{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:14:07Z","timestamp":1790644447248,"version":"4.1.0"},"reference-count":51,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. J. Biol."],"abstract":"<jats:p>Abstract The species Eugenia involucrata DC. is a plant native to Brazil and is traditionally used for intestinal problems, however, little research has documented about its biological potential and phytochemical profile. Thus, the objective of this study was to carry out preliminary phytochemical prospecting, antimicrobial and antioxidant potential of E. involucrata extracts. Using the E. involucrata leaves, aqueous and organic extracts were obtained using the following solvents (ethanol, methanol, hexane, acetone, dichloromethane and ethyl acetate). The phytochemical prospecting detected the presence of saponins, steroids, flavonoids and tannins in the extracts. Ethanolic and methanolic extracts presented antimicrobial activity for most of the bacterial strains tested, as well as for yeast Candida albicans, with concentrations between 3.12 and 50 mg\/mL. The ethanolic and metanolic extract presented high free radical sequestration potential (&gt;90%). The methanol extract showed an IC50 value statistically equal to that found for the commercial antioxidant BHT (p &lt;0.05). The crude extracts obtained with ethanol and methanol were the most promising. These results suggest that methanolic, ethanolic and aqueous extracts are a promising source of natural bioactive.<\/jats:p>","DOI":"10.1590\/1519-6984.245753","type":"journal-article","created":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T00:41:34Z","timestamp":1624927294000},"source":"Crossref","is-referenced-by-count":18,"title":["Antimicrobial, antioxidant activity and phytochemical prospection of Eugenia involucrata DC. leaf extracts"],"prefix":"10.1590","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0199-8330","authenticated-orcid":false,"given":"A. G.","family":"Toledo","sequence":"first","affiliation":[{"name":"Universidade Estadual do Oeste do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5877-8817","authenticated-orcid":false,"given":"J. G. de L. de","family":"Souza","sequence":"additional","affiliation":[{"name":"Universidade Estadual do Oeste do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8850-9124","authenticated-orcid":false,"given":"C. B.","family":"Santana","sequence":"additional","affiliation":[{"name":"Universidade Estadual do Oeste do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7568-8637","authenticated-orcid":false,"given":"A. P.","family":"Mallmann","sequence":"additional","affiliation":[{"name":"Universidade Estadual do Oeste do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5693-9637","authenticated-orcid":false,"given":"C. V.","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Universidade Estadual do Oeste do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4526-0060","authenticated-orcid":false,"given":"J. M.","family":"Corr\u00eaa","sequence":"additional","affiliation":[{"name":"Universidade Estadual do Oeste do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0486-8486","authenticated-orcid":false,"given":"F. G. da S.","family":"Pinto","sequence":"additional","affiliation":[{"name":"Universidade Estadual do Oeste do Paran\u00e1,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2023]]},"reference":[{"issue":"6","key":"ref1","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1111\/j.1745-4549.2011.00622.x","article-title":"Antioxidant and antibacterial activities of various extracts of Borago officinalis flowers","volume":"36","author":"ALIAKBARLU J.","year":"2012","journal-title":"Journal of Food Processing and Preservation"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.indcrop.2009.01.009","article-title":"Bioactive extracts from Cistus ladanifer and Arbutus unedo L","volume":"30","author":"ANDRADE D.","year":"2009","journal-title":"Industrial Crops and Products"},{"key":"ref3","first-page":"1","article-title":"Antimicrobial activity and phytochemical screening of branches, fruits and leaves of Eugenia brejoensis.","volume":"8","author":"AZEVEDO P.R.","year":"2012","journal-title":"Scientia Plena"},{"issue":"1","key":"ref4","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1080\/13880200802411771","article-title":"Antibacterial, cytotoxic and phytochemical screening of some traditional medicinal plants in Brazil","volume":"47","author":"BOUZADA M.L.M.","year":"2009","journal-title":"Pharmaceutical Biology"},{"issue":"19","key":"ref5","doi-asserted-by":"crossref","first-page":"7879","DOI":"10.1021\/jf0715323","article-title":"Antimicrobial and Antioxidant properties of Rosemary and Sage (Rosmarinus officinalis L. and Salvia officinalis L., Lamiaceae) essential oils","volume":"55","author":"BOZIN B.","year":"2007","journal-title":"Journal of Agricultural and Food Chemistry"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.indcrop.2013.04.003","article-title":"Effect of different extraction methodologies on the recovery of bioactive metabolites from Satureja parvifolia (Phil.) 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