{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T20:48:18Z","timestamp":1780606098318,"version":"3.54.1"},"reference-count":31,"publisher":"FapUNIFESP (SciELO)","issue":"4","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sao Paulo Med. J."],"DOI":"10.1590\/1516-3180.2018.0458220719","type":"journal-article","created":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T19:59:55Z","timestamp":1572465595000},"page":"349-355","source":"Crossref","is-referenced-by-count":4,"title":["Procalcitonin levels among patients with fever secondary to intracerebral hemorrhage and severe infection. A cross-sectional study"],"prefix":"10.1590","volume":"137","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0863-8530","authenticated-orcid":false,"given":"S\u00fcmeyye Selim","family":"Kara","sequence":"first","affiliation":[{"name":"F\u0131rat \u00dcniversitesi T\u0131p Fak\u00fcltesi,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2560-3265","authenticated-orcid":false,"given":"Ayhan","family":"Akbulut","sequence":"additional","affiliation":[{"name":"F\u0131rat \u00dcniversitesi T\u0131p Fak\u00fcltesi,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9052-7986","authenticated-orcid":false,"given":"Ay\u015fe Sa\u011fmak","family":"Tartar","sequence":"additional","affiliation":[{"name":"F\u0131rat \u00dcniversitesi T\u0131p Fak\u00fcltesi,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0463-3422","authenticated-orcid":false,"given":"Hatice Handan","family":"Akbulut","sequence":"additional","affiliation":[{"name":"F\u0131rat \u00dcniversitesi T\u0131p Fak\u00fcltesi,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6515-011X","authenticated-orcid":false,"given":"Kutbeddin","family":"Demirda\u011f","sequence":"additional","affiliation":[{"name":"F\u0131rat \u00dcniversitesi T\u0131p Fak\u00fcltesi,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0072-8582","authenticated-orcid":false,"given":"Azize","family":"Be\u015fta\u015f","sequence":"additional","affiliation":[{"name":"F\u0131rat \u00dcniversitesi T\u0131p Fak\u00fcltesi,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2019,7]]},"reference":[{"issue":"21","key":"ref1","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1001\/jama.2009.1754","article-title":"International study of the prevalence and outcomes of infection in intensive care units","volume":"302","author":"Vincent J","year":"2009","journal-title":"JAMA"},{"key":"ref2","series-title":"Sepsis: Tan\u0131mlar. Sepsis ve Tedavisi. Enfeksiyon hastal\u0131klar\u0131 tedavi dizisi-7","first-page":"9","author":"Alp E","year":"2004"},{"issue":"7","key":"ref3","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1097\/00003246-200107001-00011","article-title":"The endothelium in sepsis: Source of and a target for inflammation","volume":"29","author":"Hack CE","year":"2001","journal-title":"Crit Care Med"},{"issue":"4","key":"ref4","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1097\/00003246-200004000-00011","article-title":"Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit","volume":"28","author":"M\u00fcller B","year":"2000","journal-title":"Crit Care Med"},{"issue":"6","key":"ref5","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1097\/01.CCM.0000217961.75225.E9","article-title":"Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock","volume":"34","author":"Kumar A","year":"2006","journal-title":"Crit Care Med"},{"issue":"11","key":"ref6","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1136\/jnnp.2006.112730","article-title":"Non-infectious fever in the neurological intensive care unit: incidence, causes and predictors","volume":"78","author":"Rabinstein AA","year":"2007","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"3","key":"ref7","first-page":"533","article-title":"Delayed posttraumatic brain hyperthermia worsens outcome after fluid percussion brain injury: a light and electron microscopic study in rats","volume":"38","author":"Dietrich WD","year":"1996","journal-title":"Neurosurgery"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/1471-2334-8-38","article-title":"Serum procalcitonin elevation in critically ill patients at the onset of bacteremia caused by either Gram negative or Gram positive bacteria","volume":"8","author":"Charles PE","year":"2008","journal-title":"BMC Infect Dis"},{"issue":"2","key":"ref9","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1159\/000222778","article-title":"Central hyperthermia in acute stroke","volume":"62","author":"Sung CY","year":"2009","journal-title":"Eur Neurol"},{"key":"ref10","series-title":"Fever","first-page":"165","volume-title":"Studies of fever associated with cerebral trauma and intracranial hemorrhage in experimental animals","author":"Rudy TA","year":"1980"},{"issue":"4","key":"ref11","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1097\/00003246-200004000-00007","article-title":"Relationship between procalcitonin plasma levels and severity of injury, sepsis, organ failure, and mortality in injured patients","volume":"28","author":"Wanner GA","year":"2000","journal-title":"Crit Care Med"},{"issue":"1","key":"ref12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0924-8579(02)00047-X","article-title":"Procalcitonin as a marker of sepsis","volume":"20","author":"Carrol ED","year":"2002","journal-title":"Int J Antimicrob Agents"},{"key":"ref13","series-title":"Procalcitonin (PCT): a new, innovative infection parameter. Biochemical and clinical aspects","author":"Meisner M","year":"2000","edition":"3"},{"issue":"1-2","key":"ref14","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0009-8981(02)00101-8","article-title":"Pathobiochemistry and clinical use of procalcitonin","volume":"323","author":"Meisner