade de Bras\u00edlia, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6673-5507","authenticated-orcid":false,"given":"L.O.","family":"Gomes","sequence":"additional","affiliation":[{"name":"Universidade Cat\u00f3lica de Bras\u00edlia, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2605-1335","authenticated-orcid":false,"given":"C.F.","family":"Moraes","sequence":"additional","affiliation":[{"name":"Universidade de Bras\u00edlia, Brasil; Universidade Cat\u00f3lica de Bras\u00edlia, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1775-7176","authenticated-orcid":false,"given":"O.T.","family":"N\u00f3brega","sequence":"additional","affiliation":[{"name":"Universidade de Bras\u00edlia, Brasil; Universidade de Bras\u00edlia, Brasil; Institut Universitaire de G\u00e9riatrie de Montr\u00e9al, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2020]]},"reference":[{"key":"ref1","series-title":"Geneva: World Health Organization","year":"2015"},{"key":"ref2","series-title":"World health statistics 2018: monitoring health for the SDGs, Sustainable Development Goals","year":"2018"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1002\/ejlt.201000346","article-title":"ApoB (Xba I) polymorphism and lipid variation in Teharnian population","volume":"113","author":"Daheshpour MS","year":"2011","journal-title":"Eur J Lipid Sci Technol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"190","DOI":"10.2174\/1874613601610010190","article-title":"Apolipoprotein B gene polymorphisms and dyslipidemia in HIV infected adult Zimbabweans","volume":"10","author":"Kodogo V","year":"2016","journal-title":"Open AIDS J"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jgeb.2015.09.005","article-title":"Apolipoprotein B polymorphism distribution among a sample of obese Egyptian females with visceral obesity and its influence on lipid profile","volume":"13","author":"Hassan NE","year":"2015","journal-title":"J Genet Eng Biotechnol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s12944-018-0696-6","article-title":"Association between apolipoprotein B genetic polymorphism and the risk of calcific aortic stenosis in Chinese subjects, in Xinjiang, China","volume":"17","author":"Wang YT","year":"2018","journal-title":"Lipids Health Dis"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.atherosclerosis.2009.01.004","article-title":"Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review","volume":"206","author":"Benn M","year":"2009","journal-title":"Atherosclerosis"},{"key":"ref8","first-page":"999","article-title":"Genetic variation of apolipoproteins, diet and other environmental interactions; an updated review","volume":"28","author":"Sotos-Prieto M","year":"2013","journal-title":"Nutr Hosp"},{"key":"ref9","first-page":"1","article-title":"APOA1 and APOB polymorphisms and apolipoprotein concentrations as biomarkers of risk in acute coronary syndrome: Relationship with lipid-lowering therapy effectiveness","volume":"151","author":"Casillas-Mu\u00e3oz F","year":"2018","journal-title":"Med Clin"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1007\/s13258-015-0292-3","article-title":"Four Apolipoprotein B gene polymorphisms and the risk for coronary artery disease: a meta-analysis of 47 studies","volume":"37","author":"Xiao D","year":"2015","journal-title":"Genes Genom"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"26","DOI":"10.4103\/0971-6866.112880","article-title":"Association of apolipoprotein B XbaI gene polymorphism and lipid profile in northern Indian obese","volume":"19","author":"Srivastava N","year":"2013","journal-title":"Indian J Hum Genet"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.cca.2012.11.028","article-title":"Genetic variants in genes related to lipid metabolism and atherosclerosis, dyslipidemia and atorvastatin response","volume":"417","author":"Rodrigues AC","year":"2013","journal-title":"Clin Chim Acta"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1024\/0301-1526\/a000346","article-title":"Polymorphisms XbaI (rs693) and EcoRI (rs1042031) of the ApoB gene are associated with carotid plaques but not with carotid intima-media thickness in patients with diabetes mellitus type 2","volume":"43","author":"Nikolajevic Starcevic J","year":"2014","journal-title":"Vasa"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1186\/s12944-017-0558-7","article-title":"Associations of the APOB rs693 and rs17240441 polymorphisms with plasma APOB and lipid levels: a meta-analysis","volume":"16","author":"Niu C","year":"2017","journal-title":"Lipids Health Dis"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S1995-7645(13)60193-5","article-title":"Correlation between the Xba I polymorphism of apoB gene and serum lipid profiles in Li ethnic group","volume":"7","author":"Liu YL","year":"2014","journal-title":"Asian Pac J Trop Med"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s10528-011-9468-y","article-title":"Polymorphism of the apolipoprotein B gene and association with plasma lipid and lipoprotein levels in the Mongolian Buryat","volume":"50","author":"Tsunoda K","year":"2012","journal-title":"Biochem Genet"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.3748\/wjg.v16.i20.2549","article-title":"XbaI polymorphisms of apolipoprotein B gene: another risk factor of gallstone formation after radical gastrectomy","volume":"16","author":"Liu FL","year":"2010","journal-title":"World J Gastroenterol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s12952-015-0026-8","article-title":"No association of apolipoprotein B gene polymorphism and blood lipids in obese Egyptian subjects","volume":"14","author":"Bogari NM","year":"2015","journal-title":"J Negat Results Biomed"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1186\/cc1521","article-title":"Statistics review 4: Sample size calculations","volume":"6","author":"Whitley E","year":"2002","journal-title":"Crit