{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:36:11Z","timestamp":1785425771975,"version":"3.56.0"},"reference-count":89,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. J. Biol."],"abstract":"<jats:p>Abstract The goal of this study is to review the overall prevalence, burden, and distribution of the dengue disease in Pakistan from 2000 to 2019. Literature was searched using different search engines like Google scholar, PubMed, etc. providing the keywords \u201cDengue disease\/infection, Dengue virus, DENV, DF\/DHF\/ DSS Pakistan\u201d. All the published research papers\/reports on the dengue virus over the period 2000 to 2019 were studied and selected data were summarized using MS Excel for windows such as total cases, age wise, gender, DENV serotype distribution, total DHF, and DSS patients. The literature providing insufficient data was excluded. The total number of cases reported during 2000-19 were 201,269. The maximum number of cases during the mentioned literature survey period was reported in Khyber Pakhtunkhwa (KP) (23.3%) followed by Punjab (3.8%) and Sindh (1.9%). The majority of dengue-infected cases were reported as Dengue fever (74.4%) followed by DHF (24.1%) and DSS (1.5%). Overall the deaths during the mentioned literature survey were 1082, of which the maximum mortalities were reported from KP (N=248) followed by Punjab (N=220). DENV remains a major public health problem in Pakistan and seems to remain endemic for a long time. The total prevalence of dengue infection is increased accordingly with time from 2000 to 2019. Moreover, all the four serotypes exist in Pakistan with increased mortalities.<\/jats:p>","DOI":"10.1590\/1519-6984.267982","type":"journal-article","created":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T15:27:49Z","timestamp":1681486069000},"source":"Crossref","is-referenced-by-count":10,"title":["Burden and distribution of dengue infection in Pakistan (2000-19): a review"],"prefix":"10.1590","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0773-5419","authenticated-orcid":false,"given":"A.","family":"Khattak","sequence":"first","affiliation":[{"name":"University of Peshawar, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7034-2570","authenticated-orcid":false,"given":"S.","family":"Khan","sequence":"additional","affiliation":[{"name":"University of Peshawar, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2163-8874","authenticated-orcid":false,"given":"I.","family":"Ali","sequence":"additional","affiliation":[{"name":"Gulf University for Science and Technology, Kuwait; COMSATS University, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5045-3098","authenticated-orcid":false,"given":"A.","family":"Gul","sequence":"additional","affiliation":[{"name":"University of Peshawar, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4740-4961","authenticated-orcid":false,"given":"M. N.","family":"Khabir","sequence":"additional","affiliation":[{"name":"University of Peshawar, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7383-6728","authenticated-orcid":false,"given":"B.","family":"Javed","sequence":"additional","affiliation":[{"name":"University of Peshawar, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6788-7361","authenticated-orcid":false,"family":"Ayesha","sequence":"additional","affiliation":[{"name":"University of Peshawar, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0691-9005","authenticated-orcid":false,"given":"M.","family":"Adnan","sequence":"additional","affiliation":[{"name":"University of Peshawar, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7137-9044","authenticated-orcid":false,"given":"S. N.","family":"Khan","sequence":"additional","affiliation":[{"name":"Kohat University of Science and Technology, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5463-535X","authenticated-orcid":false,"given":"S.","family":"Attaullah","sequence":"additional","affiliation":[{"name":"Islamia College Peshawar, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2024]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.transci.2013.07.034","article-title":"Frequency of dengue virus infection in