{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:09:09Z","timestamp":1791925749569,"version":"4.3.4"},"reference-count":37,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. vasc. bras."],"abstract":"<jats:p>Resumo  Contexto O clampeamento a\u00f3rtico e a oclus\u00e3o da aorta com bal\u00e3o poderiam levar a les\u00f5es na parede a\u00f3rtica.  Objetivo O objetivo deste estudo foi verificar as altera\u00e7\u00f5es da parede a\u00f3rtica relacionadas ao m\u00e9todo de interrup\u00e7\u00e3o de fluxo (cample ou bal\u00e3o) em diferentes t\u00e9cnicas dispon\u00edveis para cirurgia de aorta.  M\u00e9todos Os experimentos foram realizados em 40 porcos f\u00eameas pesando de 25-30 kg, alocados para quatro grupos: S (n = 10), nenhuma interven\u00e7\u00e3o (sham); C (n = 10), laparotomia mediana transperitoneal para acesso \u00e0 aorta abdominal infrarrenal com tempo de clampeamento de 60 minutos; L (n = 10), cirurgia laparosc\u00f3pica da aorta abdominal infrarrenal com tempo de clampeamento de 60 minutos; EV (n = 10), controle a\u00f3rtico proximal com inser\u00e7\u00e3o de cateter-bal\u00e3o para oclus\u00e3o a\u00f3rtica por acesso femoral, inflado a fim de promover oclus\u00e3o a\u00f3rtica cont\u00ednua por 60 minutos. Ap\u00f3s a eutan\u00e1sia, as aortas foram removidas e seccionadas para obten\u00e7\u00e3o de esp\u00e9cimes histol\u00f3gicos destinados a an\u00e1lises morfom\u00e9tricas e por microscopia de luz. Os fragmentos longitudinais restantes foram estirados at\u00e9 a ruptura, e determinaram-se padr\u00f5es mec\u00e2nicos.  Resultados Observou-se redu\u00e7\u00e3o do limite de proporcionalidade da aorta abdominal, diminui\u00e7\u00e3o da rigidez e da carga de ruptura nos grupos submetidos a campleamento a\u00f3rtico (C e L) em compara\u00e7\u00e3o ao grupo EV.  Conclus\u00f5es O campleamento a\u00f3rtico durante cirurgia aberta ou laparosc\u00f3pica pode afetar as propriedades mec\u00e2nicas da aorta, ocasionando redu\u00e7\u00e3o de resist\u00eancia da parede a\u00f3rtica sem desencadear altera\u00e7\u00f5es na estrutura histol\u00f3gica da parede a\u00f3rtica.<\/jats:p>","DOI":"10.1590\/1677-5449.190025","type":"journal-article","created":{"date-parts":[[2020,4,4]],"date-time":"2020-04-04T19:25:30Z","timestamp":1586028330000},"source":"Crossref","is-referenced-by-count":5,"title":["Les\u00e3o aguda da parede arterial provocada pelo m\u00e9todo de interrup\u00e7\u00e3o tempor\u00e1ria de fluxo em diferentes vias de cirurgia a\u00f3rtica: estudo morfol\u00f3gico e biomec\u00e2nico da aorta de porcos"],"prefix":"10.1590","volume":"19","author":[{"given":"Marcela Polachini","family":"Prata","sequence":"first","affiliation":[{"name":"Universidade Estadual Paulista,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0455-9162","authenticated-orcid":false,"given":"Rodrigo Gibin","family":"Jaldin","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Luiz Toledo de Arruda","family":"Louren\u00e7\u00e3o","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2271-5878","authenticated-orcid":false,"given":"Marcone Lima","family":"Sobreira","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0974-8264","authenticated-orcid":false,"given":"Ricardo de Alvarenga","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Universidade 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