M","year":"2002","journal-title":"Clin Chim Acta"},{"issue":"2","key":"ref15","first-page":"s59","article-title":"Procalcitonin and infection","volume":"18","author":"Ertu\u011frul \u00d6","year":"2005","journal-title":"Klimik Journal"},{"issue":"8","key":"ref16","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1097\/CCM.0000000000000330","article-title":"Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: results from a guideline-based performance improvement program","volume":"42","author":"Ferrer R","year":"2014","journal-title":"Crit Care Med"},{"issue":"5","key":"ref17","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/01.ccx.0000176694.92883.ce","article-title":"Biomarkers of sepsis: clinically useful?","volume":"11","author":"Meisner M","year":"2005","journal-title":"Curr Opin Care"},{"issue":"2","key":"ref18","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1023\/A:1007166521791","article-title":"Plasma levels of procalcitonin and interleukin-6 in acute myocardial infarction","volume":"25","author":"Buratti T","year":"2001","journal-title":"Inflammation"},{"issue":"3","key":"ref19","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/s12028-014-9960-4","article-title":"The utility of serum procalcitonin in distinguishing systemic inflammatory response syndrome from infection after aneurysmal subarachnoid hemorrhage","volume":"20","author":"Festic E","year":"2014","journal-title":"Neurocrit Care"},{"issue":"2","key":"ref20","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s12028-016-0337-8","article-title":"Procalcitonin is a Poor Predictor of Non-Infectious Fever in the Neurocritical Care Unit","volume":"27","author":"Halvorson K","year":"2017","journal-title":"Neurocrit Care"},{"issue":"4","key":"ref21","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1177\/0310057X0403200402","article-title":"Serum procalcitonin and C-reactive protein as markers of sepsis and outcome in patients with neurotrauma and subarachnoid haemorrhage","volume":"32","author":"O\u2019Connor E","year":"2004","journal-title":"Anaesth Intensive Care"},{"issue":"8","key":"ref22","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1212\/01.wnl.0000343046.88848.76","article-title":"Procalcitonin might help indiscrimination between meningeal neuro-Behcet disease and bacterial meningitis","volume":"72","author":"Suzuki N","year":"2009","journal-title":"Neurology"},{"issue":"2","key":"ref23","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1651-2227.1997.tb08870.x","article-title":"Procalcitonin and C-reactive protein levels in neonatal infections","volume":"86","author":"Monneret G","year":"1997","journal-title":"Acta Paediatr"},{"issue":"7","key":"ref24","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1111\/j.1469-0691.2004.00883.x","article-title":"Potential use of procalcitonin as a diagnostic criterion in febrile neutropenia: experience from a multicentre study","volume":"10","author":"Giamarellou H","year":"2004","journal-title":"Clin Microbiol Infect"},{"issue":"4","key":"ref25","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1186\/cc2877","article-title":"Procalcitonin and C-reactive protein during systemic inflammatory response syndrome, sepsis and organ dysfunction","volume":"8","author":"Castelli GP","year":"2004","journal-title":"Crit Care"},{"issue":"1","key":"ref26","doi-asserted-by":"crossref","first-page":"R12","DOI":"10.1186\/cc2396","article-title":"Procalcitonin as a marker of bacterial infection in the emergency department: an observational study","volume":"8","author":"Chan YL","year":"2004","journal-title":"Crit Care"},{"issue":"6","key":"ref27","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1177\/0310057X0303100603","article-title":"Procalcitonin: a marker of bacteraemia in SIRS","volume":"31","author":"Bell K","year":"2003","journal-title":"Anaesth Intensive Care"},{"issue":"6","key":"ref28","first-page":"643","article-title":"Diagnostic value of procalcitonin serum levels in comparison with C-reactive protein in allogeneic stem cell transplantation","volume":"87","author":"Hambach L","year":"2002","journal-title":"Haematologica"},{"issue":"3","key":"ref29","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/CPM.0b013e3180555bbe","article-title":"C-reactive protein and procalcitonin as markers of infection, inflammatory response, and sepsis","volume":"14","author":"Sierra R","year":"2007","journal-title":"Clinical Pulmonary Medicine"},{"issue":"1-2","key":"ref30","first-page":"69","article-title":"Procalcitonin, C-reactive protein, white blood cells and SOFA score in ICU: diagnosis and monitoring of sepsis","volume":"72","author":"Castelli GP","year":"2006","journal-title":"Minerva Anestesiol"},{"issue":"3","key":"ref31","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1097\/00003246-199903000-00024","article-title":"Procalcitonin used as a marker of infection in the intensive care unit","volume":"27","author":"Ugarte H","year":"1999","journal-title":"Crit Care Med"}],"container-title":["Sao Paulo Medical Journal"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/spmj\/v137n4\/1806-9460-spmj-137-04-349.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T03:03:54Z","timestamp":1611371034000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1516-31802019000400349&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":31,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2019,7]]}},"alternative-id":["S1516-31802019000400349"],"URL":"https:\/\/doi.org\/10.1590\/1516-3180.2018.0458220719","relation":{},"ISSN":["1806-9460","1516-3180"],"issn-type":[{"value":"1806-9460","type":"electronic"},{"value":"1516-3180","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]}}}