{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T22:51:36Z","timestamp":1772232696653,"version":"3.50.1"},"reference-count":38,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. vasc. bras."],"abstract":"<jats:p>Resumo  Contexto Os diab\u00e9ticos possuem risco de 5 a 15 vezes maior para o desenvolvimento de doen\u00e7a arterial perif\u00e9rica (DAP), e poucos estudos compararam fatores de risco e a distribui\u00e7\u00e3o e gravidade de altera\u00e7\u00f5es arteriais angiogr\u00e1ficas entre diab\u00e9ticos e n\u00e3o diab\u00e9ticos.  Objetivos Comparar altera\u00e7\u00f5es angiogr\u00e1ficas entre pacientes diab\u00e9ticos e n\u00e3o diab\u00e9ticos com DAP avan\u00e7ada, correlacionando-as com demais fatores de risco.  M\u00e9todos Trata-se de um estudo transversal retrospectivo de pacientes consecutivos submetidos a arteriografia de membros inferiores por DAP (Rutherford de 3 a 6), usando os escores angiogr\u00e1ficos TASC II e de Bollinger et al. Os crit\u00e9rios de exclus\u00e3o inclu\u00edram arteriografias de membros superiores, exames incompletos ou sem nitidez e cirurgias pr\u00e9vias. A an\u00e1lise estat\u00edstica incluiu o teste do qui-quadrado ou exato de Fisher para vari\u00e1veis discretas e o teste t para vari\u00e1veis cont\u00ednuas (signific\u00e2ncia: p &lt; 0,05).  Resultados Foram estudados 153 pacientes com idade m\u00e9dia de 67 anos, sendo 50,9% do sexo feminino e 58,2% diab\u00e9ticos. Um total de 91 pacientes (59%) tinha les\u00e3o tr\u00f3fica (Rutherford 5 ou 6), enquanto 62 (41%) tinham dor em repouso ou claudica\u00e7\u00e3o limitante (Rutherford 3 e 4). Entre os diab\u00e9ticos, 81,7% eram hipertensos, 29,4% nunca fumaram e 14% tinham antecedente de infarto do mioc\u00e1rdio. Pelo escore de Bollinger et al., as art\u00e9rias infrapopl\u00edteas foram as mais comprometidas, em especial a tibial anterior (p = 0,005) nos diab\u00e9ticos, enquanto a femoral superficial foi mais acometida nos n\u00e3o diab\u00e9ticos (p = 0,008). Pelo TASC II, as altera\u00e7\u00f5es arteriogr\u00e1ficas mais graves ocorreram no segmento f\u00eamoro-popl\u00edteo nos pacientes n\u00e3o diab\u00e9ticos (p = 0,019).  Conclus\u00f5es Os setores infrapopl\u00edteos foram os mais comprometidos nos diab\u00e9ticos, enquanto o setor femoral foi o mais acometido nos n\u00e3o diab\u00e9ticos.<\/jats:p>","DOI":"10.1590\/1677-5449.202000531","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T09:15:51Z","timestamp":1676020551000},"source":"Crossref","is-referenced-by-count":2,"title":["Compara\u00e7\u00e3o das altera\u00e7\u00f5es angiogr\u00e1ficas entre pacientes diab\u00e9ticos e n\u00e3o diab\u00e9ticos com doen\u00e7a arterial perif\u00e9rica"],"prefix":"10.1590","volume":"22","author":[{"given":"Giovanni Ortale","family":"Trainotti","sequence":"first","affiliation":[{"name":"Universidade Estadual Paulista,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8229-9848","authenticated-orcid":false,"given":"Jamil Victor","family":"Mari\u00faba","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6851-2841","authenticated-orcid":false,"given":"Matheus","family":"Bertanha","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2271-5878","authenticated-orcid":false,"given":"Marcone Lima","family":"Sobreira","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo de Alvarenga","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0455-9162","authenticated-orcid":false,"given":"Rodrigo Gibin","family":"Jaldin","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2622-286X","authenticated-orcid":false,"given":"Paula Angeleli Bueno de","family":"Camargo","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Winston Bonetti","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2023]]},"reference":[{"key":"ref1","series-title":"Doen\u00e7as vasculares perif\u00e9ricas","first-page":"1207","volume-title":"Patogenia e fisiopatologia da aterosclerose.","author":"Chacra APM","year":"2015","edition":"5."},{"key":"ref2","series-title":"Robbins Patologia B\u00e1sica","author":"Abbas AK","year":"2018"},{"issue":"3","key":"ref3","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1590\/S1677-54492005000300007","article-title":"Doen\u00e7a arterial obstrutiva perif\u00e9rica: que aten\u00e7\u00e3o temos dispensado \u00e0 abordagem cl\u00ednica dos pacientes?","volume":"4","author":"Durazzo AES","year":"2005","journal-title":"J Vasc Bras"},{"issue":"14","key":"ref4","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1056\/NEJMoa1406656","article-title":"Demographic and epidemiologic drivers of global cardiovascular mortality","volume":"372","author":"Roth GA","year":"2015","journal-title":"N Engl J Med"},{"issue":"2","key":"ref5","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1590\/S0066-782X2012005000061","article-title":"Mortalidade por doen\u00e7as cardiovasculares no Brasil e na regi\u00e3o metropolitana de S\u00e3o Paulo: atualiza\u00e7\u00e3o 2011","volume":"99","author":"Mansur AP","year":"2012","journal-title":"Arq Bras Cardiol"},{"issue":"1","key":"ref6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1590\/1677-5449.008916","article-title":"An\u00e1lise dos fatores de risco relacionados \u00e0s amputa\u00e7\u00f5es maiores e menores de membros inferiores em hospital terci\u00e1rio","volume":"16","author":"Jesus-Silva SG","year":"2017","journal-title":"J Vasc Bras"},{"issue":"2","key":"ref7","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1590\/S1677-54492008000200005","article-title":"Estudo comparativo da evolu\u00e7\u00e3o e sobrevida de pacientes com claudica\u00e7\u00e3o intermitente, com ou sem limita\u00e7\u00e3o para exerc\u00edcios, acompanhados em ambulat\u00f3rio espec\u00edfico","volume":"7","author":"Yoshida RA","year":"2008","journal-title":"J Vasc Bras"},{"issue":"24","key":"ref8","first-page":"39","article-title":"Peripheral arterial occlusive disease. 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