{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T22:52:10Z","timestamp":1772232730838,"version":"3.50.1"},"reference-count":33,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Latino-Am. Enfermagem"],"abstract":"<jats:p>Resumo  Objetivo:  analisar os fatores associados ao insucesso do Transplante de C\u00e9lulas-Tronco Hematopoi\u00e9ticas (TCTH) em pacientes submetidos ao retransplante de C\u00e9lulas-Tronco Hematopoi\u00e9ticas (RCTH).  M\u00e9todo:  estudo quantitativo do tipo caso-controle para avaliar pacientes submetidos ao RCTH. Para tanto, utilizou-se amostra pareada de dois controles para cada caso (2:1). O grupo caso foi constitu\u00eddo pelos prontu\u00e1rios de sa\u00fade com todos os pacientes que foram submetidos ao RCTH (28) e o grupo controle (56) incluiu pacientes que receberam apenas um transplante. Tr\u00eas vari\u00e1veis nortearam o pareamento: sexo, diagn\u00f3stico e tipo de transplante.  Resultados: vinte e quatro (85,71%) pacientes do grupo caso receberam retransplante devido a recidiva da doen\u00e7a e quatro (14.29%) devido a falha do enxerto. Uma diferen\u00e7a estat\u00edstica foi encontrada na an\u00e1lise entre os pacientes que n\u00e3o usaram o \u00e1cido ursodesoxic\u00f3lico, analg\u00e9sicos opioides ou imunossupressores. A necessidade de um RCTH entre aqueles que usaram estes medicamentos de forma inapropriada foi 16,12, 12,79 e 4,5 vezes maior, respectivamente, do que entre os que as usaram corretamente.  Conclus\u00e3o:  houve uma diferen\u00e7a relacionada ao motivo que levou ao retransplante e os indiv\u00edduos analisados. A conclus\u00e3o \u00e9 que a raz\u00e3o preditiva para retransplante nesta amostra foi a recidiva da doen\u00e7a.<\/jats:p>","DOI":"10.1590\/1518-8345.5794.3569","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T15:44:09Z","timestamp":1652715849000},"source":"Crossref","is-referenced-by-count":1,"title":["An\u00e1lise dos fatores associados ao retransplante de c\u00e9lulas-tronco hematopoi\u00e9ticas: estudo caso-controle"],"prefix":"10.1590","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5322-7987","authenticated-orcid":false,"given":"Isabelle Campos de","family":"Azevedo","sequence":"first","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brazil; Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior (CAPES),  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9123-232X","authenticated-orcid":false,"given":"Marcos Antonio","family":"Ferreira J\u00fanior","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7492-2735","authenticated-orcid":false,"given":"An\u00e1lia Andr\u00e9ia de Ara\u00fajo","family":"Nascimento","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4672-2303","authenticated-orcid":false,"given":"Allyne Fortes","family":"Vitor","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6835-0574","authenticated-orcid":false,"given":"Elen Ferraz","family":"Teston","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3586-1313","authenticated-orcid":false,"given":"Oleci Pereira","family":"Frota","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8140-8320","authenticated-orcid":false,"given":"Viviane Euz\u00e9bia Pereira","family":"Santos","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Norte,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2022]]},"reference":[{"issue":"4","key":"ref1","first-page":"104","article-title":"Hematopoietic stem cell transplantation for Inborn Errors of Immunity","volume":"2","author":"Fernandes JF","year":"2021","journal-title":"JBMTCT"},{"issue":"3","key":"ref2","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.transproceed.2018.02.015","article-title":"Epidemiologic Profile of Patients Transplanted with Hematopoietic Stem Cells in a Reference Service in the State of Rio Grande do Norte, Brazil","volume":"50","author":"Azevedo IC","year":"2018","journal-title":"Transplant Proc"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.htct.2019.01.010","article-title":"Haploidentical transplantation outcomes are comparable with those obtained with identical human leukocyte antigen allogeneic transplantation in Chilean patients with benign and malignant hemopathies","volume":"42","author":"Sarmiento M","year":"2020","journal-title":"Hematol Transfus Cell Ther"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"319","DOI":"10.3389\/fimmu.2019.00309","article-title":"Achievement of tolerance induction to prevent acute graft-vs.-host disease","volume":"10","author":"Thangavelu G","year":"2019","journal-title":"Front Immunol"},{"issue":"2","key":"ref5","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1001\/jama.2018.18743","article-title":"Effect of Nonmyeloablative Hematopoietic Stem Cell Transplantation vs Continued Disease-Modifying Therapy on Disease Progression in Patients With Relapsing-Remitting Multiple Sclerosis: A Randomized Clinical Trial","volume":"321","author":"Burt RK","year":"2019","journal-title":"JAMA"},{"issue":"10","key":"ref6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0204914","article-title":"Early and late complications following hematopoietic stem cell transplantation in pediatric patients - 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