{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T11:27:06Z","timestamp":1787916426720,"version":"build-2784847793"},"reference-count":31,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. J. Biol."],"abstract":"<jats:p>Abstract The search for meat-based foods, even if it allows to increase the shelf life of commercialized foods, can lead to contamination by pathogenic microorganisms. In this sense, the present study aimed to test the potential antibacterial effect of Thymus vulgaris (thyme) essential oil against food-borne strains of the bacterium Escherichia coli. Therefore, the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) analyses were performed on microdilution plates. In addition, the study of the association of the product with synthetic antimicrobials, performed by the disk diffusion technique, as well as the antiadherent activity, which was determined in the presence of sucrose, in glass tubes. Therefore, thyme oil showed a strong inhibitory activity, as well as a bactericidal effect against Escherichia coli strains, with MIC and MBC values equal to 512 \u03bcg\/mL for all strains analyzed. Furthermore, T. vulgaris oil exhibited interactions in the association, with an antagonistic effect for most antibacterials. Regarding antiadherence activity, the test product was effective in inhibiting the adhesion of the bacterial strains under study and presented a more significant effect than 0.12% chlorhexidine digluconate. Thus, thyme oil presented an antibacterial result against E. coli, being a natural product that may represent a promising alternative in the fight against foodborne diseases.<\/jats:p>","DOI":"10.1590\/1519-6984.292165","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T11:38:34Z","timestamp":1748259514000},"source":"Crossref","is-referenced-by-count":3,"title":["Antibacterial potential of Thymus vulgaris (Thyme) oil against Escherichia coli strains isolated from food"],"prefix":"10.1590","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1787-4316","authenticated-orcid":false,"given":"L.","family":"Brito-Junior","sequence":"first","affiliation":[{"name":"Universidade Federal de Campina Grande,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2624-3486","authenticated-orcid":false,"given":"H. C.","family":"Brito","sequence":"additional","affiliation":[{"name":"Universidade Federal da Para\u00edba,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0654-4733","authenticated-orcid":false,"given":"M. M.","family":"Sim\u00f5es","sequence":"additional","affiliation":[{"name":"Universidade Federal de Campina Grande,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0843-2142","authenticated-orcid":false,"given":"J. H. A.","family":"Farias","sequence":"additional","affiliation":[{"name":"Universidade Federal de Campina Grande,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4234-4752","authenticated-orcid":false,"given":"B.","family":"Santos","sequence":"additional","affiliation":[{"name":"Universidade Federal de Campina Grande,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5571-1596","authenticated-orcid":false,"given":"F. M .C.","family":"Marques","sequence":"additional","affiliation":[{"name":"Universidade Federal de Campina Grande,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5563-7955","authenticated-orcid":false,"given":"M. A. 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F.","family":"Diniz","sequence":"additional","affiliation":[{"name":"Universidade Federal de Campina Grande,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9891-7842","authenticated-orcid":false,"given":"V. L. R.","family":"Vilela","sequence":"additional","affiliation":[{"name":"Universidade Federal de Campina Grande,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7466-9933","authenticated-orcid":false,"given":"A.","family":"Oliveira-Filho","sequence":"additional","affiliation":[{"name":"Universidade Federal de Campina Grande,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2025]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1186\/s12866-019-1590-8","article-title":"Escherichia coli O157:H7: distribution, molecular characterization, antimicrobial resistance patterns and source of contamination of sheep and goat carcasses at an export abattoir, Mojdo, Ethiopia","volume":"19","author":"ABREHAM S.","year":"2019","journal-title":"BMC 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Microbiology"},{"key":"ref27","article-title":"Evaluation of the antimicrobial activity of Eucalyptus radiata essential oil against Escherichia coli strains isolated from meat products","volume":"84","author":"SANTOS B.","year":"2024","journal-title":"Brazilian Journal of Biology = Revista Brasileira de Biologia"},{"issue":"4","key":"ref28","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1590\/S1517-83822004000300001","article-title":"Composition and antimicrobial activity of essential oils from aromatic plants used in Brazil","volume":"35","author":"SARTORATTO A.","year":"2004","journal-title":"Brazilian Journal of Microbiology"},{"issue":"12","key":"ref29","doi-asserted-by":"crossref","first-page":"2446","DOI":"10.3390\/microorganisms10122446","article-title":"Towards green strategies of food security: antibacterial synergy of essential oils from Thymus vulgaris and Syzygium aromaticum to inhibit Escherichia coli and Staphylococcus aureus pathogenic food isolates","volume":"10","author":"SATERIALE D.","year":"2022","journal-title":"Microorganisms"},{"issue":"23","key":"ref30","doi-asserted-by":"crossref","first-page":"3920","DOI":"10.3390\/plants12233920","article-title":"Thymus zygis, valuable antimicrobial (in vitro and in situ) and antibiofilm agent with potential antiproliferative effects","volume":"12","author":"VUKI\u0106 M.D.","year":"2023","journal-title":"Plants"},{"key":"ref31","series-title":"Trabalhando juntos para combater a resist\u00eancia aos antimicrobianos","year":"2021"}],"container-title":["Brazilian Journal of Biology"],"original-title":["Potencial antibacteriano do \u00f3leo de Thymus vulgaris (tomilho) contra cepas de Escherichia coli isoladas de alimentos"],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S1519-69842025000100211&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T11:38:39Z","timestamp":1748259519000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1519-69842025000100211&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":31,"alternative-id":["S1519-69842025000100211"],"URL":"https:\/\/doi.org\/10.1590\/1519-6984.292165","relation":{},"ISSN":["1678-4375","1519-6984"],"issn-type":[{"value":"1678-4375","type":"electronic"},{"value":"1519-6984","type":"print"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"e292165"}}