{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T11:15:32Z","timestamp":1780398932542,"version":"3.54.1"},"reference-count":59,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. J. Biol."],"abstract":"<jats:p>Abstract The work aims were to describe the histological and histochemical structure of the gastroesophageal tube of Iguana iguana and verify the occurrence and distribution of immunoreactive serotonin (5-HT) and somatostatin (SS) cells. Fragments of the gastrointestinal tract (GIT) of five iguanas were which underwent standard histological and immunohistochemistry technique. Immunoreactive cells for 5-HT and SS were quantified using the STEPanizer. The oesophagus has ciliated columnar pseudostratified epithelium with staining Alcian blue (AB) + and goblet cells highly reactive to periodic acid Schiff (PAS). In the cervical oesophagus, the numerical density of 5-HT cells per unit area (QA [5-HT cells]\/\u00b5m2) was 4.6x10-2 \u00b1 2.0 and celomatic oesophagus presented QA = 4.0x10-2 \u00b1 1.0. The epithelium of the stomach is simple columnar, PAS and AB +. The cranial and middle regions of the stomach presented (QA [5-HT cells]\/\u00b5m2) = 6.18x10-2 \u00b1 3.2 and the caudal region, QA = 0.6x10-2 \u00b1 0.2. The SS cells were only observed in the caudal stomach, with numerical density (QA [SS cells]\/\u00b5m2) = 1.4x10-2 \u00b1 0.9 In I. iguana, variation was observed in terms of the distribution of mucus secretions and the pattern of occurrence of serotonin and somatostatin-secreting enteroendocrine cells in the TGI, which possibly will result in an interspecific adaptive response.<\/jats:p>","DOI":"10.1590\/1519-6984.242086","type":"journal-article","created":{"date-parts":[[2021,6,21]],"date-time":"2021-06-21T12:14:20Z","timestamp":1624277660000},"source":"Crossref","is-referenced-by-count":4,"title":["Gastroesophageal tube of the Iguana iguana (Iguanidae): histological description, histochemical and immunohistochemical analysis of 5-HT and SS cells"],"prefix":"10.1590","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6827-7183","authenticated-orcid":false,"given":"A. O.","family":"Serra-Campos","sequence":"first","affiliation":[{"name":"Universidade Federal Fluminense, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5066-8020","authenticated-orcid":false,"given":"A. N. G.","family":"Abreu-Junior","sequence":"additional","affiliation":[{"name":"Universidade Federal do Piau\u00ed, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0970-7649","authenticated-orcid":false,"given":"A. A.","family":"Nascimento","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural do Rio de Janeiro, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2251-171X","authenticated-orcid":false,"given":"M.","family":"Abidu-Figueiredo","sequence":"additional","affiliation":[{"name":"Universidade Federal Rural do Rio de Janeiro, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9254-7462","authenticated-orcid":false,"given":"M. S. C. 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