blood donors in Sistan and Baluchestan province in Iran","volume":"50","author":"AGHAIE A.","year":"2014","journal-title":"Transfusion and Apheresis Science"},{"issue":"4II","key":"ref2","doi-asserted-by":"crossref","first-page":"997","DOI":"10.30541\/v46i4IIpp.997-1009","article-title":"Water resources and conservation strategy of Pakistan","volume":"46","author":"AHMED A.","year":"2007","journal-title":"Pakistan Development Review"},{"issue":"4","key":"ref3","first-page":"928","article-title":"Dengue virus serotypes and epidemiological features of dengue fever in Faisalabad, Pakistan","volume":"34","author":"AHMED I.","year":"2017","journal-title":"Tropical Biomedicine"},{"issue":"1","key":"ref4","first-page":"4","article-title":"Dengue fever outbreak in Karachi 2006--a study of profile and outcome of children under 15 years of age","volume":"58","author":"AHMED S.","year":"2008","journal-title":"The Journal of the Pakistan Medical Association"},{"issue":"7","key":"ref5","first-page":"463","article-title":"The 2011 dengue haemorrhagic fever outbreak in Lahore-an account of clinical parameters and pattern of haemorrhagic complications","volume":"23","author":"AHMED S.","year":"2013","journal-title":"Journal of the College of Physicians and Surgeons"},{"issue":"2","key":"ref6","first-page":"56","article-title":"Dengue fever in northern Pakistan: the hepatic implications","volume":"13","author":"AHMED S.I.","year":"2009","journal-title":"Journal of Rawalpindi Medical College"},{"key":"ref7","first-page":"3842","article-title":"Dengue outbreak in Khyber Pakhtoonkhwa, Pakistan 2013","volume":"1","author":"AKHTAR N.","year":"2014","journal-title":"European Academic Research"},{"issue":"1","key":"ref8","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1186\/s12985-016-0603-6","article-title":"Circulating serotypes of dengue virus and their incursion into non-endemic areas of Pakistan; a serious threat","volume":"13","author":"ALI A.","year":"2016","journal-title":"Virology Journal"},{"issue":"7","key":"ref9","doi-asserted-by":"crossref","first-page":"e518","DOI":"10.1016\/j.ijid.2013.01.007","article-title":"Seroepidemiology of dengue fever in Khyber Pakhtunkhawa, Pakistan","volume":"17","author":"ALI A.","year":"2013","journal-title":"International Journal of Infectious Diseases"},{"issue":"3","key":"ref10","first-page":"1","article-title":"Clinical profile and management of dengue fever at a tertiary care hospital in Pakistan","volume":"20","author":"ALI F.","year":"2011","journal-title":"Infectious Disease Journal of Pakistan."},{"issue":"2","key":"ref11","article-title":"Male-female differences in the number of reported incident dengue fever cases in six Asian countries","volume":"2","author":"ANKER M.","year":"2011","journal-title":"Western Pacific Surveillance and Response Journal : WPSAR"},{"issue":"4","key":"ref12","first-page":"685","article-title":"Radiological appearance and their significance in the management of dengue hemorrhagic fever","volume":"5","author":"ASGHAR J.","year":"2011","journal-title":"Pakistan Journal of Medical & Health Sciences"},{"issue":"4","key":"ref13","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3109\/00365548.2013.877155","article-title":"Deaths due to dengue fever at a tertiary care hospital in Lahore, Pakistan","volume":"46","author":"ASSIR M.Z.K.","year":"2014","journal-title":"Scandinavian Journal of Infectious Diseases"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ijid.2013.09.007","article-title":"Concurrent dengue and malaria infection in Lahore, Pakistan during the 2012 dengue outbreak","volume":"18","author":"ASSIR M.Z.K.","year":"2014","journal-title":"International Journal of Infectious Diseases"},{"issue":"3","key":"ref15","first-page":"92","article-title":"Serotyping of dengue virus from deadly outbreaks of Pakistan","volume":"3","author":"ATIF M.","year":"2016","journal-title":"Journal of Human Virology & Retrovirology"},{"issue":"10","key":"ref16","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.apjtm.2016.07.033","article-title":"Meteorological influences on dengue transmission in Pakistan","volume":"9","author":"ATIQUE