{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T02:23:16Z","timestamp":1767666196839,"version":"3.41.2"},"reference-count":29,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. vasc. bras."],"abstract":"<jats:p>Resumo  Contexto A \u00falcera varicosa (UV) \u00e9 o est\u00e1gio mais avan\u00e7ado da doen\u00e7a venosa cr\u00f4nica (DVC) dos membros inferiores (MMII), frequentemente associada a epis\u00f3dios de hemorragia que podem provocar anemia cr\u00f4nica (AC) e retardar a sua cicatriza\u00e7\u00e3o. N\u00e3o h\u00e1, na literatura, trabalhos que avaliem a preval\u00eancia da AC nos portadores de UV dos MMII, e poucos trabalhos analisam o uso da pentoxifilina no tratamento das UV dos MMII.  Objetivos Avaliar a preval\u00eancia da AC nos pacientes portadores de UV de MMII e a resposta terap\u00eautica ao sulfato ferroso (SF) e a associa\u00e7\u00e3o da pentoxifilina com SF no tratamento adjuvante das UV dos MMII.  M\u00e9todos Foram avaliados 67 pacientes portadores de UV de MMII atendidos no ambulat\u00f3rio de Cirurgia Vascular do Hospital das Cl\u00ednicas, Recife, PE. Ap\u00f3s as avalia\u00e7\u00f5es cl\u00ednica e laboratorial iniciais, os pacientes diagnosticados com AC foram randomizados em dois grupos: o grupo controle, que recebeu SF (900 mg\/dia via oral), e o grupo de estudo, tratado com SF (900 mg\/dia via oral) e pentoxifilina (1.200 mg\/dia). Todos foram reavaliados ap\u00f3s 90 dias.  Resultados Entre os pacientes avaliados, 27 (40%) apresentavam AC. Ap\u00f3s o tratamento, foram observados aumento dos n\u00edveis de hemoglobina e de hemat\u00f3crito e melhora das taxas da cin\u00e9tica do ferro, assim como a diminui\u00e7\u00e3o da profundidade e da \u00e1rea das UV em ambos os grupos, sem diferen\u00e7a estat\u00edstica.  Conclus\u00f5es Foi encontrada alta preval\u00eancia de anemia na popula\u00e7\u00e3o estudada. A associa\u00e7\u00e3o do SF com a pentoxifilina n\u00e3o se mostrou mais eficaz do que o emprego isolado do SF no tratamento adjuvante da UV dos MMII.<\/jats:p>","DOI":"10.1590\/1677-5449.200167","type":"journal-article","created":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T20:18:49Z","timestamp":1621887529000},"source":"Crossref","is-referenced-by-count":1,"title":["Avalia\u00e7\u00e3o da pentoxifilina e do sulfato ferroso no tratamento da \u00falcera varicosa dos membros inferiores"],"prefix":"10.1590","volume":"20","author":[{"given":"Priscilla Cardoso","family":"Lemos","sequence":"first","affiliation":[{"name":"Universidade Federal de Pernambuco,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6603-6944","authenticated-orcid":false,"given":"Esdras Marques","family":"Lins","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pernambuco,  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