{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:04:15Z","timestamp":1753887855813,"version":"3.41.2"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. J. Biol."],"abstract":"<jats:p>Abstract Linum usitatissimum L is a widely used traditionally for multiple ailments. The present research was carried out to explore the antimicrobial, and anti-biofilm activity of crude extract of Linum usitatissimum L (Lu. Cr). Phytochemical and proximate analyses were performed. The bandages of diabetic foot patients were collected from the various hospitals. The bandages were cultured to isolate the bacterial strains present on it. The disc diffusion method was used to identify the antimicrobial potential whereas the minimum inhibitory concentration of the Lu.Cr were also determined. Proximate analysis confirms moisture content 8.33%, ash content 4.33%, crude protein 21.20%, crude fat 49.2% and crude fiber 5.63%. It was revealed that Gram-positive bacteria are most prevalent among all study groups. Lu.Cr possess significant bactericidal potential against S. aureus among all other microbes. Owing to this potential, linseed coated bandages can be used alternatively for the treatment of diabetic foot.<\/jats:p>","DOI":"10.1590\/1519-6984.245807","type":"journal-article","created":{"date-parts":[[2021,8,6]],"date-time":"2021-08-06T12:08:33Z","timestamp":1628251713000},"source":"Crossref","is-referenced-by-count":4,"title":["Evaluation of methanolic crude extract of Linum usitatissimum for the removal of biofilm in diabetic foot isolates"],"prefix":"10.1590","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7898-1011","authenticated-orcid":false,"given":"M.","family":"Haroon","sequence":"first","affiliation":[{"name":"COMSATS University Islamabad, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7091-5682","authenticated-orcid":false,"given":"M. J.","family":"Iqbal","sequence":"additional","affiliation":[{"name":"COMSATS University Islamabad, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0197-1736","authenticated-orcid":false,"given":"W.","family":"Hassan","sequence":"additional","affiliation":[{"name":"COMSATS University Islamabad, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3171-1895","authenticated-orcid":false,"given":"S.","family":"Ali","sequence":"additional","affiliation":[{"name":"Sargodha Medical College, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5433-9155","authenticated-orcid":false,"given":"H.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Sialkot Medical College, Pakistan; Imran Idrees College of Pharmacy, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7544-3119","authenticated-orcid":false,"given":"S. U.","family":"Hassan","sequence":"additional","affiliation":[{"name":"Imran Idrees College of Pharmacy, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2023]]},"reference":[{"issue":"11","key":"ref1","first-page":"1","article-title":"The antibacterial effect of flaxseed extract on selective oral pathogens: comparative in vitro study","volume":"7","author":"ALAHMAD B.E.M.","year":"2018","journal-title":"World Journal of Pharmacy and Pharmaceutical Sciences"},{"issue":"2B","key":"ref2","first-page":"1086","article-title":"Antibacterial and antibiofilm activity of flaxseed oil","volume":"57","author":"AL-MATHKHURY H.J.F.","year":"2016","journal-title":"Iraqi Journal of Science"},{"issue":"4","key":"ref3","first-page":"465","article-title":"A comparative study on proximate composition, phytochemical screening, antioxidant and antimicrobial activities of Linum usitatisimum L. 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