S.","year":"2016","journal-title":"Asian Pacific Journal of Tropical Medicine"},{"issue":"1","key":"ref17","first-page":"42","article-title":"Predominance of DEN-3 genotype during the recent dengue outbreak in Bangladesh","volume":"33","author":"AZIZ M.M.","year":"2002","journal-title":"The Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/00007890-201007272-00736","article-title":"Dengue Viral Infection in Renal Transplant Recipients in Karachi Pakistan","volume":"90","author":"BAQI S.","year":"2010","journal-title":"Transplantation"},{"issue":"12","key":"ref19","article-title":"Cross-reactivity of rapid Salmonella Typhi IgM immunoassay in dengue fever without co-existing infection","volume":"7","author":"BHATTI A.B.","year":"2015","journal-title":"Cureus"},{"key":"ref20","first-page":"5","article-title":"Survival analysis of dengue patients of Pakistan","volume":"83","author":"CHAUDHRY K.A.","year":"2018","journal-title":"International Journal of Mosquito Research"},{"issue":"4","key":"ref21","doi-asserted-by":"crossref","first-page":"899","DOI":"10.4269\/ajtmh.16-0608","article-title":"Dengue epidemic in post conflict swat district, Khyber Pakhtunkhwa, Pakistan, 2013","volume":"96","author":"CHAUDHRY M.","year":"2017","journal-title":"The American Journal of Tropical Medicine and Hygiene"},{"key":"ref22","series-title":"Climate change indicators of Pakistan.","first-page":"1","author":"CHAUDHRY Q.U.Z.","year":"2009"},{"key":"ref23","article-title":"Drinking water quality status and contamination in Pakistan","volume":"2017","author":"DAUD M.K.","year":"2017","journal-title":"BioMed Research International"},{"issue":"1","key":"ref24","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/1471-2180-11-200","article-title":"Serotype and genotype analysis of dengue virus by sequencing followed by phylogenetic analysis using samples from three mini outbreaks-2007-2009 in Pakistan","volume":"11","author":"FATIMA Z.","year":"2011","journal-title":"BMC Microbiology"},{"issue":"9","key":"ref25","doi-asserted-by":"crossref","first-page":"594","DOI":"10.26719\/2017.23.9.594","article-title":"Multiplex polymerase chain reaction-based serotype analysis of dengue virus during 2015 dengue outbreak in Pakistan","volume":"23","author":"GHANI E.","year":"2017","journal-title":"Eastern Mediterranean Health Journal"},{"issue":"1","key":"ref26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-7622-2-1","article-title":"Dengue fever: new paradigms for a changing epidemiology","volume":"2","author":"GUHA-SAPIR D.","year":"2005","journal-title":"Emerging Themes in Epidemiology"},{"issue":"1","key":"ref27","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/1743-422X-3-92","article-title":"The changing epidemiology of dengue in Delhi, India","volume":"3","author":"GUPTA E.","year":"2006","journal-title":"Virology Journal"},{"issue":"2","key":"ref28","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.jiph.2018.10.138","article-title":"Dengue outbreak in Peshawar: clinical features and laboratory markers of dengue virus infection","volume":"12","author":"HAROON M.","year":"2019","journal-title":"Journal of Infection and Public Health"},{"issue":"1","key":"ref29","first-page":"115","article-title":"Characteristics and outcome of dengue infection; clinical perspective from a secondary care hospital of Karachi","volume":"29","author":"HASAN S.R.","year":"2013","journal-title":"Pakistan Journal of Medical Sciences"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"e54","DOI":"10.1016\/j.ijid.2009.10.008","article-title":"Multiple dengue serotypes and high frequency of dengue haemorrhagic fever at two tertiary care hospitals in Lahore during the 2008 dengue virus outbreak in Punjab, Pakistan","volume":"14","author":"HUMAYOUN M.A.","year":"2010","journal-title":"International Journal of Infectious Diseases"},{"issue":"4","key":"ref31","doi-asserted-by":"crossref","first-page":"307","DOI":"10.5099\/aj120400307","article-title":"Dengue virus serotype 2 (DEN-2): the causative agent of 2011-dengue epidemic in Pakistan","volume":"4","author":"IDREES M.","year":"2012","journal-title":"American Journal