{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:04:49Z","timestamp":1753887889355,"version":"3.41.2"},"reference-count":16,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. vasc. bras."],"abstract":"<jats:p>Resumo A lipodermatoesclerose \u00e9 uma paniculite que se caracteriza por endurecimento e hiperpigmenta\u00e7\u00e3o da pele envolvendo as panturrilhas, com a apar\u00eancia de \u201cgarrafa de champanhe invertida\u201d. Muitas abordagens terap\u00eauticas t\u00eam sido recomendadas, mas o uso de oxandrolona para essa finalidade foi pouco estudado at\u00e9 o momento. Relatamos um caso de lipodermatoesclerose aguda em uma mulher de 61 anos, com hist\u00f3ria pr\u00e9via de tratamento cir\u00fargico para insufici\u00eancia venosa de membros inferiores. A paciente apresentava edema e les\u00f5es dolorosas e eritematosas com infiltra\u00e7\u00e3o difusa, que acometiam principalmente a face posterior da panturrilha esquerda. Foi tratada inicialmente com estanozolol e pentoxifilina, com boa resposta. Devido \u00e0 indisponibilidade do estanozolol, iniciou-se o uso de oxandrolona. Esse tratamento foi bem tolerado, resultando em redu\u00e7\u00e3o significativa do edema, do eritema e da infiltra\u00e7\u00e3o presentes nos membros inferiores, al\u00e9m de al\u00edvio da dor. A oxandrolona pode representar uma op\u00e7\u00e3o \u00fatil e segura no tratamento da lipodermatoesclerose aguda.<\/jats:p>","DOI":"10.1590\/1677-5449.190031","type":"journal-article","created":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T19:28:29Z","timestamp":1573068509000},"source":"Crossref","is-referenced-by-count":4,"title":["Oxandrolona no tratamento da lipodermatoesclerose: relato de caso"],"prefix":"10.1590","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9086-8847","authenticated-orcid":false,"given":"Leonardo Am\u00e9d\u00e9e","family":"P\u00e9ret","sequence":"first","affiliation":[{"name":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heloisa Malaquias","family":"Vidal","sequence":"additional","affiliation":[{"name":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela Alves Cardoso","family":"Gomes","sequence":"additional","affiliation":[{"name":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1810-7888","authenticated-orcid":false,"given":"Gabriel Victor Borba","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lainara Magalh\u00e3es","family":"Aguiar","sequence":"additional","affiliation":[{"name":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2019]]},"reference":[{"issue":"2","key":"ref1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1067\/mjd.2002.119101","article-title":"Lipodermatosclerosis: review of cases evaluated at Mayo Clinic","volume":"46","author":"Bruce 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Las celulitis que nunca fueron","volume":"14","author":"Santana L","year":"2016","journal-title":"Derm CMQ."},{"series-title":"Hereditary angioedema: general care and long-term prophylaxis","author":"Cicardi M","key":"ref15"},{"key":"ref16","first-page":"198","article-title":"Pentoxifilina no tratamento da \u00falcera venosa: uma revis\u00e3o baseada na evid\u00eancia","volume":"32","author":"Neves A","year":"2016","journal-title":"Rev Port Med Geral Fam"}],"container-title":["Jornal Vascular Brasileiro"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/jvb\/v18\/1677-5449-jvb-18-e20190031.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T20:17:37Z","timestamp":1596226657000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1677-54492019000100620&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":16,"alternative-id":["S1677-54492019000100620"],"URL":"https:\/\/doi.org\/10.1590\/1677-5449.190031","relation":{},"ISSN":["1677-7301","1677-5449"],"issn-type":[{"type":"electronic","value":"1677-7301"},{"type":"print","value":"1677-5449"}],"subject":[],"published":{"date-parts":[[2019]]},"article-number":"e20190031"}}