{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T09:25:27Z","timestamp":1781083527941,"version":"3.54.1"},"reference-count":27,"publisher":"FapUNIFESP (SciELO)","issue":"0","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Latino-Am. Enfermagem"],"abstract":"<jats:p>ABSTRACT Objective: to evaluate the effects of trolamine in the prevention or treatment of radiation dermatitis. Method: systematic review and meta-analysis. Detailed individual search strategies for Cinahl, Cochrane Library Central, LILACS, PubMed, and Web of Science were developed in January 2016. A manual search was also performed to find additional references. A grey literature search was executed by using Google Scholar. Two researchers independently read the titles and abstracts from every cross-reference. The risk of bias of the included studies was analyzed by the Cochrane Collaboration Risk of Bias Tool. The quality of evidence and grading of strength of recommendations was assessed using Grades of Recommendation, Assessment, Development and Evaluation (GRADE). Results: seven controlled clinical trials were identified. The controls used were calendula, placebo, institutional preference \/ usual care, Aquaphor\u00ae, RadiaCare\u2122, and Lipiderm\u2122. The studies were pooled using frequency of events and risk ratio with 95% confidence intervals, in subgroups according to radiation dermatitis graduation. Conclusion: based on the studies included in this review, trolamine cannot be considered as a standardized product to prevent or treat radiation dermatitis in patients with breast and head and neck cancer.<\/jats:p>","DOI":"10.1590\/1518-8345.2035.2929","type":"journal-article","created":{"date-parts":[[2018,5,5]],"date-time":"2018-05-05T19:19:31Z","timestamp":1525547971000},"source":"Crossref","is-referenced-by-count":23,"title":["Use of trolamine to prevent and treat acute radiation dermatitis: a systematic review and meta-analysis"],"prefix":"10.1590","volume":"26","author":[{"given":"Amanda Gomes de","family":"Men\u00eases","sequence":"first","affiliation":[{"name":"Universidade de Bras\u00edlia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula Elaine Diniz dos","family":"Reis","sequence":"additional","affiliation":[{"name":"Universidade de Bras\u00edlia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliete Neves Silva","family":"Guerra","sequence":"additional","affiliation":[{"name":"Universidade de Bras\u00edlia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graziela De Luca","family":"Canto","sequence":"additional","affiliation":[{"name":"Universidade Federal de Santa Catarina, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine Barros","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Universidade de Bras\u00edlia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2018,5,7]]},"reference":[{"issue":"7","key":"ref1","first-page":"11000","article-title":"Topical use of olive oil preparation to prevent radiodermatitis: results of a prospective study in nasopharyngeal carcinoma patients","volume":"8","author":"Cui Z","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1159\/000353974","article-title":"Prophylaxis of Acute Radiation Dermatitis with an Innovative FDA-Approved Two-Step Skin Care System in a Patient with Head and Neck Cancer Undergoing a Platin-Based Radiochemotherapy: A Case Report and Review of the Literature","volume":"227","author":"H\u00e4fner MF","year":"2013","journal-title":"Dermatology"},{"issue":"6","key":"ref3","first-page":"327","article-title":"Efectiveness of topical therapies in patients with breast cancer that experience radiodermatitis. 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