of Biomedical Sciences"},{"issue":"4","key":"ref32","doi-asserted-by":"crossref","first-page":"963","DOI":"10.12669\/pjms.334.13026","article-title":"Profile of hepatic involvement in dengue infections in adult Pakistani population","volume":"33","author":"IQTADAR S.","year":"2017","journal-title":"Pakistan Journal of Medical Sciences"},{"issue":"5","key":"ref33","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.12669\/pjms.335.13051","article-title":"Clinical audit of dengue related deaths in 2011- Mayo Hospital Lahore Pakistan","volume":"33","author":"IQTADAR S.","year":"2017","journal-title":"Pakistan Journal of Medical Sciences"},{"issue":"12","key":"ref34","article-title":"Acute Hepatitis in Infections Caused by Dengue Virus in Southern Punjab, Pakistan","volume":"10","author":"ISHTIAQ R.","year":"2018","journal-title":"Cureus"},{"key":"ref35","first-page":"59","article-title":"Clinical and biochemical characteristics of suspected dengue fever in an ambulatory care family medical clinic, Aga Khan University, Karachi, Pakistan","volume":"35","author":"JAHAN F.","year":"2011","journal-title":"Dengue Bulletin"},{"issue":"1","key":"ref36","first-page":"1","article-title":"Prevalence of all four dengue virus serotypes confirmed by using real time RT-PCR among population of Lahore Pakistan","volume":"3","author":"JAVED F.T.","year":"2009","journal-title":"International Journal of Livestock Research"},{"issue":"1","key":"ref37","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1186\/1756-0500-7-473","article-title":"Predictors of hospital stay and mortality in dengue virus infection-experience from Aga Khan University Hospital Pakistan","volume":"7","author":"KHALIL M.A.M.","year":"2014","journal-title":"BMC Research Notes"},{"issue":"2","key":"ref38","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.jcv.2008.06.003","article-title":"Co-circulations of two genotypes of dengue virus in 2006 out-break of dengue hemorrhagic fever in Karachi, Pakistan","volume":"43","author":"KHAN E.","year":"2008","journal-title":"Journal of Clinical Virology"},{"issue":"9","key":"ref39","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0012505","article-title":"Demographic and clinical features of dengue fever in Pakistan from 2003-2007: a retrospective cross-sectional study","volume":"5","author":"KHAN E.","year":"2010","journal-title":"PLoS One"},{"issue":"11","key":"ref40","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1016\/j.trstmh.2007.06.016","article-title":"Dengue outbreak in Karachi, Pakistan, 2006: experience at a tertiary care center","volume":"10","author":"KHAN E.","year":"2007","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"6","key":"ref41","doi-asserted-by":"crossref","first-page":"876","DOI":"10.29309\/TPMJ\/2018.25.06.274","article-title":"Dengue Fever. Role of non-structural protein-1 (NS-1) positivity in dengue cases: an experience from a Qazi Hussain Ahmed Medical Complex Nowshera","volume":"25","author":"KHAN H.","year":"2018","journal-title":"The Professional Medical Journal"},{"issue":"1","key":"ref42","first-page":"10632","article-title":"Outbreak investigation of dengue fever in District Malir, Karachi, Sindh, Pakistan, 2015","volume":"4","author":"KHAN J.","year":"2018","journal-title":"I Proceedings"},{"issue":"1","key":"ref43","first-page":"1","article-title":"Incidence of dengue in 2013: dengue outbreak in District Swat, Khyber Pakhtunkhwa, Pakistan","volume":"2","author":"KHAN J.","year":"2015","journal-title":"International Journal of Fauna and Biological Studies"},{"issue":"4","key":"ref44","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0195706","article-title":"The changing epidemiological pattern of Dengue in Swat, Khyber Pakhtunkhwa","volume":"13","author":"KHAN J.","year":"2018","journal-title":"PLoS One"},{"issue":"3","key":"ref45","first-page":"51","article-title":"Experience with dengue in tertiary Care Centre","volume":"19","author":"KHAN M.","year":"2013","journal-title":"Medical Channel"},{"issue":"3","key":"ref46","article-title":"Emergence and diversification of dengue 2 cosmopolitan genotype in Pakistan, 