{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:09:22Z","timestamp":1755216562268,"version":"3.43.0"},"reference-count":12,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. vasc. bras."],"abstract":"<jats:p>Abstract  Background COVID-19 is a predominantly respiratory disease, but it also has a strong association with thromboembolism, especially among hospitalized patients.  Objectives To evaluate the prevalence of venous thromboembolism (VTE) and associated factors in patients with COVID-19 in a public hospital in the interior of South Brazil.  Methods A retrospective, cross-sectional observational study was carried out by analyzing data from medical records. The VTE outcome was a composite of acute pulmonary thromboembolism (PTE) and deep vein thrombosis (DVT). Associations were analyzed by logistic regression and bivariate analyses using Pearson\u2019s chi-square test.  Results The sample comprised 964 patients. 56% were male and 44% female, with a mean age of 58.2 \u00b1 15.1 years. 70% of patients were admitted to the ICU, 44.4% died, 97% required oxygen, and 63.7% required intubation. After adjusted analysis, the factors intubation (p=0.02) and prophylactic anticoagulation (p&lt;0.001) were associated with VTE. The following variables were shown to be important risk factors for VTE: intubation (OR 2.3; 95% CI 1.1-4.8, p=0.020) and excess weight (OR 3.3; 95% CI 0.2-2.2, p=0.02), while prophylactic anticoagulation showed a small protective factor (OR 0.02; 95% CI 0.01-0.04, p&lt;0.001).  Conclusions The results demonstrate how COVID-19, together with several other associated factors, especially intubation, excess weight, and use of anticoagulants, may be related to thromboembolism as risk factors and protective factors. Prophylactic anticoagulation, in particular, was a protective factor.<\/jats:p>","DOI":"10.1590\/1677-5449.202401432","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T14:43:54Z","timestamp":1754318634000},"source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of venous thromboembolism and associated factors in COVID-19 patients at a provincial public hospital in southern Brazil"],"prefix":"10.1590","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8302-6737","authenticated-orcid":false,"given":"Bruna Valduga","family":"Dutra","sequence":"first","affiliation":[{"name":"Universidade de Caxias do Sul,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8397-9247","authenticated-orcid":false,"given":"Luana Valduga","family":"Dutra","sequence":"additional","affiliation":[{"name":"Universidade de Caxias do Sul,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8099-0177","authenticated-orcid":false,"given":"Henrique Luiz","family":"Weber","sequence":"additional","affiliation":[{"name":"Universidade de Caxias do Sul,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7437-7423","authenticated-orcid":false,"given":"Matheus Omairi","family":"Reinheimer","sequence":"additional","affiliation":[{"name":"Universidade de Caxias do Sul,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5237-7382","authenticated-orcid":false,"given":"Matheos","family":"Pezzi","sequence":"additional","affiliation":[{"name":"Universidade de Caxias do Sul,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4302-8174","authenticated-orcid":false,"given":"Gabriela Teixeira","family":"Macalossi","sequence":"additional","affiliation":[{"name":"Universidade de Caxias do Sul,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7619-5930","authenticated-orcid":false,"given":"Simone","family":"Bonatto","sequence":"additional","affiliation":[{"name":"Universidade de Caxias do Sul,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6097-7249","authenticated-orcid":false,"given":"Clandio de Freitas","family":"Dutra","sequence":"additional","affiliation":[{"name":"Universidade de Caxias do Sul,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2025]]},"reference":[{"year":"2024","series-title":"WHO coronavirus disease (COVID-19) dashboard","key":"ref1"},{"issue":"5","key":"ref2","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/j.jvsv.2021.01.012","article-title":"A systematic review and meta-analysis of incidence, prognosis, and laboratory indicators of venous thromboembolism in hospitalized patients with coronavirus disease 2019","volume":"9","author":"Liu Y","year":"2021","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"issue":"10","key":"ref3","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1136\/thoraxjnl-2020-215383","article-title":"Arterial and venous thromboembolism in COVID-19: a study-level meta-analysis","volume":"76","author":"Tan BK","year":"2021","journal-title":"Thorax"},{"issue":"21","key":"ref4","doi-asserted-by":"crossref","first-page":"5373","DOI":"10.1182\/bloodadvances.2020003083","article-title":"Frequency of venous thromboembolism in 6513 patients with COVID-19: a retrospective study","volume":"4","author":"Hill JB","year":"2020","journal-title":"Blood Adv"},{"issue":"7","key":"ref5","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1055\/s-0040-1715456","article-title":"COVID-19 and venous thromboembolism: a meta-analysis of literature studies","volume":"46","author":"Di Minno A","year":"2020","journal-title":"Semin Thromb Hemost"},{"key":"ref6","doi-asserted-by":"crossref","DOI":"10.1590\/1677-5449.202300271","article-title":"Trombose venosa profunda de membros inferiores em pacientes com covid-19","volume":"22","author":"Saliba J\u00fanior OA","year":"2023","journal-title":"J Vasc Bras"},{"issue":"24","key":"ref7","doi-asserted-by":"crossref","first-page":"12944","DOI":"10.3390\/ijerph182412944","article-title":"Risk factors for venous thromboembolism in severe COVID-19: a study-level meta-analysis of 21 studies","volume":"18","author":"Lobbes H","year":"2021","journal-title":"Int J Environ Res Public Health"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","DOI":"10.2196\/22768","article-title":"Venous thromboembolism in hospitalized COVID-19 patients: systematic review","volume":"9","author":"Birkeland K","year":"2020","journal-title":"Interact J Med Res"},{"issue":"8","key":"ref9","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1111\/jth.14888","article-title":"Incidence of venous thromboembolism in hospitalized patients with COVID-19","volume":"18","author":"Middeldorp S","year":"2020","journal-title":"J Thromb Haemost"},{"issue":"6","key":"ref10","doi-asserted-by":"crossref","first-page":"e599","DOI":"10.1097\/MJT.0000000000001295","article-title":"Venous Thromboembolism in Hospitalized COVID-19 Patients","volume":"27","author":"Sridharan GK","year":"2020","journal-title":"Am J Ther"},{"issue":"4","key":"ref11","article-title":"Use of anticoagulants in patients with COVID-19: a living systematic review and meta-analysis","volume":"48","author":"Batista DR","year":"2022","journal-title":"J Bras Pneumol"},{"issue":"5","key":"ref12","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.orcp.2021.07.003","article-title":"Association of obesity with venous thromboembolism and myocardial injury in COVID-19","volume":"15","author":"Wang SY","year":"2021","journal-title":"Obes Res Clin Pract"}],"container-title":["Jornal Vascular Brasileiro"],"original-title":["Preval\u00eancia de tromboembolismo venoso e fatores associados em pacientes com COVID-19 em um hospital p\u00fablico do interior no Sul do Brasil"],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S1677-54492025000100317&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T14:43:58Z","timestamp":1754318638000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1677-54492025000100317&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":12,"alternative-id":["S1677-54492025000100317"],"URL":"https:\/\/doi.org\/10.1590\/1677-5449.202401432","relation":{"has-translation":[{"id-type":"doi","id":"10.1590\/1677-5449.202401431","asserted-by":"subject"}]},"ISSN":["1677-7301","1677-5449"],"issn-type":[{"type":"electronic","value":"1677-7301"},{"type":"print","value":"1677-5449"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"e20240143"}}