{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T04:34:48Z","timestamp":1792211688818,"version":"4.4.0"},"reference-count":46,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Braz. J. Biol."],"abstract":"<jats:p>Abstract Brazil is one of the countries for which the World Health Organization (WHO) has set the goal of eliminating schistosomiasis as a public health problem by 2030. However, the current scenario shows that 19 out of the 26 Brazilian states are still affected by the disease. This study aimed to assess the positivity rate, parasite load, and risk factors associated with Schistosoma mansoni infection in the population, as well as to identify potential risk areas for parasite transmission in a municipality in Northeastern Brazil. A cross-sectional study was conducted between January and October 2023 in the municipality of Feira Grande, Alagoas. To determine S. mansoni positivity and parasite burden, the Kato-Katz coproparasitological method was used, with four slides analyzed per participant, in addition to a questionnaire to identify risk factors. Intermediate host snails were also collected and examined for trematode infection. Spatial analysis was used to identify risk areas, and both univariate and multivariate logistic regression were applied to evaluate the association between infection and risk factors. The overall positivity rate was 5.5% (n=20), with 90% (n=18) of infected individuals presenting with low parasite loads. In the univariate analysis, predictors of S. mansoni infection included age between 25 and 64 years, marital status (married or widowed), occupation as a farmer, and the use of water sources such as dams, ponds, reservoirs, wells, or cisterns. After adjustment for confounding factors, only occupation as a farmer remained significantly associated with an increased risk of infection. Of the 22 water collections identified, 12 were classified as breeding sites, and one was considered a transmission focus based on the detection of an infected Biomphalaria glabrata specimen. Four risk areas were identified, two of which were breeding sites for Biomphalaria straminea, and one for B. glabrata. Despite the low positivity rate, all conditions necessary for maintaining the parasite\u2019s life cycle were present, associated with both population behavior and the existence of breeding and transmission foci. Our findings indicate that understanding the specific characteristics of endemic areas is crucial for developing locally adapted prevention and control strategies.<\/jats:p>","DOI":"10.1590\/1519-6984.292478","type":"journal-article","created":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:07:19Z","timestamp":1761577639000},"source":"Crossref","is-referenced-by-count":1,"title":["Diagnosis and risk factors associated with Schistosoma mansoni infection in a population of an endemic area of Northeastern Brazil"],"prefix":"10.1590","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9958-9331","authenticated-orcid":false,"given":"R. E. S.","family":"Ramos","sequence":"first","affiliation":[{"name":"Universidade Federal de Pernambuco,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6375-633X","authenticated-orcid":false,"given":"L. P.","family":"Bezerra","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5616-1597","authenticated-orcid":false,"given":"M. W. S.","family":"Lima","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Alagoas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9031-7850","authenticated-orcid":false,"given":"W. 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C.","family":"Silva","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Alagoas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4580-1086","authenticated-orcid":false,"given":"M. P.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Alagoas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7718-976X","authenticated-orcid":false,"given":"M. M. V.","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Alagoas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1943-5189","authenticated-orcid":false,"given":"S. C.","family":"Gomes","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Alagoas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2898-2646","authenticated-orcid":false,"given":"W. S.","family":"Paz","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pernambuco,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2713-1989","authenticated-orcid":false,"given":"L. O.","family":"Silva","sequence":"additional","affiliation":[{"name":"Universidade Federal de Sergipe,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9468-2986","authenticated-orcid":false,"given":"A. P.","family":"Lima-J\u00fanior","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Alagoas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4934-0044","authenticated-orcid":false,"given":"A. P. S.","family":"Feitosa","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8384-3008","authenticated-orcid":false,"given":"L. C.","family":"Alves","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5210-6697","authenticated-orcid":false,"given":"I. G. 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a population in an area of low transmission","volume":"108","author":"ENK M.J.","year":"2008","journal-title":"Acta Tropica"},{"key":"ref12","series-title":"eTrex\u00ae 20x","year":"2024"},{"issue":"4","key":"ref13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001603","article-title":"A research agenda for helminth diseases of humans: social ecology, environmental determinants, and health systems","volume":"6","author":"GAZZINELLI A.","year":"2012","journal-title":"PLoS Neglected Tropical Diseases"},{"issue":"4","key":"ref14","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1590\/1980-5497201600040012","article-title":"Transmiss\u00e3o urbana da esquistossomose: novo cen\u00e1rio epidemiol\u00f3gico na Zona da Mata de Pernambuco","volume":"19","author":"GOMES E.C.S.","year":"2016","journal-title":"Revista Brasileira de Epidemiologia"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2023-013439","article-title":"Mass drug 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individuals from an endemic area with low parasite loads","volume":"147","author":"MAGALH\u00c3ES F.C.","year":"2020","journal-title":"Parasitology"},{"key":"ref26","article-title":"Limnic gastropods and trematodes of public health concern in Barreirinhas, Maranh\u00e3o