{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T11:57:34Z","timestamp":1774267054147,"version":"3.50.1"},"reference-count":10,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. vasc. bras."],"abstract":"<jats:p>Abstract Castleman\u2019s disease is a rare lymphoproliferative disorder that may present as unicentric or multicentric, with differing therapeutic implications. We report the case of a 23-year-old woman with unicentric Castleman\u2019s disease in the mediastinum. Following unsuccessful systemic therapy with corticosteroids and monoclonal antibodies, she underwent successful preoperative embolization using Embosphere\u00ae microspheres and subsequent robotic-assisted resection. This approach minimized blood loss (&lt;100 mL) and facilitated safe dissection in a surgically challenging region. The patient had an uneventful postoperative course and was discharged on postoperative day seven. This case highlights the benefits of combining embolization with robotic surgery in managing hypervascular mediastinal lesions, offering a minimally invasive and safe alternative in selected patients.<\/jats:p>","DOI":"10.1590\/1677-5449.202501672","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T11:05:10Z","timestamp":1774263910000},"source":"Crossref","is-referenced-by-count":0,"title":["Preoperative embolization and lung-sparing robotic surgery in intrathoracic Castleman\u2019s disease: case report"],"prefix":"10.1590","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0807-9552","authenticated-orcid":false,"given":"Felipe Furtado","family":"Leite","sequence":"first","affiliation":[{"name":"Universidade Federal da Bahia,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7972-0355","authenticated-orcid":false,"given":"Ricardo Sales dos","family":"Santos","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3063-9174","authenticated-orcid":false,"given":"Priscila Mina","family":"Falsarella","sequence":"additional","affiliation":[{"name":"Instituto Israelita de Ensino e Pesquisa Albert Einstein,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7157-8479","authenticated-orcid":false,"given":"Kau\u00ea Polizel","family":"Souza","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2940-9016","authenticated-orcid":false,"given":"Breno Boueri","family":"Affonso","sequence":"additional","affiliation":[{"name":"Instituto Israelita de Ensino e Pesquisa Albert Einstein,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6255-340X","authenticated-orcid":false,"given":"Leonardo Guedes Moreira","family":"Valle","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina do ABC,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4264-1482","authenticated-orcid":false,"given":"Mario Cl\u00e1udio","family":"Ghefter","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina do ABC,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6682-2259","authenticated-orcid":false,"given":"Felipe","family":"Nasser","sequence":"additional","affiliation":[{"name":"Universidade de Sao Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2026]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1056\/NEJM195401072500107","article-title":"CASE records of the Massachusetts General Hospital Weekly Clinicopathological Exercises: case 40011","volume":"250","author":"Cabot RC","year":"1954","journal-title":"N Engl J Med"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/s41572-021-00317-7","article-title":"Castleman disease","volume":"7","author":"Carbone A","year":"2021","journal-title":"Nat Rev Dis Primers"},{"issue":"16","key":"ref3","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1182\/blood.2019000931","article-title":"Overview of Castleman disease","volume":"135","author":"Dispenzieri A","year":"2020","journal-title":"Blood"},{"key":"ref4","article-title":"A national, multicenter, retrospective study of Castleman disease in China implementing CDCN criteria","volume":"34","author":"Zhang L","year":"2023","journal-title":"Lancet Reg Health West Pac"},{"issue":"9","key":"ref5","doi-asserted-by":"crossref","first-page":"E21","DOI":"10.1016\/S0022-3468(03)00421-4","article-title":"Preoperative embolization as an adjunct to the operative management of mediastinal Castleman disease","volume":"38","author":"Safford SD","year":"2003","journal-title":"J Pediatr Surg"},{"issue":"3","key":"ref6","doi-asserted-by":"crossref","first-page":"447","DOI":"10.2214\/ajr.130.3.447","article-title":"Giant mediastinal lymph node hyperplasia (Castleman\u2019s disease): angiographic and clinical features","volume":"130","author":"Walter JF","year":"1978","journal-title":"AJR Am J Roentgenol"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1007\/s00270-006-0156-y","article-title":"Terraz. 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