Care"},{"key":"ref20","first-page":"1","article-title":"VI Brazilian Guidelines on Hypertension","volume":"95","year":"2010","journal-title":"Arq Bras de Cardiol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","article-title":"Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge","volume":"18","author":"Friedewald WT","year":"1972","journal-title":"Clin Chem"},{"key":"ref22","first-page":"189","article-title":"\u201cMini-mental state\u201d A practical method for grading the cognitive state of patients for the clinician.","volume":"12","author":"Folstein MF","year":"1975","journal-title":"J Psychiatr Res"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1590\/S0004-282X2008000400016","article-title":"Norms for the mini-mental state examination: adjustment of the cut-off point in population-based studies (evidences from the Bambu\u00ed Health Aging Study)","volume":"66","author":"Castro-Costa E","year":"2008","journal-title":"Arq Neuro-Psiquiatr"},{"key":"ref24","series-title":"Tabela de composi\u00e7\u00e3o de alimentos: suporte para decis\u00e3o nutricional. 2th. ed.","author":"Philippi ST","year":"2002"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s40520-015-0445-x","article-title":"Habitual dietary intake and mediators of the inflammaging process in Brazilian older women","volume":"28","author":"Paula RS","year":"2016","journal-title":"Aging Clin Exp Res"},{"key":"ref26","series-title":"Physical status: the use and interpretation of anthropometry","year":"1995"},{"key":"ref27","series-title":"J Am Diet Assoc","first-page":"691","volume":"93","year":"1993"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1037\/0033-2909.112.1.155","article-title":"A power primer","volume":"112","author":"Cohen J","year":"1992","journal-title":"Psychol Bull"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s11010-009-0313-0","article-title":"Dietary fat and apolipoprotein genotypes modulate plasma lipoprotein levels in Brazilian elderly women","volume":"337","author":"Paula RS","year":"2010","journal-title":"Mol Cell Biochem"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/s12944-015-0125-z","article-title":"Association between the APOB XbaI and EcoRI polymorphisms and lipids in Chinese: a meta-analysis","volume":"14","author":"Gu W","year":"2015","journal-title":"Lipids Health Dis"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"e011433","DOI":"10.1161\/JAHA.118.011433","article-title":"Trajectories of blood lipid concentrations over the adult life course and risk of cardiovascular disease and all-cause mortality: observations from the Framingham study over 35 years","volume":"8","author":"Duncan MS","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1093\/ije\/dyg106","article-title":"Cholesterol, coronary heart disease, and stroke in the Asia Pacific region","volume":"32","author":"Zhang X","year":"2003","journal-title":"Int J Epidemiol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1399-0004.1993.tb03861.x","article-title":"DNA polymorphisms of the apolipoprotein B gene are associated with obesity and serum lipids in healthy Indians in Singapore","volume":"44","author":"Saha N","year":"1993","journal-title":"Clin Genet"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1177\/1470320315615047","article-title":"Association between apolipoprotein B gene polymorphisms and the risk of coronary heart disease (CHD): an update meta-analysis","volume":"16","author":"Zhang JZ","year":"2015","journal-title":"J Renin Angiotensin Aldosterone Syst"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/1098-2825(2001)15:1<19::AID-JCLA4>3.0.CO;2-#","article-title":"Apo B gene haplotype is associated with lipid profile of higher risk for coronary heart disease in caucasian brazilian men","volume":"15","author":"Machado MO","year":"2001","journal-title":"J Clin Lab Anal"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1006\/bbrc.2001.4740","article-title":"Variation in the human apoB signal peptide modulates apoB17 translocation","volume":"283","author":"Benhizia F","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1016\/S0022-2275(20)31513-3","article-title":"Postnatal development of hepatocellular apolipoprotein B assembly and secretion in the rat","volume":"42","author":"Plonn\u00e9 D","year":"2001","journal-title":"J Lipid Res"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1194\/jlr.M300020-JLR200","article-title":"Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER","volume":"44(5)","author":"Liao W","year":"2003","journal-title":"J Lipid Res"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"411","DOI":"10.33549\/physiolres.931020","article-title":"Apolipoprotein B signal peptide polymorphism: distribution and influence on lipid parameters in Tunisian population","volume":"56","author":"Kallel A","year":"2007","journal-title":"Physiol Res"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1089\/gtmb.2015.0126","article-title":"Association between apolipoprotein b XbaI polymorphism and coronary heart disease in Han Chinese population: a meta-analysis","volume":"20","author":"Chen Y","year":"2016","journal-title":"Genet Test Mol Biomarkers"}],"container-title":["Brazilian Journal of Medical and Biological Research"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/bjmbr\/v53n3\/1414-431X-bjmbr-53-3-e9102.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:51:20Z","timestamp":1665967880000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0100-879X2020000300608&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":40,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020]]}},"alternative-id":["S0100-879X2020000300608"],"URL":"https:\/\/doi.org\/10.1590\/1414-431x20199102","relation":{},"ISSN":["1414-431X","0100-879X"],"issn-type":[{"value":"1414-431X","type":"electronic"},{"value":"0100-879X","type":"print"}],"subject":[],"published":{"date-parts":[[2020]]},"article-number":"e9102"}}