State, Brazil","volume":"84","author":"MARQUES A.M.","year":"2025","journal-title":"Brazilian Journal of Biology = Revista Brasileira de Biologia"},{"key":"ref27","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1268998","article-title":"FioSchisto\u2019s expert perspective on implementing WHO guidelines for schistosomiasis control and transmission elimination in Brazil","volume":"14","author":"MENEZES C.A.","year":"2023","journal-title":"Frontiers in Immunology"},{"issue":"2","key":"ref28","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0014-4894(56)90008-X","article-title":"A method for estimating the density of aquatic snail populations","volume":"5","author":"OLIVIER L.","year":"1956","journal-title":"Experimental Parasitology"},{"issue":"1","key":"ref29","first-page":"88","article-title":"Observation on the morfology of Australorbis glabratus","volume":"53","author":"PARAENSE W.L.","year":"1955","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz"},{"issue":"4","key":"ref30","first-page":"369","article-title":"Larvas de tremat\u00f3deos em moluscos do Brasil: panorama e perspectivas ap\u00f3s um s\u00e9culo de estudos","volume":"42","author":"PINTO H.A.","year":"2014","journal-title":"Revista de Patologia Tropical"},{"issue":"3","key":"ref31","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1590\/S1984-29612013000300019","article-title":"Petasiger Dietz, 1909 (Trematoda: Echinostomatidae) in birds and mollusks from Brazil","volume":"22","author":"PINTO H.A.","year":"2013","journal-title":"Revista Brasileira de Parasitologia Veterin\u00e1ria"},{"issue":"2","key":"ref32","first-page":"27","article-title":"Aspectos epidemiol\u00f3gicos e distribui\u00e7\u00e3o dos casos de infec\u00e7\u00e3o pelo Schistosoma mansoni em munic\u00edpios do Estado de Alagoas, Brasil","volume":"7","author":"ROCHA T.J.M.","year":"2016","journal-title":"Revista Pan-Amazonica de Saude"},{"key":"ref33","article-title":"New epidemiological profile of schistosomiasis from an area of low prevalence in Brazil","volume":"53","author":"SANTOS I.G.A.","year":"2020","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"9","key":"ref34","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1111\/tmi.13458","article-title":"Analysis and spatial distribution of schistosomiasis mansoni in a historically endemic area of northeastern Brazil","volume":"25","author":"SANTOS I.G.A.","year":"2020","journal-title":"Tropical Medicine & International Health"},{"issue":"2","key":"ref35","article-title":"Aspectos relacionados com a positividade para a esquistossomose: estudo transversal em \u00e1rea de baixa preval\u00eancia em Alagoas, 2020","volume":"30","author":"SANTOS I.G.A.","year":"2021","journal-title":"Epidemiologia e Servi\u00e7os de Sa\u00fade: Revista do Sistema \u00danico de Sa\u00fade do Brasil"},{"key":"ref36","doi-asserted-by":"crossref","DOI":"10.1590\/0037-8682-0458-2018","article-title":"Schistosomiasis mansoni in the northeast region of Brazil: temporal modeling of positivity, hospitalization,and mortality rates","volume":"52","author":"SILVA L.F.","year":"2019","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"issue":"2","key":"ref37","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1590\/0074-02760140375","article-title":"Evaluation of parasitological and molecular techniques for the diagnosis and assessment of cure of schistosomiasis mansoni in a low transmission area","volume":"110","author":"SIQUEIRA L.M.V.","year":"2015","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz"},{"issue":"1","key":"ref38","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1590\/S0074-02761995000100003","article-title":"Degree of host-parasite compatibility between Schistosoma mansoni and their intermediate molluscan hosts in Brazil","volume":"90","author":"SOUZA C.P.","year":"1995","journal-title":"Memorias do Instituto Oswaldo Cruz"},{"issue":"3","key":"ref39","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1590\/S0037-86822008000300006","article-title":"Criadouros de Biomphalaria, tempor\u00e1rios e permanentes, em Jaboat\u00e3o dos Guararapes, PE","volume":"41","author":"SOUZA M.A.A.","year":"2008","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical"},{"key":"ref40","first-page":"1375","article-title":"Schistosoma mansoni in the context of the Brazilian health policy","volume":"16","author":"TIBIRI\u00c7\u00c1 S.H.C.","year":"2011","journal-title":"Ci\u00eancia & Sa\u00fade Coletiva"},{"issue":"10","key":"ref41","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1017\/S0031182022000385","article-title":"Neglected food-borne trematodiases: echinostomiasis and gastrodiscoidiasis","volume":"149","author":"TOLEDO R.","year":"2022","journal-title":"Parasitology"},{"issue":"4","key":"ref42","doi-asserted-by":"crossref","first-page":"e366","DOI":"10.1016\/S2666-5247(23)00377-4","article-title":"Diagnostic tests for human Schistosoma mansoni and Schistosoma haematobium infection: a systematic review and meta-analysis","volume":"5","author":"VAILLANT M.T.","year":"2024","journal-title":"The Lancet Microbe"},{"key":"ref43","series-title":"Prevention and control of schistosomiasis and soil-transmitted helminthiasis: report of a WHO expert committee.","year":"2002","edition":"1st"},{"key":"ref44","series-title":"Schistosomiasis","year":"2022"},{"key":"ref45","series-title":"WHO guideline on control and elimination of human schistosomiasis.","year":"2022","edition":"1st"},{"key":"ref46","series-title":"Ending the neglect to attain the Sustainable Development Goals: a rationale for continued investment in tackling neglected tropical diseases 2021-2030.","year":"2022","edition":"1st"}],"container-title":["Brazilian Journal of Biology"],"original-title":["Diagn\u00f3stico e fatores de risco associados \u00e0 infec\u00e7\u00e3o por Schistosoma mansoni em uma popula\u00e7\u00e3o de \u00e1rea end\u00eamica do Nordeste do Brasil"],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S1519-69842025000100369&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:07:27Z","timestamp":1761577647000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1519-69842025000100369&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":46,"alternative-id":["S1519-69842025000100369"],"URL":"https:\/\/doi.org\/10.1590\/1519-6984.292478","relation":{},"ISSN":["1678-4375","1519-6984"],"issn-type":[{"value":"1678-4375","type":"electronic"},{"value":"1519-6984","type":"print"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"e292478"}}