{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T11:06:39Z","timestamp":1790593599541,"version":"4.1.0"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. vasc. bras."],"abstract":"<jats:p>Abstract Post-sclerotherapy hyperpigmentation (PSH) is a common complication following sclerotherapy for telangiectasias and reticular veins. However, tools for pre-procedural prediction of PSH are limited, making pre-treatment identification of patients at greater risk a challenge. This research aimed to evaluate a clinical scoring system (Skin Code Score) designed to estimate the individual risk of PSH. A prospective, single-center, single-arm study was conducted. Adult female patients with telangiectasias and reticular veins were treated and evaluated for pigmentation risk using the Skin Code Score (range, 2-12 points). Hyperpigmentation was assessed at baseline and on day 30 by in-person evaluation performed by one vascular surgeon, complemented by photographic analysis conducted independently by two other vascular surgeons and one dermatologist. Skin Hyperpigmentation Index (SHI) measurements were used for objective correlation with the Skin Code Score. The Skin Code Score showed strong interobserver agreement and reproducibility (\u03ba \u2265 0.85). Diagnostic accuracy ranged from 82.8% to 94.7% among evaluators. A score of 12 predicted PSH in up to 99.8% of cases, while a score of 8 indicated a probability of approximately 76%. The study was limited by a small sample size and its single-center design; a proportion of the assessments were conducted by photographic analysis. It is concluded that the Skin Code Score is a simple and reproducible tool for predicting PSH and could assist clinicians with pre-procedural risk stratification, patient counseling, and clinical decision-making.<\/jats:p>","DOI":"10.1590\/1677-5449.202501082","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T10:52:28Z","timestamp":1790592748000},"source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of a clinical score to predict post-sclerotherapy hyperpigmentation compared with the Skin Hyperpigmentation Index: a prospective Skin Code study"],"prefix":"10.1590","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4054-6476","authenticated-orcid":false,"given":"Renata Camila Barros","family":"Rodrigues","sequence":"first","affiliation":[{"name":"Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de Misericordia de S\u00e3o Paulo","place":["S\u00e3o Paulo, SP, Brasil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2147-9092","authenticated-orcid":false,"given":"Samantha","family":"Neves","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de Misericordia de S\u00e3o Paulo","place":["S\u00e3o Paulo, SP, Brasil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5735-1333","authenticated-orcid":false,"given":"Eduardo","family":"Ramacciotti","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de Misericordia de S\u00e3o Paulo","place":["S\u00e3o Paulo, SP, Brasil"]},{"name":"Science Valley Research Institute","place":["S\u00e3o Paulo, SP, Brasil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviane Santana da","family":"Silva","sequence":"additional","affiliation":[{"name":"Science Valley Research Institute","place":["S\u00e3o Paulo, SP, Brasil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6352-4408","authenticated-orcid":false,"given":"Roberto Augusto","family":"Caffaro","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de Misericordia de S\u00e3o Paulo","place":["S\u00e3o Paulo, SP, Brasil"]},{"name":"Hospital Alem\u00e3o Oswaldo Cruz","place":["S\u00e3o Paulo, SP, Brasil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8272-812X","authenticated-orcid":false,"given":"Fl\u00e1via Magalh\u00e3es Silveira Magella","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Instituto de Infectologia Em\u00edlio Ribas","place":["S\u00e3o Paulo, SP, Brasil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8131-8958","authenticated-orcid":false,"given":"Alexandre","family":"Fioranelli","sequence":"additional","affiliation":[{"name":"Ambulat\u00f3rio M\u00e9dico de Especialidades Dr. Geraldo Paulo Bourroul","place":["S\u00e3o Paulo, SP, Brasil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0551-1410","authenticated-orcid":false,"given":"Rebeca Higino","family":"Becker","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de Misericordia de S\u00e3o Paulo","place":["S\u00e3o Paulo, SP, Brasil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2026]]},"reference":[{"issue":"7","key":"ref1","first-page":"20","article-title":"Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin 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