2011","volume":"8","author":"KHAN M.A.","year":"2013","journal-title":"PLoS One"},{"issue":"1","key":"ref47","article-title":"Factors predicting severe dengue in patients with dengue fever","volume":"5","author":"KHAN M.I.H.","year":"2013","journal-title":"Mediterranean Journal of Hematology and Infectious Diseases"},{"issue":"10","key":"ref48","first-page":"1466","article-title":"Dengue fever. The clinical pattern and mortality in epidemic and post epidemic years in Swat","volume":"24","author":"KHAN W.","year":"2017","journal-title":"The Professional Medical Journal"},{"issue":"4","key":"ref49","first-page":"479","article-title":"An epidemiological study of patients admitted with viral hemorrhagic fever (VHF): a single center experience","volume":"42","author":"KHAN W.M.","year":"2017","journal-title":"Rawal Medical Journal"},{"issue":"6","key":"ref50","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.jiph.2014.05.005","article-title":"Dengue hemorrhagic fever: comparison of patients with primary and secondary infections","volume":"7","author":"KHURRAM M.","year":"2014","journal-title":"Journal of Infection and Public Health"},{"issue":"1","key":"ref51","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1186\/1743-422X-10-275","article-title":"Evolution and heterogeneity of multiple serotypes of Dengue virus in Pakistan, 2006\u20132011","volume":"10","author":"KOO C.","year":"2013","journal-title":"Virology Journal"},{"issue":"1","key":"ref52","doi-asserted-by":"crossref","first-page":"172","DOI":"10.12669\/pjms.331.11237","article-title":"Evaluation of Non-Structural Protein-1 (NS1) positive patients of 2013 dengue outbreak in Khyber Pakhtunkhwa, Pakistan","volume":"33","author":"LUTFULLAH G.","year":"2017","journal-title":"Pakistan Journal of Medical Sciences"},{"issue":"1","key":"ref53","first-page":"52","article-title":"Dermatological manifestations of dengue fever","volume":"24","author":"MAHBOOB A.","year":"2012","journal-title":"Journal of Ayub Medical College, Abbottabad"},{"issue":"3","key":"ref54","first-page":"93","article-title":"Incidence of dengue haemorrhagic fever in local population of Lahore, Pakistan","volume":"25","author":"MAHMOOD K.","year":"2009","journal-title":"Biomedica"},{"issue":"1","key":"ref55","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1097\/MAJ.0b013e3182217001","article-title":"Prevalence and molecular characterization of dengue viruses serotypes in 2010 epidemic","volume":"343","author":"MAHMOOD N.","year":"2012","journal-title":"The American Journal of the Medical Sciences"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/139273","article-title":"Does comorbidity increase the risk of dengue hemorrhagic fever and dengue shock syndrome?","volume":"2013","author":"MAHMOOD S.","year":"2013","journal-title":"ISRN Tropical Medicine"},{"issue":"5","key":"ref57","first-page":"553","article-title":"Dengue fever in patients admitted in tertiary care hospitals in Pakistan","volume":"64","author":"MUNIR M.A.","year":"2014","journal-title":"Journal of the Pakistan Medical Association"},{"key":"ref58","first-page":"299","article-title":"Epidemiology of dengue: past, present and future prospects","volume":"5","author":"MURRAY N.E.A.","year":"2013","journal-title":"Clinical Epidemiology"},{"issue":"2","key":"ref59","doi-asserted-by":"crossref","first-page":"243","DOI":"10.29309\/TPMJ\/2014.21.02.1972","article-title":"Dengue fever: a clinical experience","volume":"21","author":"NAEEM M.","year":"2018","journal-title":"The Professional Medical Journal"},{"key":"ref60","first-page":"204","article-title":"Dengue fever outbreak in Lahore, Pakistan: a clinical management experience","volume":"3","author":"NAZEER A.","year":"2009","journal-title":"Pakistan Journal of Medical & Health Sciences"},{"issue":"1","key":"ref61","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/1471-230X-10-43","article-title":"Severity of acute hepatitis and its outcome in patients with dengue fever in a tertiary care hospital Karachi, Pakistan (South Asia)","volume":"10","author":"PARKASH O.","year":"2010","journal-title":"BMC Gastroenterology"},{"issue":"1","key":"ref62","first-page":"9","article-title":"Relationship between serum lactate dehydrogenase levels and dengue severity","volume":"21","author":"PERVEEN S.","year":"2016","journal-title":"Journal of Rawalpindi Medical College"},{"issue":"1","key":"ref63","first-page":"4","article-title":"Epidemiological surveillance of dengue infections: a community based study in rural, Karachi (2010-2012)","volume":"20","author":"QUADRI S.M.A.","year":"2015","journal-title":"Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College"},{"key":"ref64","series-title":"The groundwater economy of Pakistan.","author":"QURESHI A.S.","year":"2003"},{"issue":"10","key":"ref65","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/j.apjtm.2017.09.013","article-title":"Asymptomatic dengue infection in adults of major cities of Pakistan","volume":"10","author":"RAFIQUE I.","year":"2017","journal-title":"Asian Pacific Journal of Tropical Medicine"},{"issue":"3","key":"ref66","first-page":"256","article-title":"Economic burden of dengue in four major cities of Pakistan during 2011","volume":"65","author":"RAFIQUE I.","year":"2015","journal-title":"JPMA"},{"issue":"5","key":"ref67","doi-asserted-by":"crossref","first-page":"661","DOI":"10.29309\/TPMJ\/2012.19.05.2330","article-title":"Dengue hemorrhagic fever\/dengue shock syndrome","volume":"19","author":"RASHID A.","year":"2012","journal-title":"The Professional Medical Journal"},{"issue":"2","key":"ref68","first-page":"50","article-title":"Epidemiological features of dengue fever in a four-year hospital based study in Faisalabad, Pakistan","volume":"11","author":"RAZA F.A.","year":"2017","journal-title":"Journal of Fatima Jinnah Medical University."},{"issue":"4","key":"ref69","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1590\/0037-8682-0246-2017","article-title":"Dengue seroprevalence and its socioeconomic determinants in Faisalabad, Pakistan: a cross-sectional study","volume":"51","author":"RAZA F.A.","year":"2018","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"3","key":"ref70","article-title":"Demographic and clinico-epidemiological features of dengue fever in Faisalabad, Pakistan","volume":"9","author":"RAZA F.A.","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"ref71","first-page":"496","article-title":"Clinical and laboratory profile of dengue fever patients admitted in combined military hospital rawalpindi in year 2015","volume":"67","author":"REHMAN M.M.U.","year":"2017","journal-title":"Pakistan Armed Forces Medical Journal"},{"issue":"6","key":"ref72","first-page":"339","article-title":"Outbreak of dengue fever in Karachi 2006: a clinical perspective","volume":"59","author":"RIAZ M.M.","year":"2009","journal-title":"Journal of the Pakistan Medical Association"},{"issue":"1","key":"ref73","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1186\/1756-0500-7-205","article-title":"A retrospective analysis of dengue fever case management and frequency of co-morbidities associated with deaths","volume":"7","author":"SAQIB M.A.N.","year":"2014","journal-title":"BMC Research Notes"},{"issue":"4","key":"ref74","first-page":"93","article-title":"Persistence of dengue symptoms among discharged dengue cases of Lahore, Pakistan","volume":"53","author":"SAQIB M.A.N.","year":"2014","journal-title":"Pakistan Journal of Medical Research"},{"issue":"5","key":"ref75","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.17582\/journal.pjz\/2019.51.5.sc4","article-title":"Comparative analysis of immunological and genomic outcomes of dengue virus outbreak in Pakistan","volume":"51","author":"SHAHID M.","year":"2019","journal-title":"Pakistan Journal of Zoology"},{"issue":"3","key":"ref76","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S1015-9584(10)60019-X","article-title":"Frequency, pattern and management of acute abdomen in dengue fever in Karachi, Pakistan","volume":"33","author":"SHAMIM M.","year":"2010","journal-title":"Asian Journal of Surgery"},{"issue":"4","key":"ref77","first-page":"325","article-title":"Skin involvement in patients of dengue fever during the 2011 epidemic in Lahore, Pakistan","volume":"22","author":"SHEIKH K.R.","year":"2012","journal-title":"Journal of Pakistan Association of Dermatologists"},{"issue":"4","key":"ref78","doi-asserted-by":"crossref","first-page":"1","DOI":"10.26634\/jnur.4.4.3071","article-title":"Dengue more prevalent than previously thought: an epidemiology approach","volume":"4","author":"SULAIMAN S.","year":"2015","journal-title":"i-Manager\u2019s Journal on Nursing"},{"issue":"4","key":"ref79","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.apjtm.2016.03.010","article-title":"Dengue outbreak in Swat and Mansehra, Pakistan 2013: an epidemiological and diagnostic perspective","volume":"9","author":"SULEMAN M.","year":"2016","journal-title":"Asian Pacific Journal of Tropical Medicine"},{"issue":"1","key":"ref80","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/s40249-017-0258-6","article-title":"Preliminary Seroepidemiological survey of dengue infections in Pakistan, 2009-2014","volume":"6","author":"SULEMAN M.","year":"2017","journal-title":"Infectious Diseases of Poverty"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.actatropica.2017.02.011","article-title":"Outbreak of dengue virus type-3 in Malakand, Pakistan 2015; A laboratory perspective","volume":"169","author":"SULEMAN M.","year":"2017","journal-title":"Acta Tropica"},{"issue":"3","key":"ref82","first-page":"122","article-title":"Outbreak of dengue fever in Mangla and Mirpur area","volume":"17","author":"TARIQ W.Z.","year":"2006","journal-title":"Pakistan Journal of Pathology"},{"issue":"1","key":"ref83","first-page":"70","article-title":"Outcome of dengue fever in adults","volume":"9","author":"USMAN M.","year":"2011","journal-title":"Gomal Journal of Medical Sciences."},{"issue":"9","key":"ref84","first-page":"488","article-title":"Changing patterns and outcome of Dengue infection; report from a tertiary care hospital in Pakistan","volume":"58","author":"WASAY M.","year":"2008","journal-title":"The Journal of the Pakistan Medical Association"},{"issue":"6","key":"ref85","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.clineuro.2008.03.011","article-title":"Encephalitis and myelitis associated with dengue viral infection: clinical and neuroimaging features","volume":"110","author":"WASAY M.","year":"2008","journal-title":"Clinical Neurology and Neurosurgery"},{"issue":"1","key":"ref86","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4103\/1995-7645.223529","article-title":"Scenario of dengue infection & its control in Pakistan: an up\u2014date and way forward","volume":"11","author":"YOUSAF M.Z.","year":"2018","journal-title":"Asian Pacific Journal of Tropical Medicine"},{"issue":"11","key":"ref87","first-page":"12","article-title":"Seroprevalence of dengue fever (IgG) in adults of Rawalpindi district","volume":"4","author":"ZAFAR H.","year":"2013","journal-title":"Population"},{"issue":"1","key":"ref88","first-page":"13","article-title":"Seroprevalence of dengue viral infection in healthy population residing in rural areas of District Rawalpindi","volume":"8","author":"ZAFAR H.","year":"2010","journal-title":"International Journal of Pathology"},{"issue":"2","key":"ref89","doi-asserted-by":"crossref","first-page":"A374","DOI":"10.1093\/ajcp\/138.suppl2.212","article-title":"Dengue: a myth or reality","volume":"138","author":"ZAMIR Q.","year":"2012","journal-title":"American Journal of Clinical Pathology"}],"container-title":["Brazilian Journal of Biology"],"original-title":["Carga e distribui\u00e7\u00e3o geral de infec\u00e7\u00e3o por dengue no Paquist\u00e3o entre 2000 e 2019: uma revis\u00e3o"],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S1519-69842024000100701&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T09:17:01Z","timestamp":1729243021000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1519-69842024000100701&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":89,"alternative-id":["S1519-69842024000100701"],"URL":"https:\/\/doi.org\/10.1590\/1519-6984.267982","relation":{},"ISSN":["1678-4375","1519-6984"],"issn-type":[{"value":"1678-4375","type":"electronic"},{"value":"1519-6984","type":"print"}],"subject":[],"published":{"date-parts":[[2024]]},"article-number":"e267982"}}